Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Begona Porteiro"'
Autor:
Domenico Sergi, Fiona M. Campbell, Christine Grant, Amanda C. Morris, Eva-Maria Bachmair, Christiane Koch, Fiona H. McLean, Aifric Muller, Nigel Hoggard, Baukje de Roos, Begona Porteiro, Mark V. Boekschoten, Fiona C. McGillicuddy, Darcy Kahn, Phyllis Nicol, Jonas Benzler, Claus-Dieter Mayer, Janice E. Drew, Helen M. Roche, Michael Muller, Ruben Nogueiras, Carlos Dieguez, Alexander Tups, Lynda M. Williams
Publikováno v:
Genes & Nutrition, Vol 13, Iss 1, Pp 1-14 (2018)
Abstract Background Energy homeostasis is regulated by the hypothalamus but fails when animals are fed a high-fat diet (HFD), and leptin insensitivity and obesity develops. To elucidate the possible mechanisms underlying these effects, a microarray-b
Externí odkaz:
https://doaj.org/article/f5bb12ec5e87442284aa5620612107c2
Autor:
Devesh Mishra, Jennifer E. Richard, Ivana Maric, Begona Porteiro, Martin Häring, Sander Kooijman, Saliha Musovic, Kim Eerola, Lorena López-Ferreras, Eduard Peris, Katarzyna Grycel, Olesya T. Shevchouk, Peter Micallef, Charlotta S. Olofsson, Ingrid Wernstedt Asterholm, Harvey J. Grill, Ruben Nogueiras, Karolina P. Skibicka
Publikováno v:
Cell Reports, Vol 26, Iss 11, Pp 3011-3026.e5 (2019)
Summary: Chronic low-grade inflammation and increased serum levels of the cytokine IL-6 accompany obesity. For brain-produced IL-6, the mechanisms by which it controls energy balance and its role in obesity remain unclear. Here, we show that brain-pr
Externí odkaz:
https://doaj.org/article/b644b6194e34414bbe3b4e291313ba4c
Autor:
Begoña Porteiro, Reinout L.P. Roscam Abbing, Wietse In het Panhuis, Dirk R. de Waart, Suzanne Duijst, Isabelle Bolt, Esther W. Vogels, Johannes H.M. Levels, Laura A. Bosmans, Winnie G. Vos, Ronald P.J. Oude Elferink, Esther Lutgens, Stan F.J. van de Graaf
Publikováno v:
Journal of Lipid Research, Vol 65, Iss 8, Pp 100594- (2024)
Bile salts can strongly influence energy metabolism through systemic signaling, which can be enhanced by inhibiting the hepatic bile salt transporter Na+ taurocholate cotransporting polypeptide (NTCP), thereby delaying hepatic reuptake of bile salts
Externí odkaz:
https://doaj.org/article/3ec125e1e6b34037b16340136513ac67
Autor:
Marcos F. Fondevila, Eva Novoa, Uxia Fernandez, Valentina Dorta, Tamara Parracho, Henriette Kreimeyer, Maria Garcia-Vence, Maria P. Chantada-Vazquez, Susana B. Bravo, Begoña Porteiro, Alba Cabaleiro, Mijra Koning, Ana Senra, Yara Souto, Joanne Verheij, Diana Guallar, Miguel Fidalgo, Abraham S. Meijnikman, Natalia da Silva Lima, Carlos Dieguez, Maria J. Gonzalez-Rellan, Ruben Nogueiras
Publikováno v:
Molecular Metabolism, Vol 85, Iss , Pp 101962- (2024)
Objective: p63 is a transcription factor involved in multiple biological functions. In the liver, the TAp63 isoform induces lipid accumulation in hepatocytes. However, the role of liver TAp63 in the progression of metabolic dysfunction-associated ste
Externí odkaz:
https://doaj.org/article/59d4e4a6312e4306b7882162a12d2f0b
Autor:
Begona Porteiro Couto, Patricia Aspichueta, Rubén Nogueiras, Alfonso Mora, Xabier Buqué, Carlos Dieguez, Maria Jesus Gonzalez Rellan, Miguel López, Marcos F. Fondevila, Guadalupe Sabioc, Daniel Beiroa, Uxia Fernandez
Publikováno v:
Endocrine Abstracts.
Autor:
Pozo Ruben Nogueiras, Xabier Buqué, Patricia Aspichueta, Rosalia Gallego, Coto Begona Porteiro, Ana Senra, Alfonso Mora, Miguel Lopez, Fondevila Marcos Fernández, Paz Uxia Fernandez, Gonzalez Rellan Maria Jesus, Guadalupe Sabio, Carlos Dieguez, Daniel Beiroa
Publikováno v:
Endocrine Abstracts.
Autor:
Tomás García-Caballero, Helen C. Christian, David González-Touceda, Begona Porteiro Couto, Iain P. Hargreaves, John Parrington, Pamela V. Lear, Vanessa Guymer, Carlos Dieguez, Patricia Viaño, Elena Remzova, Patricia W. Tynan, Ruth Tunn, Rubén Nogueiras, Annapurna Chalasani
Publikováno v:
Endocrinology. 156(3)
Intracellular calcium-permeable channels have been implicated in thermogenic function of murine brown and brite/beige adipocytes, respectively transient receptor potential melastin-8 and transient receptor potential vanilloid-4. Because the endo-lyso
Autor:
Diego Sáenz de Urturi, Xabier Buqué, Begoña Porteiro, Cintia Folgueira, Alfonso Mora, Teresa C. Delgado, Endika Prieto-Fernández, Paula Olaizola, Beatriz Gómez-Santos, Maider Apodaka-Biguri, Francisco González-Romero, Ane Nieva-Zuluaga, Mikel Ruiz de Gauna, Naroa Goikoetxea-Usandizaga, Juan Luis García-Rodríguez, Virginia Gutierrez de Juan, Igor Aurrekoetxea, Valle Montalvo-Romeral, Eva M. Novoa, Idoia Martín-Guerrero, Marta Varela-Rey, Sanjay Bhanot, Richard Lee, Jesus M. Banales, Wing-Kin Syn, Guadalupe Sabio, María L. Martínez-Chantar, Rubén Nogueiras, Patricia Aspichueta
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
High methionine and S-adenosylmethionine serum levels are related with obesity. Here the authors show that knockdown of methionine adenosyltransferase by using antisense oligonucleotides provides beneficial effects in obesity and comorbidities.
Externí odkaz:
https://doaj.org/article/679efae112224ba6a2829203d49df6dc
Autor:
Maria J. Gonzalez-Rellan, Marcos F. Fondevila, Uxia Fernandez, Amaia Rodríguez, Marta Varela-Rey, Christelle Veyrat-Durebex, Samuel Seoane, Ganeko Bernardo, Fernando Lopitz-Otsoa, David Fernández-Ramos, Jon Bilbao, Cristina Iglesias, Eva Novoa, Cristina Ameneiro, Ana Senra, Daniel Beiroa, Juan Cuñarro, Maria DP Chantada-Vazquez, Maria Garcia-Vence, Susana B. Bravo, Natalia Da Silva Lima, Begoña Porteiro, Carmen Carneiro, Anxo Vidal, Sulay Tovar, Timo D. Müller, Johan Ferno, Diana Guallar, Miguel Fidalgo, Guadalupe Sabio, Stephan Herzig, Won Ho Yang, Jin Won Cho, Maria Luz Martinez-Chantar, Roman Perez-Fernandez, Miguel López, Carlos Dieguez, Jose M. Mato, Oscar Millet, Roberto Coppari, Ashwin Woodhoo, Gema Fruhbeck, Ruben Nogueiras
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-21 (2021)
p53 regulates signalling pathways involved in metabolic homeostasis. Here the authors show that O-GlcNAcylation of p53 in the liver plays a key role in the physiological regulation of glucose homeostasis, potentially via controlling the expression of
Externí odkaz:
https://doaj.org/article/9769f87dfa1c4d5b90bfa5688f97fb4c
Autor:
Miguel Lopez, Begona Porteiro Couto, Daniel Beiroa Tarrio, Rubén Nogueiras, David Gonzalez Touceda, Amparo Romero Pico, Monica Imbernon Piedra, Carlos Dieguez
Publikováno v:
Endocrine Abstracts.