In Silico ADME Screening and Evaluation of Antimicrobial and Antimycobacterial Activities of 3,5-Diphenyl Pyrazoline Derivatives

Autor: Erkan Aksoz, Begüm Evranos Aksöz, Selda Özgen, Fatma Kaynak Kaynak Onurdağ

Publikováno v: Volume: 12, Issue: 2 184-191
Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi

Objective: The unconscious widespread use of antibiotics leads to the development of resistance to antibiotics. When resistance to an antibiotic develops, it now either shows less efficacy or loses its effect completely at that antibiotic treatment d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e2ee1eee8d5725cf6d0ff4275c743b5
https://doi.org/10.22312/sdusbed.872130

Investigation of Antimicrobial and Antitubercular Activities of Some Hydrazone Derived Compounds

Autor: Erkan Aksoz, Selda Özgen, Fatma Kaynak Kaynak Onurdağ, Begüm Evranos Aksöz

Publikováno v: Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi, Vol 24, Iss 1, Pp 196-200 (2020)
Volume: 24, Issue: 1 196-200
Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi

Bir seri hidrazon türevi, antifungal, antimikrobiyal ve antitüberküler etkilerini araştırmak için sentezlendi. Bileşiklerin bu etkileri, Escherichia coli, Escherichia coli izolat (ESBL), Pseudomonas aeruginosa, Pseudomonas aeruginosa izolat (g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64fd56b81743753a81f633014a8c3a47
https://doi.org/10.19113/sdufenbed.672554

Vital Role of Monoamine Oxidases and Cholinesterases in Central Nervous System Drug Research: A Sharp Dissection of the Pathophysiology

Autor: Erkan Aksoz, Begüm Evranos Aksöz

Publikováno v: Combinatorial chemistryhigh throughput screening. 23(9)

Background: Monoamine oxidase and cholinesterase enzymes are very critical enzymes that regulate the level of neurotransmitters such as acetylcholine and monoamines. Monoamine neurotransmitters and acetylcholine play a very important role in many phy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a57aeb5386090e68047c3b39b7061f20
https://pubmed.ncbi.nlm.nih.gov/32077819

Synthesis and Screening of Human Monoamine Oxidase-A Inhibitor Effect of New 2-Pyrazoline and Hydrazone Derivatives

Autor: Teodora Djikic, Kemal Yelekçi, Begüm Evranos-Aksöz, Samiye Yabanoglu-Ciftci, Gulberk Ucar, Rahmiye Ertan, Ipek Baysal

Publikováno v: Archiv der Pharmazie. 348:743-756

A group of 3,5-diaryl-2-pyrazoline and hydrazone derivatives was prepared via the reaction of various chalcones with hydrazide compounds in ethanol. Twenty original compounds were synthesized. Ten of these original compounds have a pyrazoline structu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8dba6bd947dde62fe120455c56c1bbee
https://doi.org/10.1002/ardp.201500212

Design, Synthesis and hMAO Inhibitory Screening of Novel 2-Pyrazoline Analogues

Autor: Begüm Evranos-Aksöz, Kemal Yelekçi, Gulberk Ucar

Aim and Objective: MAO inhibitors have a significant effect on the nervous system since they act in regulation of neurotransmitter concentrations. Neurotransmitter levels are critical for a healthy nervous system. MAO inhibitors can be used in the tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c68ec053cd5913269fbb186c82c0834
https://hdl.handle.net/20.500.12469/3472