Predicting the safety of medicines in pregnancy: A workshop report.

Autor: Clements JM; Medicines and Healthcare products Regulatory Agency, London, UK., Hawkes RG; Medicines and Healthcare products Regulatory Agency, London, UK. Electronic address: ross.hawkes@mhra.gov.uk., Jones D; Medicines and Healthcare products Regulatory Agency, London, UK., Adjei A; Medicines and Healthcare products Regulatory Agency, London, UK., Chambers T; Medicines and Healthcare products Regulatory Agency, London, UK., Simon L; Medicines and Healthcare products Regulatory Agency, London, UK., Stemplewski H; Medicines and Healthcare products Regulatory Agency, London, UK., Berry N; National Institute for Biological Standards and Control, Potters Bar, UK., Price S; University of Surrey, UK., Pirmohamed M; University of Liverpool, UK., Piersma AH; National Institute for Public Health and the Environment (RIVM), Center for Health Protection, Bilthoven, Netherlands., Waxenecker G; Austrian Medicines and Medical Devices Agency, Vienna, Austria., Barrow P; Roche Pharmaceutical Research and Early Development, Basel, Switzerland., Beekhuijzen MEW; Charles River,' s-Hertogenbosch, Netherlands., Fowkes A; Lhasa Limited, Leeds, UK., Prior H; National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), London, UK., Sewell F; National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs), London, UK.

Publikováno v: Reproductive toxicology (Elmsford, N.Y.) [Reprod Toxicol] 2020 Apr; Vol. 93, pp. 199-210. Date of Electronic Publication: 2020 Feb 29.

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FGTN: Fragment-based graph transformer network for predicting reproductive toxicity.

Autor: Ren JN; College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Rd., Hangzhou, 310058, Zhejiang, China., Chen Q; College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Rd., Hangzhou, 310058, Zhejiang, China., Ye HY; College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Rd., Hangzhou, 310058, Zhejiang, China., Cao C; College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Rd., Hangzhou, 310058, Zhejiang, China.; Polytechnic Institute, Zhejiang University, 269 Shixiang Rd., Hangzhou, 310015, Zhejiang, China., Guo YM; College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Rd., Hangzhou, 310058, Zhejiang, China., Yang JR; College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Rd., Hangzhou, 310058, Zhejiang, China.; Polytechnic Institute, Zhejiang University, 269 Shixiang Rd., Hangzhou, 310015, Zhejiang, China., Wang H; College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Rd., Hangzhou, 310058, Zhejiang, China., Khan MZI; College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Rd., Hangzhou, 310058, Zhejiang, China., Chen JZ; College of Pharmaceutical Sciences, Zhejiang University, 866 Yuhangtang Rd., Hangzhou, 310058, Zhejiang, China. chjz@zju.edu.cn.

Publikováno v: Archives of toxicology [Arch Toxicol] 2024 Dec; Vol. 98 (12), pp. 4077-4092. Date of Electronic Publication: 2024 Sep 18.

Human health screening level risk assessments of tertiary-butyl acetate (TBAC): Calculated acute and chronic reference concentration (RfC) and Hazard Quotient (HQ) values based on toxicity and exposure scenario evaluations.

Autor: Bus, James S.¹ (AUTHOR) jbus@exponent.com, Banton, Marcy I.² (AUTHOR), Faber, Willem D.³ (AUTHOR), Kirman, Christopher R.⁴ (AUTHOR), McGregor, Douglas B.⁵ (AUTHOR), Pourreau, Daniel B.² (AUTHOR)

Publikováno v: Critical Reviews in Toxicology. Feb2015, Vol. 45 Issue 2, p142-171. 30p. 1 Diagram, 13 Charts, 3 Graphs.

CORRESPONDENCE.

Publikováno v: Lancet. 2/10/2001, Vol. 357 Issue 9254, p472. 11p. 1 Chart, 2 Graphs.