Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Began, Gopalan"'
Supplementary Methods from Activation of the Fas-FasL Signaling Pathway by MDA-7/IL-24 Kills Human Ovarian Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74f3894d0589af53ba32c0d6d2f93d6b
https://doi.org/10.1158/0008-5472.22364595.v1
https://doi.org/10.1158/0008-5472.22364595.v1
The tumor-suppressive activity of melanoma differentiation–associated gene-7 (mda-7), also known as interleukin 24 (IL-24), has been shown in a spectrum of human cancer cells in vitro and in vivo. However, mechanisms responsible for antitumor activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8664786dfdcfbf2a3732410b7203119c
https://doi.org/10.1158/0008-5472.c.6494268.v1
https://doi.org/10.1158/0008-5472.c.6494268.v1
Autor:
Ito, Isao, Began, Gopalan, Mohiuddin, Imran, Saeki, Tomoyuki, Saito, Yuji, Branch, Cynthia D, Vaporciyan, Ara, Clifton Stephens, L, Yen, Nancy, Roth, Jack A, Ramesh, Rajagopal
Publikováno v:
In Molecular Therapy March 2003 7(3):409-418
Autor:
Began Gopalan, Nandanan Erathodiyil, Shiya Chong, Karthikeyan Narayanan, Andrew C.A. Wan, Jackie Y. Ying
Publikováno v:
Advanced Healthcare Materials. 5:696-701
In highly proliferative cancer cells, energy is predominantly produced by a high rate of glycolysis, followed by lactic acid fermentation, despite the availability of oxygen - an observation known as the Warburg effect. As a consequence, cells employ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a78110af9bdfaafc15603c32d12cdc2
https://doi.org/10.1002/adhm.201500613
https://doi.org/10.1002/adhm.201500613
Autor:
Majad Khan, Yi Yan Yang, Tultul Das, Andrew C.A. Wan, Jane Antony, Began Gopalan, Karthikeyan Narayanan
Publikováno v:
Biotechnology journal. 14(3)
Cationic bolaamphiphile polymers had been previously studied as efficient delivery system for the delivery of proteins with relatively low toxicity. Here, the authors investigate the use of a protein delivery system based on a cationic bolaamphiphile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d543f67317aaedbc3cf5ca885adb832f
https://pubmed.ncbi.nlm.nih.gov/29802765
https://pubmed.ncbi.nlm.nih.gov/29802765
Publikováno v:
Biomaterials. 35:7479-7487
Hepatocellular carcinoma (HCC) is one of the most commonly diagnosed lethal cancers in the world. We previously showed two imidazolium salts (IBN-1 and IBN-9) with a moderate efficacy for HCC. Here we report a more potent imidazolium compound IBN-65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f0299e1bd82fbadc38db44fefd628b7
https://doi.org/10.1016/j.biomaterials.2014.05.022
https://doi.org/10.1016/j.biomaterials.2014.05.022
Publikováno v:
In Food Research International 2000 33(5):341-345
Autor:
Shu Wang, Charlotte A. E. Hauser, Michael R. Reithofer, Mangesh Joshi, Archana Mishra, Began Gopalan, Kiat Hwa Chan, Anupama Lakshmanan, Dang Hoang Lam
Publikováno v:
Chem. Sci.. 5:625-630
Self-assembling ultrashort peptides from aliphatic amino acids were functionalized with platinum anti-cancer drugs by click chemistry. Oxaliplatin-derived hybrid peptide hydrogels with up to 40% drug loading were tested for localized breast cancer th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2068423351d2383abc8a7510f2d95140
https://doi.org/10.1039/c3sc51930a
https://doi.org/10.1039/c3sc51930a
Autor:
Annegret Schumacher, Jackie Y. Ying, Began Gopalan, Shujun Gao, Karthikeyan Narayanan, Daniele Zink, Ming Ni, Farah Tasnim, Karthikeyan Kandasamy, Karl Schumacher
Publikováno v:
Kidney International. 83:593-603
Renal cells are used in basic research, disease models, tissue engineering, drug screening, and in vitro toxicology. In order to provide a reliable source of human renal cells, we developed a protocol for the differentiation of human embryonic stem c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93cdfd2f2bf855e8a268354c5a7fd24c
https://doi.org/10.1038/ki.2012.442
https://doi.org/10.1038/ki.2012.442
Autor:
Nur-Afidah Mohamed Suhaimi, Chunyan Zhang, Siti Nurhanna Riduan, Began Gopalan, Lang Zhuo, Yinling Kng, Yugen Zhang, Zhiyuan Ke
Publikováno v:
Laboratory Investigation. 91:744-751
Imidazolium salts (IMSs) are precursors to N-heterocyclic carbenes (NHCs), which are routinely used as ligands or organo-catalysts in synthetic chemistry. We recently identified several IMSs as anti-fibrotic agents in liver fibrosis, which often has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3017ef876ec6408770d0758f99d59b01
https://doi.org/10.1038/labinvest.2011.4
https://doi.org/10.1038/labinvest.2011.4