Gonococcal Mimitope Vaccine Candidate Forms a Beta-Hairpin Turn and Binds Hydrophobically to a Therapeutic Monoclonal Antibody.

Autor: Beernink PT; Department of Pediatrics, University of California San Francisco, 5700 Martin Luther King Jr. Way, Oakland, California 94609, United States., Di Carluccio C; Department of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Naples, Italy., Marchetti R; Department of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Naples, Italy., Cerofolini L; Department of Chemistry, University of Florence, Via della Lastruccia 13, 50019 Sesto Fiorentino, Italy., Carillo S; National Institute for Bioprocessing Research and Training, Foster Avenue, Mount Merrion, Blackrock, Co., Dublin A94 X099, Ireland., Cangiano A; Department of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Naples, Italy., Cowieson N; Diamond Light Source, Didcot, OX11 0DE Oxfordshire, England, United Kingdom., Bones J; National Institute for Bioprocessing Research and Training, Foster Avenue, Mount Merrion, Blackrock, Co., Dublin A94 X099, Ireland.; School of Chemical and Bioprocess Engineering, University College Dublin, Belfield Dublin 4, Ireland., Molinaro A; Department of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Naples, Italy., Paduano L; Department of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Naples, Italy., Fragai M; Department of Chemistry, University of Florence, Via della Lastruccia 13, 50019 Sesto Fiorentino, Italy., Beernink BP; Department of Pediatrics, University of California San Francisco, 5700 Martin Luther King Jr. Way, Oakland, California 94609, United States., Gulati S; Department of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, 364 Plantation St, Worcester, Massachusetts 01605, United States., Shaughnessy J; Department of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, 364 Plantation St, Worcester, Massachusetts 01605, United States., Rice PA; Department of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, 364 Plantation St, Worcester, Massachusetts 01605, United States., Ram S; Department of Infectious Diseases and Immunology, University of Massachusetts Chan Medical School, 364 Plantation St, Worcester, Massachusetts 01605, United States., Silipo A; Department of Chemical Sciences, University of Naples Federico II, Via Cintia 4, 80126 Naples, Italy.

Publikováno v: JACS Au [JACS Au] 2024 Jul 05; Vol. 4 (7), pp. 2617-2629. Date of Electronic Publication: 2024 Jul 05 (Print Publication: 2024).