Blood gene expression biomarkers of response to anti-TNF drugs in pediatric inflammatory bowel diseases before initiation of treatment

Autor: Sara Salvador-Martín, Gianluca Rubbini, Perceval Vellosillo, Paula Zapata-Cobo, Marta Velasco, Laura M. Palomino, Susana Clemente, Oscar Segarra, Ana Moreno-Álvarez, Ana Fernández-Lorenzo, Begoña Pérez-Moneo, Montserrat Montraveta, Cesar Sánchez, Mar Tolín, Inés Loverdos, María José Fobelo, Victor Manuel Navas-López, Lorena Magallares, Ruth García-Romero, Ricardo Torres-Peral, Alejandro Rodríguez, Ferrán Bossacoma, Vicente Merino-Bohórquez, Enrique Salcedo, Rebeca Álvarez, Ana Dopazo, María Sanjurjo-Sáez, Luis A. López-Fernández

Publikováno v: Biomedicine & Pharmacotherapy, Vol 173, Iss , Pp 116299- (2024)

Background/aims: Changes in gene expression profiles among individuals with inflammatory bowel diseases (IBDs) could potentially influence the responsiveness to anti-TNF treatment. The aim of this study was to identify genes that could serve as predi

Externí odkaz: https://doaj.org/article/4b0faa08ee99409eb3ae49564d84206d

Polymorphisms indicating risk of inflammatory bowel disease or antigenicity to anti-TNF drugs as biomarkers of response in children

Autor: Paula Zapata-Cobo, Sara Salvador-Martín, Marta Velasco, Laura M. Palomino, Susana Clemente, Oscar Segarra, Ana Moreno-Álvarez, Ana Fernández-Lorenzo, Begoña Pérez-Moneo, Montserrat Montraveta, Cesar Sánchez, Mar Tolín, Inés Loverdos, María Jesús Fobelo, Victor Manuel Navas-López, Lorena Magallares, Ruth García-Romero, José Germán Sánchez-Hernández, Alejandro Rodríguez, Ferrán Bossacoma, María Jesús Balboa, Enrique Salcedo, María Sanjurjo-Sáez, Luis A. López-Fernández

Publikováno v: Pharmacological Research, Vol 194, Iss , Pp 106859- (2023)

Few genetic polymorphisms predict early response to anti-TNF drugs in inflammatory bowel disease (IBD), and even fewer have been identified in the pediatric population. However, it would be of considerable clinical interest to identify and validate g

Externí odkaz: https://doaj.org/article/932b1c7582b3485494608f6bff4859d4

COVID-19: Critical appraisal of the evidence

Autor: Paz González Rodríguez, Begoña Pérez-Moneo Agapito, María Salomé Albi Rodríguez, Pilar Aizpurua Galdeano, María Aparicio Rodrigo, María Mercedes Fernández Rodríguez, María Jesús Esparza Olcina, Carlos Ochoa Sangrador

Publikováno v: Anales de Pediatría (English Edition), Vol 95, Iss 3, Pp 207.e1-207.e13 (2021)

We present the summary of a critical appraisal document of the available evidence on COVID-19, developed with a clinical practice guide format following GRADE methodology. The document tries to provide answers to a series of structured clinical quest

Externí odkaz: https://doaj.org/article/62c1c08c9c534becaec0213257f39cd0

'Geographical distribution of risk genotypes in pediatric patients with celiac disease in Spain'

Autor: Félix Sánchez-Valverde, Eva Martínez-Ojinaga, Ester Donat, Andrés Bodas, Eva Bandrés, Ricardo Torres, Berta Ibáñez, Mª Luz Cilleruelo, Gemma Castillejo, David Pérez-Solis, Carlos Ochoa, Francisco Javier Eizaguirre, Salvador García, Jose Ignacio García, Josefa Barrio, Raquel Vecino, María del Carmen Miranda, Mercedes Juste, Jose Carlos Salazar, Honorio Armas, Luis Ortigosa, Pedro Urruzuno, Zuriñe García, Elena Balmaseda, Cecilia Martinez-Costa, Enrique La Orden, Pilar Codoñer, Amadeu Roca, Carlos Trillo, Mercedes Sebastian, Ruth García, Luis Peña-Quintana, Patricia Barros, Marta Soria, Roger García, Begoña Pérez-Moneo, Isabel Polanco, Carmen Ribes, Enriqueta Román, Margarita Pich, Ana Arévalo, Sonia Fernández, David Gil, Pablo Oliver, Juan Manuel Bartolomé, José Vicente Arcos, Francisco Pérez, Haydeé Expósito, Juana M. Rizo, Víctor Manuel Navas, Rafael González de Caldas, María Jesús Balboa, Cristina Molinos, Laura Alonso, Helena Lorenzo, José Bernardo González, María Lluïsa Masiques, Ana Isabel Ruiz, José Ignacio Olazábal

Publikováno v: Human Immunology. 84:290-295

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::780c049d931661a3a7aa6308d80d19b8
https://doi.org/10.1016/j.humimm.2023.01.010

Changes in Ventilation Practices for Bronchiolitis in the Hospital Ward and Need for ICU Transfer over the Last Decade

Autor: Ruth Solana-Gracia, Vicent Modesto i Alapont, Leticia Bueso-Inchausti, María Luna-Arana, Ariadna Möller-Díez, Alberto Medina, Begoña Pérez-Moneo

Publikováno v: Journal of Clinical Medicine; Volume 11; Issue 6; Pages: 1622
E-Prints Complutense. Archivo Institucional de la UCM
Universidad Europea (UEM)

There is limited evidence of the potential benefits of the use of high-flow nasal cannula (HFNC) for the management of bronchiolitis in the ward. Our aim is to describe the ventilation trends for bronchiolitis in our hospital along with the introduct

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d619af02221ba3cf3f26aa6fdb1dda