Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Bee Kheng Ng"'
Autor:
Jeanette M. Wood, Brian Dymock, Mathew Garnett, Ultan McDermott, Cyril Benes, Boon Cher Goh, Nurulhuda Mustafa, Wee Joo Chng, Kantharaj Ethirajulu, Khalid M. Pasha, Ramesh Jayaraman, Harish Nagaraj, Babita Madan, Chithra Amalini, Bee Kheng Ng, Albert Cheong, Lai Chun Ong, Yong Cheng Tan, Meredith Williams, Kee Chuan Goh, Veronica Novotny-Diermayr, Stefan Hart
PDF file - 2.9MB, In-vitro kinase assay, Histology, Cell proliferation, MANOVA analysis for genomic correlates of drug sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ecb3048e6ff5affcb194a51978b5d1
https://doi.org/10.1158/1535-7163.22497421
https://doi.org/10.1158/1535-7163.22497421
Autor:
Jeanette M. Wood, Brian Dymock, Mathew Garnett, Ultan McDermott, Cyril Benes, Boon Cher Goh, Nurulhuda Mustafa, Wee Joo Chng, Kantharaj Ethirajulu, Khalid M. Pasha, Ramesh Jayaraman, Harish Nagaraj, Babita Madan, Chithra Amalini, Bee Kheng Ng, Albert Cheong, Lai Chun Ong, Yong Cheng Tan, Meredith Williams, Kee Chuan Goh, Veronica Novotny-Diermayr, Stefan Hart
Dysregulation of the PI3K/mTOR pathway, either through amplifications, deletions, or as a direct result of mutations, has been closely linked to the development and progression of a wide range of cancers. Moreover, this pathway activation is a poor p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::389efae3908c20bd53e37aa050195e71
https://doi.org/10.1158/1535-7163.c.6535609
https://doi.org/10.1158/1535-7163.c.6535609
Autor:
Jeanette M. Wood, Brian Dymock, Mathew Garnett, Ultan McDermott, Cyril Benes, Boon Cher Goh, Nurulhuda Mustafa, Wee Joo Chng, Kantharaj Ethirajulu, Khalid M. Pasha, Ramesh Jayaraman, Harish Nagaraj, Babita Madan, Chithra Amalini, Bee Kheng Ng, Albert Cheong, Lai Chun Ong, Yong Cheng Tan, Meredith Williams, Kee Chuan Goh, Veronica Novotny-Diermayr, Stefan Hart
PDF file - 663K, Ambit kinome tree, Cell proliferation data, Pharmacokinetics, Body weight changes in PC3 efficacy study, Active vessel stain in COLO-205 efficacy study, MV4-11 efficacy model, Drug sensitivity profiling and correlation to mutation st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407e7e397fec9712aed4f01696117bc4
https://doi.org/10.1158/1535-7163.22497424
https://doi.org/10.1158/1535-7163.22497424
Autor:
Jeanette M. Wood, Brian Dymock, Mathew Garnett, Ultan McDermott, Cyril Benes, Boon Cher Goh, Nurulhuda Mustafa, Wee Joo Chng, Kantharaj Ethirajulu, Khalid M. Pasha, Ramesh Jayaraman, Harish Nagaraj, Babita Madan, Chithra Amalini, Bee Kheng Ng, Albert Cheong, Lai Chun Ong, Yong Cheng Tan, Meredith Williams, Kee Chuan Goh, Veronica Novotny-Diermayr, Stefan Hart
XLS file - 167K, Table 1: Cell line drug sensitivity data for SB2343 and mutations in cancer genes. Table 2: Results from MANOVA analysis of cancer genes as modifiers of drug sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794bb76ff68be2e6a52cec2e5c03efb5
https://doi.org/10.1158/1535-7163.22497418
https://doi.org/10.1158/1535-7163.22497418