Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Bee Hak Hong"'
Autor:
Seo-Young Park, Dong-Hyuk Choi, Jinsung Song, Uiseon Park, Hyeran Cho, Bee Hak Hong, Yaron R. Silberberg, Dong-Yup Lee
Designing and selecting cell culture media and their feeding are a key strategy to maximize culture performance in industrial biopharmaceutical processes. However, mammalian cells are very sensitive to their culture environment, requiring specific nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b877527e2ab06221e535a7fcb525161
https://doi.org/10.1101/2023.03.09.531884
https://doi.org/10.1101/2023.03.09.531884
Autor:
Seo-Young Park, Dong-Hyuk Choi, Jinsung Song, Uiseon Park, Hyeran Cho, Bee Hak Hong, Fumi Shozui, Yaron R. Silberberg, Dong-Yup Lee
Publikováno v:
IFAC-PapersOnLine. 55:31-36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa217012ff19c3541530f531b723b4f9
https://doi.org/10.1016/j.ifacol.2022.07.418
https://doi.org/10.1016/j.ifacol.2022.07.418
Autor:
Bee Hak Hong, Kwan Yong Choi, Hyung Jin Cha, Jehan Kim, Kyeong Sik Jin, Hee Cheon Lee, Hyeong Ju Lee, Moonhor Ree, Do Soo Jang, Eung-Sam Kim
Publikováno v:
Science of Advanced Materials. 6:2325-2333
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd93062cbf3eee92fb75881f4bcd6ce2
https://doi.org/10.1166/sam.2014.2202
https://doi.org/10.1166/sam.2014.2202
Autor:
Bee Hak Hong, Kwan Yong Choi, Hyung Jin Cha, Jae Sung Woo, Do Soo Jang, Yeon Gil Kim, Kyong-Tai Kim
Publikováno v:
Molecules and Cells. 36:39-46
Proteins have evolved to compensate for detrimental mutations. However, compensatory mechanisms for protein defects are not well understood. Using ketosteroid isomerase (KSI), we investigated how second-site mutations could recover defective mutant f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff3f4707cb706ef58935a94226ae214
https://doi.org/10.1007/s10059-013-0013-1
https://doi.org/10.1007/s10059-013-0013-1
Autor:
Bee Hak Hong, Kwan Yong Choi, Hyung Jin Cha, Jae-Hee Jeong, Eun Ju Shin, Young Sung Yun, Do Soo Jang
Publikováno v:
Biochimica et biophysica acta. 1864(10)
Ketosteroid isomerase (3-oxosteroid Δ(5)-Δ(4)-isomerase, KSI) from Pseudomonas putida catalyzes allylic rearrangement of the 5,6-double bond of Δ(5)-3-ketosteroid to 4,5-position by stereospecific intramolecular transfer of a proton. The active si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7f8dfe50ea6ceac037dcdbc3f65cf91
https://pubmed.ncbi.nlm.nih.gov/27375051
https://pubmed.ncbi.nlm.nih.gov/27375051
Autor:
Gyu Hyun Nam, Bee Hak Hong, Kwan Yong Choi, Sun Shin Cha, Young Sung Yun, Heung-Soo Lee, Yun Hee Oh
Publikováno v:
Biochemical Journal. 375:297-305
KSI (ketosteroid isomerase) from Comamonas testosteroni is a homodimeric enzyme that catalyses the allylic isomerization of Delta5-3-ketosteroids to their conjugated Delta4-isomers at a reaction rate equivalent to the diffusion-controlled limit. Base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f039e0b28b70195fa815c7102c2917
https://doi.org/10.1042/bj20030263
https://doi.org/10.1042/bj20030263
Contribution of a low-barrier hydrogen bond to catalysis is not significant in ketosteroid isomerase
Autor:
Bee Hak Hong, Kwan Yong Choi, Hyung Jin Cha, Sejeong Shin, Do Soo Jang, Gildon Choi, Hyeong Ju Lee, Hee Cheon Lee
Publikováno v:
Molecules and Cells
Low-barrier hydrogen bonds (LBHBs) have been proposed to have important influences on the enormous reaction rate increases achieved by many enzymes. Δ(5)-3-ketosteroid isomerase (KSI) catalyzes the allylic isomerization of Δ(5)-3-ketosteroid to its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6c697a4407069e4c44ce2dcb8cd54df
https://pubmed.ncbi.nlm.nih.gov/25947291
https://pubmed.ncbi.nlm.nih.gov/25947291
Publikováno v:
Biochemistry. 40:6828-6835
Δ5-3-ketosteroid isomerase (KSI) from Pseudomonas putida Biotype B catalyzes the allylic isomerization of Δ5-3-ketosteroids to their conjugated Δ4-isomers via a dienolate intermediate. Two electrophilic catalysts, Tyr-14 and Asp-99, are involved i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3269fd8e1d230b6055cb72edbb3264cc
https://doi.org/10.1021/bi002767+
https://doi.org/10.1021/bi002767+
Autor:
Sung Jong Lee, Bee Hak Hong, Joo-Hee Yoon, Kwan Yong Choi, Hyung Jin Cha, Chang Wook Park, Eung-Sam Kim
Publikováno v:
Journal of gynecologic oncology. 21(4)
Objective The aim of this study was to identify apoptosis-related genes of ovarian cancer cell lines following cisplatin treatment. Methods We used IC(50) values and fluorescence-activated cell sorting analysis to compare cell death in 2 ovarian canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf7fbbee0b3738250a326b27e3780ac8
https://pubmed.ncbi.nlm.nih.gov/21278888
https://pubmed.ncbi.nlm.nih.gov/21278888
Autor:
Soon Jin Oh, Bee Hak Hong, Kwan Yong Choi, Young Sung Yun, Do Soo Jang, Jimin Ju, Joon Won Park, Bong Jin Hong
Publikováno v:
Molecules and cells. 30(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c1ec1a9535a946ec2a8d5cb79c09314
https://pubmed.ncbi.nlm.nih.gov/21120630
https://pubmed.ncbi.nlm.nih.gov/21120630