Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Begona Barroso"'
Autor:
Jan van Dijk, Dorien Groenendaal-van de Meent, Martin den Adel, Georg Golor, Marloes Schaddelee, Begona Barroso-Fernandez, Virginie Kerbusch
Publikováno v:
Clinical Therapeutics. 43:1079-1091
Purpose Roxadustat, a hypoxia-inducible factor prolyl hydroxylase inhibitor, treats anemia in chronic kidney disease. Hyperphosphatemia, a common complication in chronic kidney disease, is treated with phosphate binders (PBs). This study in healthy i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56a76a6caf52aa0ace080d0f5d3be187
https://doi.org/10.1016/j.clinthera.2021.03.025
https://doi.org/10.1016/j.clinthera.2021.03.025
Autor:
Rudiger Kaspera, Gernot K Klein, Begona Barroso-Fernandez, Virginie Kerbusch, Dorien Groenendaal-van de Meent, Martin den Adel, Piergiorgio Galletti
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics
Background and Objectives Roxadustat is an orally active hypoxia-inducible factor prolyl hydroxylase inhibitor for anemia in chronic kidney disease. The pharmacokinetics, metabolic profile, and pharmacodynamics of roxadustat were investigated in subj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aea43944ad37bbef9946e003f2f88672
http://europepmc.org/articles/PMC7811989
http://europepmc.org/articles/PMC7811989
Autor:
Rudiger Kaspera, Martin den Adel, Gernot K Klein, Virginie Kerbusch, Begona Barroso-Fernandez, Piergiorgio Galletti, Dorien Groenendaal-van de Meent
Publikováno v:
Nephrology Dialysis Transplantation. 35
Background and Aims Roxadustat is an orally active hypoxia-inducible factor prolyl hydroxylase inhibitor used at titrated doses to treat anaemia in CKD patients. This study investigated the pharmacokinetics (PK), metabolic profile, pharmacodynamics,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c07db61cb29bde5448aa021d5cd1abde
https://doi.org/10.1093/ndt/gfaa139.so052
https://doi.org/10.1093/ndt/gfaa139.so052
Autor:
Dorien Groenendaal-van de Meent, Jan van Dijk, Rachid El Galta, Georg Golor, Marloes Schaddelee, Begona Barroso-Fernandez, Martin den Adel
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics
Background and Objectives Roxadustat is an orally active hypoxia-inducible factor prolyl hydroxylase inhibitor for the treatment of anemia in chronic kidney disease. This study investigated the effect of multiple daily oral doses of omeprazole on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92bc44e831e47b915c1b8f73a934e883
http://europepmc.org/articles/PMC6244714
http://europepmc.org/articles/PMC6244714
Autor:
John Allinson, Sidath Katugampola, Philip Timmerman, Marianne Scheel Fjording, Ulrich Kunz, Elizabeth S. Hickford, Ulf Diczfalusy, Adrian Freeman, Robert Nelson, Hamza Kandousi, Begona Barroso, Cecilia Arfvidsson, John Smeraglia
Publikováno v:
Bioanalysis. 9:675-681
European Bioanalysis Forum Focus Workshop, Lisbon, Portugal, 9–10 June 2016 At the recent European Bioanalysis Forum's Focus Workshop ‘Bringing Assay Validation and Analysis of Biomarkers into Practice’, the discussion on best practice for biom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc0f1656817f7672b1fbda2ceeb810f4
https://doi.org/10.4155/bio-2017-0045
https://doi.org/10.4155/bio-2017-0045
Publikováno v:
Analytical biochemistry. 559
The aim of this work was to assess the influence of preanalytical variables on the stability of two endogenous opioid peptides (Methionine-Enkephalin and Leucine-Enkephalin) in human plasma. For this purpose, first a sensitive LC-MS/MS analytical met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcc3cc8a88ad9af578f1727c50daff18
https://pubmed.ncbi.nlm.nih.gov/29981318
https://pubmed.ncbi.nlm.nih.gov/29981318
Autor:
Begona Barroso, Christian Herling, Stephanie Fischmann, Neil Henderson, Philip Timmerman, Karen Elsby, Clare Kingsley, Susanne Pihl, Birgit Jaitner, Ulrich Kunz, Amanda Versteilen, Stewart Bates, Daniela Stoellner, Arjen Companjen
Publikováno v:
Bioanalysis. 4:1883-1894
Biomarkers have become increasingly important in drug development and many bioanalysts are getting involved. Consequently, different views on how to approach the bioanalysis of biomarkers have been published or are being developed. The European Bioan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5ca1fa6281b41dc4beae5de7ddff0ca
https://doi.org/10.4155/bio.12.164
https://doi.org/10.4155/bio.12.164
Autor:
Michaela Golob, Peter van Amsterdam, Birgitte Buur Rasmussen, Daniela Stoellner, Ben Gordon, Eva Vieser, Richard Abbott, Dijksman Jessica A R, Arjen Companjen, Philip Timmerman, Christian Herling, Begona Barroso, Margarete Brudny Kloeppel, Graeme Young, Silke Luedtke, Magnus Knutsson
Publikováno v:
Bioanalysis. 4:633-642
The 4th Open Symposium of the European Bioanalytical Forum entitled ‘Less is More’ was held on 16–18 November 2011 at the Hesperia Tower Hotel, Barcelona, Spain. More than 50 interesting presentations were delivered covering areas with interest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc7c02d276bf47a43d7f12659a84a997
https://doi.org/10.4155/bio.12.36
https://doi.org/10.4155/bio.12.36
Publikováno v:
Talanta, 80(4), 1503-1512. ELSEVIER SCIENCE BV
Protein tyrosine nitration (PTN) is a post-translational modification of proteins associated with a number of inflammatory diseases. While PTN is rather selective (not all proteins are modified and within a protein, only certain tyrosines are subject
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeeb440d5851c55da81b8b78f8afb4af
https://research.rug.nl/en/publications/5f5eaca2-c82a-4dba-9f41-90a7a9765020
https://research.rug.nl/en/publications/5f5eaca2-c82a-4dba-9f41-90a7a9765020
Autor:
Machteld N. Hylkema, Nick H. T. ten Hacken, Begona Barroso, Dirkje S. Postma, Wim Timens, Bea Rutgers, Brigitte W. M. Willemse, Marie Geerlings, Mieke Versluis
Publikováno v:
Virchows Archiv, 454(3), 273-281. SPRINGER
Our group has shown that 1-year smoking cessation persisted or increased airway inflammation in chronic obstructive pulmonary disease (COPD). We compared adenosine and adenosine receptor (AR) expression in COPD and asymptomatic smokers (AS) before an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2164b54a1368867d0715df300a401e28
https://doi.org/10.1007/s00428-009-0727-9
https://doi.org/10.1007/s00428-009-0727-9