Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Beena T. Koshy"'
Autor:
Vincent Mooser, Lon R. Cardon, Chun-Fang Xu, Zhengyu Xue, Lini Pandite, Brian H. Reck, Colin F. Spraggs, Lingkang Huang, Beena T. Koshy, Vicki L. Goodman, Michael R. Barnes
Publikováno v:
Journal of Hepatology. 54:1237-1243
Background & Aims Pazopanib has demonstrated clinical benefit in patients with advanced renal cell carcinoma (RCC) and is generally well tolerated. However, transaminase elevations have commonly been observed. This 2-stage study sought to identify ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81a81e3511b78ab25762f4e265170ee
https://doi.org/10.1016/j.jhep.2010.09.028
https://doi.org/10.1016/j.jhep.2010.09.028
Autor:
Pamela L. St. Jean, Ryozo Kuwano, Heide Stirnadel, Justin P. Rubio, Michael C. Irizarry, Toshihiko Kaise, Vincent Mooser, Beena T. Koshy, Akinori Miyashita
Publikováno v:
Journal of Alzheimer's Disease. 21:775-780
High plasma lipoprotein phospholipase A2 activity (Lp-PLA2) is reported to be a risk factor for dementia. A loss of function polymorphism in the Lp-PLA2 gene - PLA2G7 V279F - is found almost exclusively in Asians. In 1,952 subjects with late-onset AD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b61bdd69b05a0e75faf02c1bc4966e
https://doi.org/10.3233/jad-2010-100513
https://doi.org/10.3233/jad-2010-100513
Autor:
Kara Helin, Ivan A. Klement, Antonio Servadio, Harry T. Orr, Pamela J. Skinner, Christopher J. Cummings, Huda Y. Zoghbi, Beena T. Koshy
Publikováno v:
Nature. 389:971-974
Spinocerebellar ataxia type 1 (SCA1) is one of several neurodegenerative disorders caused by an expansion of a polyglutamine tract. It is characterized by ataxia, progressive motor deterioration, and loss of cerebellar Purkinje cells. To understand t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b5f5e935936413fb5e3d09b2057bfc
https://doi.org/10.1038/40153
https://doi.org/10.1038/40153
Autor:
Huda Y. Zoghbi, Beena T. Koshy
Publikováno v:
Brain Pathol
In the past few years, a new type of genetic mutation, expansion of trinucleotide repeats, has been shown to cause neurologic disease. This new class of mutations was first identified in 1991 as the underlying genetic defect in spinal and bulbar musc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2802616973cb5ef2f93bd154ba32fd6f
https://doi.org/10.1111/j.1750-3639.1997.tb00894.x
https://doi.org/10.1111/j.1750-3639.1997.tb00894.x
Autor:
Jennifer D. Davidson, Huda Y. Zoghbi, Beena T. Koshy, Eric N. Burright, Lisa A. Duvick, Harry T. Orr
Publikováno v:
Human Molecular Genetics. 6:513-518
Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disorder caused by the expansion of a polyglutamine tract within the SCA1 gene product, ataxin-1. Expansion of this tract is believed to result in a gain of function by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6aa94092060b084b5ac3afa4f3ba8a9
https://doi.org/10.1093/hmg/6.4.513
https://doi.org/10.1093/hmg/6.4.513
Autor:
Michael Mosteller, Hector Ortega, Lynn D. Condreay, Lingkang Huang, Sandra W. Stinnett, Beena T. Koshy, Wayne Anderson
Publikováno v:
Annals of allergy, asthmaimmunology : official publication of the American College of Allergy, Asthma,Immunology. 110(6)
Identifying genetic markers of susceptibility to exacerbations may improve patient management, decrease morbidity, and lead to drug development.To assess whether genetic markers associated with severe asthma exacerbations in previous reports are asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f9b790a0e2029b7e7c7d81bff2517d
https://pubmed.ncbi.nlm.nih.gov/23706709
https://pubmed.ncbi.nlm.nih.gov/23706709
Autor:
Beena T. Koshy, Eric N. Burright, Harry T. Orr, Kenneth H. Fischbeck, Huda Y. Zoghbi, Toni Matilla, Diane E. Merry
Publikováno v:
Human Molecular Genetics. 5:1311-1318
Spinocerebellar ataxia type1 (SCA1) is one of several neurodegenerative disorders caused by expansions of translated CAG trinucleotide repeats which code for polyglutamine in the respective proteins. Most hypotheses about the molecular defect in thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52bf08d06e3d9c353df0319dd129a136
https://doi.org/10.1093/hmg/5.9.1311
https://doi.org/10.1093/hmg/5.9.1311
Autor:
Dawna L. Armstrong, Harry T. Orr, Beena T. Koshy, Antonio Servadio, Huda Y. Zoghbi, Barbara Antalffy
Publikováno v:
Nature Genetics. 10:94-98
Spinocerebellar ataxia type 1 (SCA1) is an autosomal dominant neurodegenerative disorder caused by expansion of a CAG trinucleotide repeat which codes for glutamine in the protein ataxin-1. We have investigated the effect of this expansion on ataxin-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a11e42717d8b9b655f295f02e2fefbc9
https://doi.org/10.1038/ng0595-94
https://doi.org/10.1038/ng0595-94
Autor:
Michael J. Ackerman, Matthew L. Anderson, Felicita Andreotti, Brian H. Annex, Anthony Antonellis, Dmitri Artemov, James R. Bain, Peter J. Barnes, J.S. Barnholtz-Sloan, Richard C. Becker, Ivor J. Benjamin, Paul R. Billings, Simon C. Body, Mark Boguski, Stefano Bonassi, Brigitta Bondy, J. Martijn Bos, Roger E. Breitbart, Jerome Brody, Matthew P. Brown, Lars Bullinger, Shawn C. Burgess, Atul J. Butte, David J. Carey, George Carlson, Juan C. Celedón, Subhashini Chandrasekharan, Wing C. (John) Chang, Yan Chen, Antonio Chiocca, Theresa Puifun Chow, Wendy K. Chung, Robert Cook-Deegan, Dolores Corella, Susan Cottrell, Nancy J. Cox, Nigel P.S. Crawford, A. Jamie Cuticchia, Dieter Deforce, Mario C. Deng, Gayathri Devi, Theo deVos, Juergen Distler, Harmut Dohner, Ayotunde O. Dokun, Mark R. Edbrooke, Lucas B. Edelman, Dirk Elewaut, Charles J. Epstein, Ayman H. Fanous, Phillip G. Febbo, Robert J. Feezor, Yonmei Feng, Zeno Földes-Papp, Hidehiko Fujinaka, David J. Galas, Louis, P. Garrison, Glenn S. Gerhard, Geoffrey S. Ginsburg, Bjorn T. Gjertsen, Michael Glass, David B. Goldstein, Erynn S. Gordon, Tucker Gosnell, Peter Grass, Eric D. Green, Iris Grossman, Marta Gwinn, Carolina Haefliger, Susanne B. Haga, Per Hall, Joshua M. Hare, Ahmad Hariri, James R. Heath, Robert A. Hegele, Bettina Heidecker, Shona Hislop, Eric P. Hoffman, John Holton, Leroy Hood, Andrew T. Huang, Erich S. Huang, Carlos A. Hubbard, Kent Hunter, Courtney Hyland, Chunhwa Ihm, Olga Ilkayeva, Rafael Irizarry, Shushant Jain, Melissa D. Johnson, Philip W. Kantoff, Sekar Kathiresan, Hasmeena Kathuria, Kensaku Kawamoto, Filip De Keyser, Asif Khalid, Muin Khoury, Stephen F. Kingsmore, Michelle M. Kittleson, Beena T. Koshy, Ranga Krishnan, Robert S. Krouse, Vikas Kundra, Myla Lai-Goldman, Vipul Lakhani, Robert Langer, Sean E. Lawler, Inyoul Lee, Charles Lee, Arthur S. Lee, Stanely Leong, Ralf Lesche, Samuel Levy, Edison T. Liu, David F. Lobach, James B. Lorens, Aldons J. Lusis, H. Kim Lyerly, Nageswara R. Madamanchi, J. Alfredo Martinez, Vega Masignani, Kevin McGrath, John McHutchison, Frank Middleton, Herman Mielants, Michael J. Muehlbauer, Ulf Müller-Ladner, Mark A. Nelson, Monica Neri, Mihai Netea, L. Kristin Newby, Christopher B. Newgard, Maggie Ng, Paul W. Noble, Vasilis Ntziachristos, Robert L. Nussbaum, Meghan B. O'Donoghue, Kunle Odunsi, Kenneth Olden, Steve R. Ommen, Jose M. Ordovas, Roberto Patarca, Jeetendra Patel, K. Patel, Carlos N. Pato, Michele T. Pato, Tanja Pejovic, Noah C. Perin, Michael Pham, Robert M. Plenge, Achim Plum, Mihai V. Podgoreanu, Jonathan R. Pollack, Rebecca L. Pollex, Nathan D. Price, Thomas Quertermous, Francisco J. Quintana, Benjamin A. Raby, Daniel J. Rader, Sridhar Ramaswamy, Hans-Georg Rammensee, Scott D. Ramsey, Rino Rappuoli, Nader Rifai, Lisa Rimsza, Yu-Hui Rogers, Allen D. Roses, Jeffrey S. Ross, Ronenn Roubenoff, Marschall S. Runge, Maren T. Scheuner, Matthias Schuster, David A. Schwartz, Debra A. Schwinn, Chia Kee Seng, Nicholas A. Shackel, M. Frances Shannon, A. Dean Sherry, Jiaqi Shi, Kevin Shianna, Yelizaveta Shnayder, Andrew B. Singleton, T.P. Slavin, Desmond J. Smith, Rikkert L. Snoeckx, Ralph Snyderman, Avrum Spira, Colin F. Spraggs, Robert D. Stevens, Nicolas A. Stewart, Alison Stewart, F. Stewart, Robert L. Strausberg, Moshe Szyf, Weihong Tan, Robert I. Tepper, Hervé Tettelin, Giovana R. Thomas, John D. Thompson, Visith Thongboonkerd, Eric J. Topol, Jeffrey A. Towbin, Ad A. van Bodegraven, Kris Van Den Bogaert, Filip Van den Bosch, Matte Vatta, Timothy D. Veenstra, David L. Veenstra, Aleksandr E. Vendrov, Catherine M. Verfaillie, Nicole M. Walley, Ling Wang, Mike Weale, Michael E. Weinblatt, Howard L. Weiner, Scott T. Weiss, Ralph Weissleder, Samuel A. Wells, Brett R. Wenner, Ilse R. Wiechers, Georgia L. Wiesner, Janey L. Wiggs, Cisca Wijmenga, Huntington F. Willard, James M. Wilson, Nelson A. Wivel, Jay Wohlgemuth, Janet Woodcock, Christopher W. Woods, Paula W. Woon, Chana Yagil, Yoram Yagil, Tadashi Yamamoto, Gang Yao, Andrew J. Yee, Hyuntae Yoo, Y. Nancy You, Li-Rong Yu, Jean-François Zagury, Ron Zimmern, Stephan Züchner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::367a8db2d410089a2fbc70873f53c292
https://doi.org/10.1016/b978-0-12-369420-1.00122-0
https://doi.org/10.1016/b978-0-12-369420-1.00122-0
