Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Bee Hui Liu"'
Autor:
May Yin Lee, Zhi Han Lim, Yun Shen Chan, Feng Li, Atsushi Suzuki, Edward Kai-Hua Chow, Glenn Kunnath Bonney, John M. Asara, Alicia Stein, Matan Thangavelu Thangavelu, Yoganathan Kanagasundaram, Tan Boon Toh, Guo-Dong Lu, Joanna Z. Yeo, Hong Kee Tan, Kol Jia Yong, Siyu Wang, Justin L. Tan, Chung Yan Leong, Yock Young Dan, Chan Shuo Wu, Giridharan Periyasamy, Zi Hui Tan, Bee Hui Liu, Siming Ma, Wai Leong Tam, Huck-Hui Ng, Guo Hao Ng, Siew Bee Ng, Lissa Hooi, Nikki R. Kong, Tim Chan, Daniel G. Tenen, Li Chai, Kia Ngee Low, Mahmoud A. Bassal, Yue Wu
Publikováno v:
Gastroenterology
Background & Aims Some oncogenes encode transcription factors, but few drugs have been successfully developed to block their activity specifically in cancer cells. The transcription factor SALL4 is aberrantly expressed in solid tumor and leukemia cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d870803882ebda006613d11fea7366ed
https://europepmc.org/articles/PMC7309153/
https://europepmc.org/articles/PMC7309153/
Autor:
Giridharan Periyasamy, Bee Hui Liu, Li Chai, Yue Wu, Kol Jia Yong, May Yin Lee, Siyu Wang, Glenn Kunath Bonney, Justin L. Tan, Yoganathan Kanagasundaram, Atsushi Suzuki, Yun Shen Chan, Zi Hui Tan, John M. Asara, Zhi Han Lim, Tan Boon Toh, Chan-Shuo Wu, Nikki R. Kong, Feng Li, Hon Man Chan, Yock Young Dan, Guo-Dong Lu, Edward Kai-Hua Chow, Alicia Stein, Wai Leong Tam, Huck-Hui Ng, Lissa Hooi, Guo Hao Ng, Siew Bee Ng, Joanna Z. Yeo, Chung Yan Leong, Daniel Geoffrey Tenen, Matan Thangavelu Thangavelu, Hong Kee Tan, Kia Ngee Low, Mahmoud A. Bassal, Siming Ma
Publikováno v:
Cancer Research. 80:1788-1788
Transcription factors are important drivers of cancer but the development of therapeutics against these factors has had limited success. We developed a stringent high-throughput chemical genetic screening platform to identify compounds that target on
Autor:
Henry Yang, Xiaoying Koh-Stenta, Joma Joy, Tim Chan, Alvin W. Hung, J. Sivaraman, Feng Li, Anders Poulsen, Yaw Sing Tan, Jeffrey Hill, Chandra S. Verma, Bee Hui Liu, Chan-Shuo Wu, Hong Kee Tan, C. S. Brian Chia, Chacko Jobichen, Jia Li, Jing Ping Tang, Li Chai, Daniel G. Tenen, Theodora X. Y. Chung
Publikováno v:
Proceedings of the National Academy of Sciences. 115
Sal-like 4 (SALL4) is a nuclear factor central to the maintenance of stem cell pluripotency and is a key component in hepatocellular carcinoma, a malignancy with no effective treatment. In cancer cells, SALL4 associates with nucleosome remodeling dea
Autor:
Li Chai, Xiaopan Yao, Ping Tang, Ailing Li, Donna Neuberg, Chong Gao, Gang Huang, Ha-Won Jeong, Youyang Yang, Daniel G. Tenen, Jiayun Lu, Bee Hui Liu
Publikováno v:
Journal of Clinical Investigation. 123:4195-4207
The embryonic self-renewal factor SALL4 has been implicated in the development of human acute myeloid leukemia (AML). Transgenic mice expressing the human SALL4B allele develop AML, which indicates that this molecule contributes to leukemia developme
Autor:
Bee Hui Liu, Jobichen, Chacko, Chia, C. S. Brian, Hon Man Chan, Tim, Jing Ping Tang, Chung, Theodora X. Y., Jia Li, Poulsen, Anders, Hung, Alvin W., Xiaoying Koh-Stenta, Yaw Sing Tan, Verma, Chandra S., Hong Kee Tan, Chan-Shuo Wu, Feng Li, Hill, Jeffrey, Joy, Joma, Yang, Henry, Li Chai, Sivaraman, J.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 7/24/2018, Vol. 115 Issue 30, pE7119-E7128, 10p
The polyclonal cytokine-induced killer (CIK) cells exhibit potent cytotoxicity against a variety of tumour cells including autologous and allogeneic acute myeloid leukaemic (AML) targets. At maturity, three lymphocyte subsets: CD3(-) CD56(+), CD3(+)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::867f42d8a85f9b68c0123dd224b4e63a
https://europepmc.org/articles/PMC2669823/
https://europepmc.org/articles/PMC2669823/
Publikováno v:
Oncogene. 27(29)
Most human cancers are characterized by genetic aberrations accompanied by altered expression and function of numerous genes. Applying genome-wide, microarray gene expression analysis to identify deregulated genes in different tumour types can provid
Autor:
Ha-Won Jeong, Li Chai, Jie He, Youyang Yang, Bee Hui Liu, Ailing Li, David Song, Wei Cui, Ye Guo, Jiayun Lu
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18372 (2011)
PLoS ONE
PLoS ONE
Our previous work shows that the stem cell factor SALL4 plays a central role in embryonic and leukemic stem cells. In this study, we report that SALL4 expression was higher in drug resistant primary acute myeloid leukemic patients than those from dru