Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Bedrich Mosinger"'
Autor:
Yan Li, Karen K. Yee, Robert F. Margolskee, Ken Iwatsuki, Bedrich Mosinger, Erwin Ilegems, Zaza Kokrashvili
Publikováno v:
British Journal of Nutrition. 111:S23-S29
In taste cells, taste receptors, their coupled G proteins and downstream signalling elements mediate the detection and transduction of sweet, bitter and umami compounds. In some intestinal endocrine cells, taste receptors and gustducin contribute to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70204866debbe2a1890fe5dc012b1c01
https://doi.org/10.1017/s0007114513002262
https://doi.org/10.1017/s0007114513002262
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 304:E651-E660
Sweet taste receptor subunits and α-gustducin found in enteroendocrine cells of the small intestine have been implicated in release of the incretin hormones glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) in re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cdc6ab08000ba64fe4e84579232dc2e
https://doi.org/10.1152/ajpendo.00471.2012
https://doi.org/10.1152/ajpendo.00471.2012
Publikováno v:
Journal of Medicinal Chemistry. 52:6931-6935
We show that phenoxy-auxin herbicides and lipid-lowering fibrates inhibit human but not rodent T1R3. T1R3 as a co-receptor in taste cells responds to sweet compounds and amino-acids; in endocrine cells of gut and pancreas T1R3 contributes to glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c64d98f81c4d7c8885ea617b34988bb
https://doi.org/10.1021/jm900823s
https://doi.org/10.1021/jm900823s
Publikováno v:
Annals of the New York Academy of Sciences. 1170:91-94
Glucagon-like peptide-1 (GLP-1) is an incretin hormone that underlies the augmented insulin release from the pancreas in response to glucose in the gut lumen more than to intravenous injected glucose (the "incretin effect"). GLP-1, found in enteroend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5096dfc0af2b7efa5d1d75430942297f
https://doi.org/10.1111/j.1749-6632.2009.04485.x
https://doi.org/10.1111/j.1749-6632.2009.04485.x
Autor:
Hongguang Shao, Bedrich Mosinger, Robert F. Margolskee, Stuart A. McCaughey, Michael G. Tordoff, Laura K. Alarcón, Alexander A. Bachmanov, Danielle R. Reed
Publikováno v:
Physiological Genomics. 34:338-348
Calcium and magnesium are essential for survival but it is unknown how animals detect and consume enough of these minerals to meet their needs. To investigate this, we exploited the PWK/PhJ (PWK) strain of mice, which, in contrast to the C57BL/6J (B6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3651a340249cd839b4272af074d38058
https://doi.org/10.1152/physiolgenomics.90200.2008
https://doi.org/10.1152/physiolgenomics.90200.2008
Autor:
Xiangru Xu, Magdalena Juhaszova, Michael J. Theodorakis, Byung Joon Kim, Zaza Kokrashvili, Robert F. Margolskee, Sic L. Chan, Michel Bernier, Bedrich Mosinger, Josephine M. Egan, Jie Zhou, Hyeon Ho Kim, Hyeung-Jin Jang, Olga D. Carlson
Publikováno v:
Proceedings of the National Academy of Sciences. 104:15069-15074
Glucagon-like peptide-1 (GLP-1), released from gut endocrine L cells in response to glucose, regulates appetite, insulin secretion, and gut motility. How glucose given orally, but not systemically, induces GLP-1 secretion is unknown. We show that hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3187311a3c9699d0d1d7d2aca6c3b60
https://doi.org/10.1073/pnas.0706890104
https://doi.org/10.1073/pnas.0706890104
Autor:
Erwin Ilegems, Zaza Kokrashvili, K. S. H. Salmon, Soraya P. Shirazi-Beechey, Robert F. Margolskee, Bedrich Mosinger, Jane Dyer, Emeline L. Maillet, Yuzo Ninomiya, Kristian Daly
Publikováno v:
Proceedings of the National Academy of Sciences. 104:15075-15080
Dietary sugars are transported from the intestinal lumen into absorptive enterocytes by the sodium-dependent glucose transporter isoform 1 (SGLT1). Regulation of this protein is important for the provision of glucose to the body and avoidance of inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cf1b13c601e896034b252e7de71ca8a
https://doi.org/10.1073/pnas.0706678104
https://doi.org/10.1073/pnas.0706678104
Autor:
Bedrich Mosinger, Yoshio Goshima, Paul A. Salin, Pappachan E. Kolattukudy, Naura Chounlamountri, Michèle Aguera, Véronique Rogemond, Claire Meissirel, Valérie Perrot, Emmanuelle Charrier, Marie-Françoise Belin, Nicole Thomasset, Jérôme Honnorat, Sophie Reibel
Publikováno v:
Genes to Cells
Genes to Cells, Wiley, 2006, 11 (12), pp.1337-1352. ⟨10.1111/j.1365-2443.2006.01024.x⟩
Genes to Cells, Wiley, 2006, 11 (12), pp.1337-1352. ⟨10.1111/j.1365-2443.2006.01024.x⟩
Collapsin response mediator proteins (CRMPs) consist of five homologous cytosolic proteins that participate in signal transduction involved in a variety of physiological events. CRMP1 is highly expressed during brain development; however, its functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db12d87a2c48d2ed2683f456939bb5f
https://doi.org/10.1111/j.1365-2443.2006.01024.x
https://doi.org/10.1111/j.1365-2443.2006.01024.x
Autor:
Bedrich Mosinger, Karen K. Yee, Yan Li, M. Rockwell Parker, Robert F. Margolskee, Katerina Dyomina, Kevin Redding, Valeriya Yevshayeva
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 110(30)
TAS1R taste receptors and their associated heterotrimeric G protein gustducin are involved in sugar and amino acid sensing in taste cells and in the gastrointestinal tract. They are also strongly expressed in testis and sperm, but their functions in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d646cc82e6cbd2c1a238c30b67e76593
https://pubmed.ncbi.nlm.nih.gov/23818598
https://pubmed.ncbi.nlm.nih.gov/23818598
Autor:
Heiner Westphal, Kathleen A. Mahon, Bedrich Mosinger, Stefano Bertuzzi, Alexander B. Zhadanov, Sing-Ping Huang, Hui Z. Sheng, Alexander Grinberg, Eric J. Lee, Tetsuya Fujii
Publikováno v:
Science. 272:1004-1007
During pituitary organogenesis, the progressive differentiation of distinct pituitary-specific cell lineages from a common primordium involves a series of developmental decisions and inductive interactions. Targeted gene disruption in mice showed tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e4cdbeee3383b6a77e7cf007c63cfaf
https://doi.org/10.1126/science.272.5264.1004
https://doi.org/10.1126/science.272.5264.1004