Výsledky vyhledávání - "Begüm N. Sağlık"

Design, synthesis, biological activity, molecular docking, and molecular dynamics of novel benzimidazole derivatives as potential AChE/MAO-B dual inhibitors

Autor: Derya Osmaniye, Asaf E. Evren, Begüm N. Sağlık, Serkan Levent, Yusuf Özkay, Zafer A. Kaplancıklı

Publikováno v: Archiv der PharmazieREFERENCES. 355(3)

To develop new acetylcholinesterase (AChE)-monoamine oxidase-B (MAO-B) dual inhibitors against Alzheimer's disease, the benzimidazole ring, which has a propargyl side chain with previously proven selective MAO-B inhibitory activity, was used as the m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeeb37462511d2689535ce4ffa5c44e2
https://pubmed.ncbi.nlm.nih.gov/34931332

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Synthesis, anticholinesterase activity, molecular docking, and molecular dynamic simulation studies of 1,3,4‐oxadiazole derivatives

Autor: Şeyma Durmaz, Asaf E. Evren, Begüm N. Sağlık, Leyla Yurttaş, Naime F. Tay

Publikováno v: Archiv der Pharmazie. 355:2200294

Two new series of 1,3,4-oxadiazoles bearing pyridine and thiazole heterocycles (4a-h and 5a-h) were synthesized (2,5-disubstituted-1,3,4-oxadiazoles). The structures of these newly synthesized compounds were confirmed by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714cbf3521cc3f9964a6a283b9dde80a
https://doi.org/10.1002/ardp.202200294

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