Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Bee Leng Lee"'
Publikováno v:
Stat Biosci
A curve-free, Bayesian decision-theoretic two-stage design is proposed to select biological efficacious doses (BEDs) for phase Ia/Ib trials in which both toxicity and efficacy signals are observed. No parametric models are assumed to govern the dose-
Autor:
Steve Crunk, Scott McGarvie, Alan J. Salzberg, Bee Leng Lee, Peter J. Kempthorne, William B. Fairley, Julie Novak
Publikováno v:
The American Statistician. 71:249-258
The City of New York negotiated a dispute over the performance of new garbage trucks purchased from a vehicle manufacturer. The dispute concerned the fulfillment of a specification in the p...
Publikováno v:
Epidemiol Infect
SUMMARYPrevalence of vancomycin-resistant enterococci (VRE) and use of daptomycin are increasing in Asia. To determine the prevalence of daptomycin non-susceptible enterococci (DNSE) and understand factors associated with reduced daptomycin susceptib
Publikováno v:
Pathology. 48:288-290
Publikováno v:
Journal of biopharmaceutical statistics. 27(1)
Although Bayesian statistical methods are gaining attention in the medical community, as they provide a natural framework for incorporating prior information, the complexity of these methods limited their adoptions in clinical trials. This article pr
Autor:
Bee Leng Lee, Shenghua Kelly Fan
Publikováno v:
Journal of Biopharmaceutical Statistics. 22:802-818
Existing algorithms for identifying the maximum tolerated combination in dose-finding trials of two agents are mostly one-dimensional. Moreover, these algorithms use only the frequency of observed dose-limiting toxicities as the basis for dose escala
Publikováno v:
Journal of the American Statistical Association. 100:960-969
We consider frequentist inference for the parametric component θ separately from the nuisance parameter η in semiparametric models based on sampling from the posterior of the profile likelihood. We prove that this procedure gives a first-order–co
Publikováno v:
Annals of the Institute of Statistical Mathematics. 57:255-277
This paper introduces the “piggyback bootstrap.” Like the weighted bootstrap, this bootstrap procedure can be used to generate random draws that approximate the joint sampling distribution of the parametric and nonparametric maximum likelihood es
Autor:
Bee Leng Lee, Jason Fine
Publikováno v:
Encyclopedia of Biopharmaceutical Statistics ISBN: 1439822468
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::895252cbf76c7c940731408f8e918375
https://doi.org/10.3109/9781439822463.175
https://doi.org/10.3109/9781439822463.175
Autor:
Karen Fink, Michael D. Prados, Timothy F. Cloughesy, H. Ian Robins, Susan M. Chang, Bee Leng Lee, Nicholas Butowski, Lauren E. Abrey, Lisa M. DeAngelis, Frank S. Lieberman, Minesh P. Mehta, Kathleen R. Lamborn, Larry Junck, Andres M. Salazar
This phase II study was designed to determine the objective response rate and 6-month progression free survival of adult patients with recurrent supratentorial anaplastic glioma when treated with the immune modulator, polyinosinic-polycytidylic acid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e057879de7b4a98609747f9b45e4a15
https://europepmc.org/articles/PMC3104130/
https://europepmc.org/articles/PMC3104130/