Einfluss der physikalischen Halbwertszeit auf die PET/CT-Bildgebung mit PSMA-spezifischen Radioliganden: Eine Simulationsstudie. (German)

Autor: Begum, NJ, Glatting, G, Eiber, M, Beer, AJ, Kletting, P

Publikováno v: NuclearMedicine / Nuklearmedizin; 2020, Vol. 59 Issue 2, p98-98, 1p

A mathematical model to improve Tumour Anti-Vascular Alpha Therapy (TAVAT) with 212 Pb-labelled monoclonal antibodies

Autor: Zaid, N, Begum, NJ, Kletting, P, Beer, AJ, Glatting, G

Publikováno v: Nuklearmedizin. Nuclear medicine; April 2020, Vol. 59 Issue: 2

Important pharmacokinetic parameters for individualization of ¹⁷⁷ Lu-PSMA therapy: A global sensitivity analysis for a physiologically-based pharmacokinetic model.

Autor: Hardiansyah D; Medical Physics and Biophysics, Physics Department, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, 16424, Indonesia., Kletting P; Medical Radiation Physics, Department of Nuclear Medicine, Ulm University, Ulm, 89081, Germany.; Department of Nuclear Medicine, Ulm University, Ulm, 89081, Germany., Begum NJ; Medical Radiation Physics, Department of Nuclear Medicine, Ulm University, Ulm, 89081, Germany., Eiber M; Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universität München, München, 81675, Germany., Beer AJ; Department of Nuclear Medicine, Ulm University, Ulm, 89081, Germany., Pawiro SA; Medical Physics and Biophysics, Physics Department, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, 16424, Indonesia., Glatting G; Medical Radiation Physics, Department of Nuclear Medicine, Ulm University, Ulm, 89081, Germany.; Department of Nuclear Medicine, Ulm University, Ulm, 89081, Germany.

Publikováno v: Medical physics [Med Phys] 2021 Feb; Vol. 48 (2), pp. 556-568. Date of Electronic Publication: 2020 Dec 15.

The effect of ligand amount, affinity and internalization on PSMA-targeted imaging and therapy: A simulation study using a PBPK model.

Autor: Begum NJ; Medical Radiation Physics, Department of Nuclear Medicine, Ulm University, Ulm, Germany. nusrat.begum@uni-ulm.de., Glatting G; Medical Radiation Physics, Department of Nuclear Medicine, Ulm University, Ulm, Germany.; Department of Nuclear Medicine, Ulm University, Ulm, Germany., Wester HJ; Technical University of Munich, Pharmaceutical Radiochemistry, Munich, Germany., Eiber M; Technical University of Munich, School of Medicine, Klinikum rechts der Isar, Department of Nuclear Medicine, Munich, Germany., Beer AJ; Department of Nuclear Medicine, Ulm University, Ulm, Germany., Kletting P; Medical Radiation Physics, Department of Nuclear Medicine, Ulm University, Ulm, Germany.; Department of Nuclear Medicine, Ulm University, Ulm, Germany.

Publikováno v: Scientific reports [Sci Rep] 2019 Dec 27; Vol. 9 (1), pp. 20041. Date of Electronic Publication: 2019 Dec 27.

Sensitivity Analysis of a Physiologically Based Pharmacokinetic Model Used for Treatment Planning in Peptide Receptor Radionuclide Therapy.

Autor: Hardiansyah D; 1 Medical Radiation Physics/Radiation Protection, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University , Mannheim, Germany .; 2 Department of Radiation Oncology, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University , Mannheim, Germany ., Begum NJ; 1 Medical Radiation Physics/Radiation Protection, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University , Mannheim, Germany .; 3 Digitale Signalverarbeitung , Information Technology Faculty, Hochschule Mannheim, Mannheim, Germany ., Kletting P; 4 Department of Nuclear Medicine, University Hospital Ulm , Ulm, Germany ., Mottaghy FM; 5 Klinik für Nuklearmedizin, University Hospital, RWTH Aachen University , Aachen, Germany .; 6 Department of Nuclear Medicine, Maastricht University Medical Center (MUMC+) , Maastricht, The Netherlands ., Glatting G; 1 Medical Radiation Physics/Radiation Protection, Universitätsmedizin Mannheim, Medical Faculty Mannheim, Heidelberg University , Mannheim, Germany .

Publikováno v: Cancer biotherapy & radiopharmaceuticals [Cancer Biother Radiopharm] 2016 Aug; Vol. 31 (6), pp. 217-24. Date of Electronic Publication: 2016 Jul 12.