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Publikováno v:
In Osteoarthritis and Cartilage 2002 10(10):758-767
Publikováno v:
Annals of the New York Academy of Sciences, 878, 150-158
Elevated MMP activities are implicated in tissue degradation in, e.g., arthritis and cancer. The present study was designed to measure MMP enzyme activity in plasma. Free active MMP is unlikely to be present in plasma: upon entering the circulation,
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Publikováno v:
Fibrinolysis and proteolysis, Suppl. 1, 13, 41
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Publikováno v:
Osteoarthritis and Cartilage, 5, 6, 330-340
Objective: To determine the role of interleukin-1β (IL-1β) in the degradation of proteoglycans and collagen by articular chondrocytes. Design: Chondrocytes were cultured in alginate beads for 2 weeks to produce extracellular matrix, followed by the
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Autor:
Valburg, A.A. van, Wenting, M.J.G., Beekman, B., TeKoppele, J.M., Lafeber, F.P.G.J., Bijlsma, J.W.J.
Publikováno v:
Journal of rheumatology, 2, 24, 358-364
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Publikováno v:
FEBS Letters, 3, 418, 305-309
Stromelysin-1 (MMP-3) is an important member of the matrix metalloproteinase family. In joint-degrading diseases like arthritis, elevated levels of MMP-3 protein are detected in synovial fluid using immunological methods. However, these methods do no
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Publikováno v:
FEBS letters, 390, 221-225
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Publikováno v:
Analytical biochemistry, 240, 167-176
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