Zobrazeno 1 - 10
of 353
pro vyhledávání: '"Beena, E"'
Autor:
Hope L. Mumme, Sunil S. Raikar, Swati S. Bhasin, Beena E. Thomas, Taylor Lawrence, Elizabeth P. Weinzierl, Yakun Pang, Deborah DeRyckere, Chuck Gawad, Daniel S. Wechsler, Christopher C. Porter, Sharon M. Castellino, Douglas K. Graham, Manoj Bhasin
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-25 (2023)
Abstract Background Mixed phenotype acute leukemia (MPAL), a rare subgroup of leukemia characterized by blast cells with myeloid and lymphoid lineage features, is difficult to diagnose and treat. A better characterization of MPAL is essential to unde
Externí odkaz:
https://doaj.org/article/27b0d44d90b644919eac2539e49cde72
Autor:
Hope Mumme, Beena E. Thomas, Swati S. Bhasin, Upaasana Krishnan, Bhakti Dwivedi, Pruthvi Perumalla, Debasree Sarkar, Gulay B. Ulukaya, Himalee S. Sabnis, Sunita I. Park, Deborah DeRyckere, Sunil S. Raikar, Melinda Pauly, Ryan J. Summers, Sharon M. Castellino, Daniel S. Wechsler, Christopher C. Porter, Douglas K. Graham, Manoj Bhasin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Acute myeloid leukemia (AML) microenvironment exhibits cellular and molecular differences among various subtypes. Here, we utilize single-cell RNA sequencing (scRNA-seq) to analyze pediatric AML bone marrow (BM) samples from diagnosis (Dx),
Externí odkaz:
https://doaj.org/article/a3787863b5cb43ff9dcb50ae8a436b4d
Autor:
Swati S. Bhasin, Beena E. Thomas, Ryan J. Summers, Debasree Sarkar, Hope Mumme, William Pilcher, Mohamed Emam, Sunil S. Raikar, Sunita I. Park, Sharon M. Castellino, Douglas K. Graham, Manoj K. Bhasin, Deborah DeRyckere
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Different driver mutations and/or chromosomal aberrations and dysregulated signaling interactions between leukemia cells and the immune microenvironment have been implicated in the development of T-cell acute lymphoblastic leukemia (T-ALL).
Externí odkaz:
https://doaj.org/article/bad7ef4e0fc14a73bb94f1c5d3d5576c
Autor:
Sarthak Satpathy, Beena E. Thomas, William J. Pilcher, Mojtaba Bakhtiari, Lori A. Ponder, Rafal Pacholczyk, Sampath Prahalad, Swati S. Bhasin, David H. Munn, Manoj K. Bhasin
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionCurrent multistep methods utilized for preparing and cryopreserving single-cell suspensions from blood samples for single-cell RNA sequencing (scRNA-seq) are time-consuming, requiring trained personnel and special equipment, so limiting t
Externí odkaz:
https://doaj.org/article/20be76746b6a40eebb3954e9418e477a
Autor:
Ramya Ganesan, Swati S Bhasin, Mojtaba Bakhtiary, Upaasana Krishnan, Nagarjuna R Cheemarla, Beena E Thomas, Manoj K Bhasin, Vikas P Sukhatme
Publikováno v:
PLoS Biology, Vol 21, Iss 9, p e3002275 (2023)
A major cause of cancer recurrence following chemotherapy is cancer dormancy escape. Taxane-based chemotherapy is standard of care in breast cancer treatment aimed at killing proliferating cancer cells. Here, we demonstrate that docetaxel injures str
Externí odkaz:
https://doaj.org/article/6859078ccfb9422a941de4b39a3b32a9
Akademický článek
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Autor:
Ranjan Kumar Prusty, Ragini Kulkarni, Priyanka Gawai, Gajanan Velhal, Deepika Sadawarte, Swapnil Kharnare, Beena E Thomas, Geetha Menon, Sumit Aggarwal, Tapas Chakma
Publikováno v:
Journal of Mental Health and Human Behaviour, Vol 28, Iss 1, Pp 78-87 (2023)
Background: The unprecedented onset of coronavirus disease 2019 (COVID-19) had a huge impact on health-care facilities, leading to different psychosocial challenges among health-care workers (HCWs) during this pandemic. Aim: This study aimed to explo
Externí odkaz:
https://doaj.org/article/e3ffb8a307e44257b52565b0c45d95fc
Autor:
William Pilcher, Beena E. Thomas, Swati S. Bhasin, Reyka G. Jayasinghe, Lijun Yao, Edgar Gonzalez-Kozlova, Surendra Dasari, Seunghee Kim-Schulze, Adeeb Rahman, Jonathan Patton, Mark Fiala, Giulia Cheloni, Taxiarchis Kourelis, Madhav V. Dhodapkar, Ravi Vij, Shaadi Mehr, Mark Hamilton, Hearn Jay Cho, Daniel Auclair, David E. Avigan, Shaji K. Kumar, Sacha Gnjatic, Li Ding, Manoj Bhasin
Publikováno v:
npj Genomic Medicine, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Despite advancements in understanding the pathophysiology of Multiple Myeloma (MM), the cause of rapid progressing disease in a subset of patients is still unclear. MM’s progression is facilitated by complex interactions with the surroundi
Externí odkaz:
https://doaj.org/article/5ec9d6ffad3147ae897b03780c2b90aa
Autor:
Bhasin, Swati S.1,2 (AUTHOR) swati.sharma.bhasin@emory.edu, Thomas, Beena E.1,2 (AUTHOR), Summers, Ryan J.1,2 (AUTHOR), Sarkar, Debasree1,3 (AUTHOR), Mumme, Hope1,3 (AUTHOR), Pilcher, William4 (AUTHOR), Emam, Mohamed2 (AUTHOR), Raikar, Sunil S.1,2 (AUTHOR), Park, Sunita I.5 (AUTHOR), Castellino, Sharon M.1,2 (AUTHOR), Graham, Douglas K.1,2 (AUTHOR), Bhasin, Manoj K.1,2,3,4 (AUTHOR), DeRyckere, Deborah1,2 (AUTHOR)
Publikováno v:
Scientific Reports. 8/2/2023, Vol. 13 Issue 1, p1-16. 16p.
Autor:
Georgios Theocharidis, Beena E. Thomas, Debasree Sarkar, Hope L. Mumme, William J. R. Pilcher, Bhakti Dwivedi, Teresa Sandoval-Schaefer, Ruxandra F. Sîrbulescu, Antonios Kafanas, Ikram Mezghani, Peng Wang, Antonio Lobao, Ioannis S. Vlachos, Biraja Dash, Henry C. Hsia, Valerie Horsley, Swati S. Bhasin, Aristidis Veves, Manoj Bhasin
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Diabetic foot ulcers (DFUs) remain a complication of diabetes that are difficult to heal and lead to disability. Here the authors use single-cell RNA-sequencing and spatial transcriptomics to characterize the DFU cellular landscape and identify a pop
Externí odkaz:
https://doaj.org/article/f9eeb6aeee15457486ee4ea3a39b9697