Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Begoña Comı́n-Anduix"'
Autor:
Laura E. Martínez, Begoña Comin-Anduix, Miriam Güemes-Aragon, Javier Ibarrondo, Roger Detels, Matthew J. Mimiaga, Marta Epeldegui
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
People living with HIV (PLWH) are at higher risk of developing lymphoma. In this study, we performed cytometry by time-of-flight (CyTOF) on peripheral blood mononuclear cells of cART-naïve HIV+ individuals and cART-naïve HIV+ individuals prior to A
Externí odkaz:
https://doaj.org/article/7edc0f6ea3d44da49a66782c157fb462
Autor:
Daniel Sanghoon Shin, Saroj Basak, Mysore S. Veena, Begoña Comin‐Anduix, Arjun Bhattacharya, Tien S. Dong, Albert Ko, Philip Han, Jonathan Jacobs, Neda A. Moatamed, Luis Avila, Matteo Pellegrini, Marilene Wang, Eri S. Srivatsan
Publikováno v:
Cancer Medicine, Vol 13, Iss 9, Pp n/a-n/a (2024)
Abstract Background A phase I clinical study for patients with locally advanced H&N cancer with a new class of botanical drug APG‐157 provided hints of potential synergy with immunotherapy. We sought to evaluate the efficacy of the combination of A
Externí odkaz:
https://doaj.org/article/2cd20bda95684eefbec527aae61e9d54
Autor:
Arun Singh, Begoña Comin-Anduix, Antoni Ribas, Beata Berent-Maoz, Theodore Scott Nowicki, Luke Frankiw, Cole Peters, Mignonette Macabali, Kiana Shammaie, Crystal Quiros, Paula Kaplan-Lefko, Ignacio Baselga Carretero
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 5 (2023)
Background The tumor antigen NY-ESO-1 has been shown to be an effective target for transgenic adoptive cell therapy (ACT) for the treatment of sarcoma and melanoma. However, despite frequent early clinical responses, many patients ultimately develop
Externí odkaz:
https://doaj.org/article/bdb959ecdff84f8485d422907659729b
Autor:
Giulia Parisi, Justin D. Saco, Felix B. Salazar, Jennifer Tsoi, Paige Krystofinski, Cristina Puig-Saus, Ruixue Zhang, Jing Zhou, Gardenia C. Cheung-Lau, Alejandro J. Garcia, Catherine S. Grasso, Richard Tavaré, Siwen Hu-Lieskovan, Sean Mackay, Jonathan Zalevsky, Chantale Bernatchez, Adi Diab, Anna M. Wu, Begoña Comin-Anduix, Deborah Charych, Antoni Ribas
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Adoptive cell transfer (ACT) of T cells for tumor treatment often requires IL-2 administration. Here, the authors show that a modified IL-2 cytokine (NKTR-214) can outperform IL-2 in a melanoma mouse model.
Externí odkaz:
https://doaj.org/article/26da1a14c88d4cdbbb1ebbe52eeb9731
Autor:
Gloria Yiu, Tue Kruse Rasmussen, Brandon L. Tsai, Vivian K. Diep, David J. Haddon, Jennifer Tsoi, Gopika D. Miller, Begoña Comin-Anduix, Bent Deleuran, Gay M. Crooks, Paul J. Utz
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The establishment of an “interferon (IFN) signature” to subset SLE patients on disease severity has led to therapeutics targeting IFNα. Here, we investigate IFN signaling in SLE using multiplexed protein arrays and single cell cytometry by time
Externí odkaz:
https://doaj.org/article/9c4d59dbaa9c4bd5907b224d9ec6e824
Autor:
Bradley Salvatore, Rachel S. Resop, Brent R. Gordon, Marta Epeldegui, Otoniel Martinez-Maza, Begoña Comin-Anduix, Alex Lam, Ting-Ting Wu, Christel H. Uittenbogaart
Publikováno v:
Cells, Vol 12, Iss 2, p 296 (2023)
Humoral immune response is important in fighting pathogens by the production of specific antibodies by B cells. In germinal centers, T follicular helper (TFH) cells provide important help to B-cell antibody production but also contribute to HIV persi
Externí odkaz:
https://doaj.org/article/0a257bd8f59e4d1b83a1124c06c76197
Autor:
Helena Escuin-Ordinas, Yining Liu, Lu Sun, Willy Hugo, Robert Dimatteo, Rong Rong Huang, Paige Krystofinski, Ariel Azhdam, Jordan Lee, Begoña Comin-Anduix, Alistair J Cochran, Roger S Lo, Tatiana Segura, Philip O Scumpia, Antoni Ribas
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252597 (2021)
Wound healing is a multi-step process to rapidly restore the barrier function. This process is often impaired in diabetic patients resulting in chronic wounds and amputation. We previously found that paradoxical activation of the mitogen-activated pr
Externí odkaz:
https://doaj.org/article/72360e10ae0640ca8f04bc31993c6288
Publikováno v:
BioTechniques, Vol 62, Iss 3, Pp 123-130 (2017)
Peptide–major histocompatibility complex (pMHC) multimers enable the detection, characterization, and isolation of antigen-specific T-cell subsets at the single-cell level via flow cytometry and fluorescence microscopy. These labeling reagents expl
Externí odkaz:
https://doaj.org/article/1a26b447ac5340b8b5b5db3e954125e6
Autor:
Helena Escuin-Ordinas, Shuoran Li, Michael W. Xie, Lu Sun, Willy Hugo, Rong Rong Huang, Jing Jiao, Felipe Meira de-Faria, Susan Realegeno, Paige Krystofinski, Ariel Azhdam, Sara Marie D. Komenan, Mohammad Atefi, Begoña Comin-Anduix, Matteo Pellegrini, Alistair J. Cochran, Robert L. Modlin, Harvey R. Herschman, Roger S. Lo, William H. McBride, Tatiana Segura, Antoni Ribas
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
BRAF inhibitors often show skin-hyperproliferative side effects in melanoma patients. Here, the authors demonstrate that BRAF inhibitors can be used to enhance skin wound healing through the MAPK- ERK pathway activation that positively regulates the
Externí odkaz:
https://doaj.org/article/4df7cfd06ae5433d88273671aa9365b6
Autor:
F Javier Ibarrondo, Otto O Yang, Thinle Chodon, Earl Avramis, Yohan Lee, Hooman Sazegar, Jason Jalil, Bartosz Chmielowski, Richard C Koya, Ingrid Schmid, Jesus Gomez-Navarro, Beth D Jamieson, Antoni Ribas, Begoña Comin-Anduix
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76829 (2013)
A significant barrier to effective immune clearance of cancer is loss of antitumor cytotoxic T cell activity. Antibodies to block pro-apoptotic/downmodulatory signals to T cells are currently being tested. Because invariant natural killer T cells (iN
Externí odkaz:
https://doaj.org/article/86bbe706996e4d22b7abc83500cf3d2b