Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Begoña Jiménez-Rodríguez"'
Autor:
Alfonso Alba-Bernal, Ana Godoy-Ortiz, María Emilia Domínguez-Recio, Esperanza López-López, María Elena Quirós-Ortega, Victoria Sánchez-Martín, María Dunia Roldán-Díaz, Begoña Jiménez-Rodríguez, Jesús Peralta-Linero, Estefanía Bellagarza-García, Laura Troyano-Ramos, Guadalupe Garrido-Ruiz, M. Isabel Hierro-Martín, Luis Vicioso, Álvaro González-Ortiz, Noelia Linares-Valencia, Jesús Velasco-Suelto, Guillermo Carbajosa, Alicia Garrido-Aranda, Rocío Lavado-Valenzuela, Martina Álvarez, Javier Pascual, Iñaki Comino-Méndez, Emilio Alba
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Early breast cancer patients often experience relapse due to residual disease after treatment. Liquid biopsy is a methodology capable of detecting tumor components in blood, but low concentrations at early stages pose challenges. To detect t
Externí odkaz:
https://doaj.org/article/bd142254ea644db1a1eebb2a629ad70a
Autor:
Begoña Jiménez-Rodríguez, Alfonso Alba-Bernal, Esperanza López-López, María Elena Quirós-Ortega, Guillermo Carbajosa, Alicia Garrido-Aranda, Martina Álvarez, Ana Godoy-Ortiz, María Isabel Queipo-Ortuño, Luis Vicioso, Gema Díaz-Córdoba, María Dunia Roldán-Díaz, Jesús Velasco-Suelto, Cristina Hernando, Begoña Bermejo, Ana Julve-Parreño, Ana Lluch, Javier Pascual, Iñaki Comino-Méndez, Emilio Alba
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 146 (2022)
Breast cancer (BC) is the most prevalent cancer in women. While usually detected when localized, invasive procedures are still required for diagnosis. Herein, we developed a novel ultrasensitive pipeline to detect circulating tumor DNA (ctDNA) in a s
Externí odkaz:
https://doaj.org/article/2f67b0e0538a475fb2b1d161a6d6a0a9
Autor:
Joaquín Gavilá Gregori, Elena López Miranda, Santiago Escrivá-de-Romaní, Begoña Jiménez Rodríguez, Silvia Antolín Novoa, Luis Fernández Morales, Elena Galve Calvo, Lucía González Cortijo, Antonia Perelló Martorell, Julián Lagunar Ruiz, Santiago González Santiago
Publikováno v:
Cancer Research. 82:OT1-12
Type: Trial in progress. Introduction: Sequential intravenous (IV) treatment with pertuzumab and trastuzumab is effective in disrupting HER2 signalling in early and advanced HER2-positive breast cancer (BC). However, this strategy increases patient
Autor:
Martine Piccart, Audrey Hennequin, Manuel Ruiz Borrego, Santiago Escrivá-de-Romani, Anja Williams, Begoña Jiménez Rodríguez, Gianluca Del Conte, Sacha J. Howell, Michela Palleschi, Matteo Simonelli, Francois P. Duhoux, Diego Tosi, Bernard Doger de Speville Uribe, Yolanda Jerez Gilarranz, Pierfrancesco Tassone, Giuseppe Curigliano, Simon Waters, Philippe Aftimos, Hans Wildiers, Simona Scartoni, Bartomeu Piza Vallespir, Ram Charan Shankaraiah, Krzysztof Grzegorzewski, Nassir Habboubi
Publikováno v:
Cancer Research. 83:PD18-05
Background: MEN1611 (MEN) is an oral PI3K inhibitor active on the p110α mutant and wild type, β and γ isoforms, while sparing the δ. B-PRECISE-01 is an open-label, 2-arm, phase 1b study investigating MEN1611 in combination with trastuzumab ± ful
Autor:
Ángela Santonja, Aurelio A. Moya-García, Nuria Ribelles, Begoña Jiménez-Rodríguez, Bella Pajares, Cristina E. Fernández-De Sousa, Elísabeth Pérez-Ruiz, María del Monte-Millán, Manuel Ruiz-Borrego, Juan de la Haba, Pedro Sánchez-Rovira, Atocha Romero, Anna González-Neira, Ana Lluch, Emilio Alba
Publikováno v:
Oncotarget. 13
Most cancer-related deaths in breast cancer patients are associated with metastasis, a multistep, intricate process that requires the cooperation of tumour cells, tumour microenvironment and metastasis target tissues. It is accepted that metastasis d
Autor:
Wesley Buckingham, I. Rodrigo, Cesar E. Ramirez, Carl Schaper, Luis Vicioso, V. de Luque, Ester Villar, Emiliano Zamora de Alba, C González-Hermoso, Naeem Dowidar, M José Lozano, Nuria Ribelles, P. Sanchez Rovira, Begoña Jiménez-Rodríguez, R Chica Parrado, Ana Inés Fernández, Aleix Prat, M. Alvarez, Sean Ferree, Arthur Jeiranian, Irene Zarcos
Publikováno v:
Cancer Research. 76:P3-07
Background: Prosigna's ROR score was demonstrated as a strong predictor of response to NAC in a representative cohort of EBC patients including HR+/HER2- N0-N1 patients.1 Given that the ROR score is partially derived from the correlation of the tumor
Autor:
P. Sanchez Rovira, Ester Villar, V. de Luque, Antonio Núñez Jiménez, Irene Zarcos, C González-Hermoso, A Isabel Fernandez, Sean Ferree, Arthur Jeiranian, Begoña Jiménez-Rodríguez, Wesley Buckingham, Carl Schaper, Naeem Dowidar, Cesar E. Ramirez, Emiliano Zamora de Alba, Luis Vicioso, Angela Santonja, Nuria Ribelles, C. Fernandez de Sousa, Aleix Prat, M. Alvarez
Publikováno v:
Cancer Research. 76:P3-07
Background: The role of the HER2-enriched (HER2E) subtype determined by the Prosigna Assay in the neoadjuvant setting has remained largely uncharacterized. In this study, we examine whether Prosigna can identify a subgroup of HER2+ patients for whom
Autor:
Javier Salvador Bofill, Fernando Moreno Anton, Cesar Augusto Rodriguez Sanchez, Elena Galve Calvo, Cristina Hernando Melia, Eva Maria Ciruelos Gil, Maria Vidal, Begoña Jiménez-Rodriguez, Luis De la Cruz Merino, Noelia Martínez Jañez, Rafael Villanueva Vazquez, Ruben de Toro Salas, Antonio Anton Torres, Isabel Manuela Alvarez Lopez, Joaquin Gavila Gregori, Vanesa Quiroga Garcia, Elena Vicente Rubio, Juan De la Haba-Rodriguez, Santiago Gonzalez-Santiago, Nieves Diaz Fernandez, Agusti Barnadas Molins, Blanca Cantos Sanchez de Ibargüen, Juan Ignacio Delgado Mingorance, Meritxell Bellet Ezquerra, Sonia de Casa, Asuncion Gimeno, Miguel Martin
Publikováno v:
Breast, Vol 66, Iss , Pp 77-84 (2022)
Background: Breast cancer is the most common malignancy and the second leading cause of cancer-related mortality in Spanish women. Ribociclib in combination with endocrine therapy (ET) has shown superiority in prolonging survival in patients with hor
Externí odkaz:
https://doaj.org/article/dad241cf2af94fb9adb70457754b6c11
Autor:
Alfonso Alba-Bernal, Rocío Lavado-Valenzuela, María Emilia Domínguez-Recio, Begoña Jiménez-Rodriguez, María Isabel Queipo-Ortuño, Emilio Alba, Iñaki Comino-Méndez
Publikováno v:
EBioMedicine, Vol 62, Iss , Pp 103100- (2020)
Breast cancer is the most common cancer type in women worldwide and its early detection is crucial to curing the disease. Tissue biopsy, currently the method of choice to obtain tumour molecular information, is invasive and might be affected by tumou
Externí odkaz:
https://doaj.org/article/4b5c9fb4fc5f43238fa88923257f0b64
Autor:
Aurora Laborda-Illanes, Lidia Sanchez-Alcoholado, María Emilia Dominguez-Recio, Begoña Jimenez-Rodriguez, Rocío Lavado, Iñaki Comino-Méndez, Emilio Alba, María Isabel Queipo-Ortuño
Publikováno v:
Cancers, Vol 12, Iss 9, p 2465 (2020)
In breast cancer (BC) the employment of sequencing technologies for metagenomic analyses has allowed not only the description of the overall metagenomic landscape but also the specific microbial changes and their functional implications. Most of the
Externí odkaz:
https://doaj.org/article/8177a30d7f7948f7991265730f509f80