Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Begum Gokcen Akkaya"'
Autor:
Aleksandra Adamska, Alice Domenichini, Emily Capone, Verena Damiani, Begum Gokcen Akkaya, Kenneth J. Linton, Pierluigi Di Sebastiano, Xi Chen, Adam B. Keeton, Veronica Ramirez-Alcantara, Yulia Maxuitenko, Gary A. Piazza, Vincenzo De Laurenzi, Gianluca Sala, Marco Falasca
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Abstract Background Pancreatic Ductal Adenocarcinoma (PDAC) is an aggressive and lethal disease, lacking effective therapeutic approaches. Available therapies only marginally prolong patient survival and are frequently coupled with severe adverse eve
Externí odkaz:
https://doaj.org/article/84712f0b99aa425c917bb4104624a84d
Autor:
Kenneth J. Linton, Gary A. Piazza, Alice Domenichini, Aleksandra Adamska, Xi Chen, Verena Damiani, Emily Capone, Begum Gokcen Akkaya, Pierluigi Di Sebastiano, Adam B. Keeton, Gianluca Sala, Veronica Ramirez-Alcantara, Marco Falasca, Yulia Maxuitenko, Vincenzo De Laurenzi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-14 (2019)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Pancreatic Ductal Adenocarcinoma (PDAC) is an aggressive and lethal disease, lacking effective therapeutic approaches. Available therapies only marginally prolong patient survival and are frequently coupled with severe adverse events. It i
Autor:
Federica Guffanti, Ilaria Casari, Xi Chen, Massimo Broggini, Tania Maffucci, Kenneth J. Linton, Gary A. Piazza, Luc Furic, Begum Gokcen Akkaya, Aikaterini Emmanouilidi, Adam B. Keeton, Marco Falasca, Yulia Maxuitenko
Publikováno v:
Cancers
Volume 12
Issue 8
Cancers, Vol 12, Iss 2022, p 2022 (2020)
Volume 12
Issue 8
Cancers, Vol 12, Iss 2022, p 2022 (2020)
Expression of ATP-binding cassette (ABC) transporters has long been implicated in cancer chemotherapy resistance. Increased expression of the ABCC subfamily transporters has been reported in prostate cancer, especially in androgen-resistant cases. AB
Autor:
Aleksandra Adamska, Rossano Lattanzio, Marco Falasca, Verena Damiani, Kenneth J. Linton, Emily Capone, Vincenzo De Laurenzi, Alice Domenichini, Gianluca Sala, Riccardo Ferro, Giovanna Chiorino, Begum Gokcen Akkaya
Publikováno v:
Advances in biological regulation. 73
Pancreatic Ductal Adenocarcinoma (PDAC) is a very aggressive disease, lacking effective therapeutic approaches and leaving PDAC patients with a poor prognosis. The life expectancy of PDAC patients has not experienced a significant change in the last
Autor:
Anika M.S. Hartz, Begum Gokcen Akkaya, James A. Sullivan, Kenneth J. Linton, Tasha K. Ritchie, Joseph K. Zolnerciks, Bjoern Bauer
Publikováno v:
Molecular membrane biology. 32(2)
The ATP Binding Cassette transporter ABCB1 can export the neurotoxic peptide β-amyloid from endothelial cells that line the blood-brain barrier (BBB). This has the potential to lower cerebral levels of β-amyloid, but ABCB1 expression in the BBB app
Autor:
Kenneth J. Linton, Marjolein Snippe, Peter Chiba, Joseph K. Zolnerciks, Begum Gokcen Akkaya, Anna Seelig
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28(10)
For a primary active pump, such as the human ATP-binding-cassette (ABC) transporter ABCB1, coupling of drug-binding by the two transmembrane domains (TMDs) to the ATP catalytic cycle of the two nucleotide-binding domains (NBDs) is fundamental to the