Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Bedri Karakas"'
Autor:
Syed S. Islam, Khawlah Qassem, Shafiqul Islam, Rashed R. Parag, Mohammed Z. Rahman, Walid A. Farhat, Herman Yeger, Abdelilah Aboussekhra, Bedri Karakas, Abu Shadat M. Noman
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-13 (2022)
Abstract Keap1 mutations regulate Nrf2 activity and lead to chemoresistance in cancers. Yet the underlying molecular mechanisms of chemoresistance are poorly explored. By focusing and genotyping head and neck squamous cell carcinoma (HNSCC) that had
Externí odkaz:
https://doaj.org/article/63807b26d5284eb1ba2fb9405a2b8a18
Publikováno v:
Cancers, Vol 15, Iss 20, p 5006 (2023)
Mutations in Keap1/Nrf2 in head and neck cancer result in abnormal cell growth. Progenitor cells, bulk tumor cells, and head and neck cancer stem cells (HN-CSCs) may all harbor these mutations. Nevertheless, whether Keap1/Nrf2 mutations in HN-CSCs ha
Externí odkaz:
https://doaj.org/article/5adf59c1115d491bb9e6db87e6c7f0ac
Autor:
Abu Shadat M. Noman, Rashed R. Parag, Muhammad I. Rashid, Mohammad Z. Rahman, Ali A. Chowdhury, Afrin Sultana, Chandsultana Jerin, Ayesha Siddiqua, Lutfur Rahman, Afsana Shirin, Junayed Nayeem, Reaz Mahmud, Sonam Akther, Rajib K. Shil, Ikram Hossain, Sharmin Alam, Arfina Chowdhury, Shabnam B. Basher, Abul Hasan, Shammy Bithy, Jannatul Aklima, Mizanur Rahman, Nabila Chowdhury, Tahmina Banu, Bedri Karakas, Herman Yeger, Walid A. Farhat, Syed S. Islam
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: Sonic hedgehog (Shh) and Nrf2 play a critical role in chemotherapeutic resistance. These two genes have been found to be dysregulated in head and neck squamous cell carcinomas (HNSCC). The purpose of this study was to analyze the expressi
Externí odkaz:
https://doaj.org/article/dec0b693ea5945a5b0e6cdec48d738a1
Publikováno v:
Frontiers in Oncology, Vol 9 (2020)
Background: Papillary thyroid cancer (PTC) is the most common type of thyroid malignancy. Serum thyroglobulin (Tg) levels are used to monitor PTC treatment response and recurrences however, in about 25% of the cases the sensitivity of this method is
Externí odkaz:
https://doaj.org/article/c31b91acc1ab41e08d3e0ee2122359a1
Autor:
Nisreen Al-Moghrabi, Maram Al-Showimi, Nujoud Al-Yousef, Bushra Al-Shahrani, Bedri Karakas, Lamyaa Alghofaili, Hannah Almubarak, Safia Madkhali, Hind Al Humaidan
Publikováno v:
Clinical Epigenetics, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background Constitutive methylation of tumor suppressor genes are associated with increased cancer risk. However, to date, the question of epimutational transmission of these genes remains unresolved. Here, we studied the potential transmiss
Externí odkaz:
https://doaj.org/article/a57d9ef0f1f549208a545219425bb2de
Autor:
Lamyaa Alghofaili, Hannah Almubarak, Khawlah Gassem, Syed S Islam, Serdar Coskun, Namik Kaya, Bedri Karakas
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223470 (2019)
Cell-free DNA (cfDNA) in the human blood circulation has been under investigation since its initial observation in 1948. Plasma cfDNA is known to be significantly elevated in diseased people. Due to possible variation in the population, evaluating cf
Externí odkaz:
https://doaj.org/article/6e08a0c547464094bf6f2d6f065dbe02
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126501 (2015)
The discovery of cell-free fetal DNA (cfDNA) circulating in the maternal blood has provided new opportunities for noninvasive prenatal diagnosis (NIPD). However, the extremely low levels of cfDNA within a high background of the maternal DNA in matern
Externí odkaz:
https://doaj.org/article/c486da72176b4041a346f8a3f6b0288a
Autor:
Ben Ho Park, Kurtis E. Bachman, Eike Gallmeier, Yuko Konishi, Joseph P. Garay, John P. Gustin, Josh Lauring, Abde M. Abukhdeir, Bedri Karakas, Hiroyuki Konishi
Supplementary Figure Legends 1-4 from Knock-in of Mutant K-ras in Nontumorigenic Human Epithelial Cells as a New Model for Studying K-ras–Mediated Transformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378b59285c9413cbc3fbbdcd3d809707
https://doi.org/10.1158/0008-5472.22367298.v1
https://doi.org/10.1158/0008-5472.22367298.v1
Autor:
Ben Ho Park, Kurtis E. Bachman, Eike Gallmeier, Yuko Konishi, Joseph P. Garay, John P. Gustin, Josh Lauring, Abde M. Abukhdeir, Bedri Karakas, Hiroyuki Konishi
Supplementary Table 1, Figures 1-4 from Knock-in of Mutant K-ras in Nontumorigenic Human Epithelial Cells as a New Model for Studying K-ras–Mediated Transformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fd267aacb2f56a355c86ef8c0d77fd7
https://doi.org/10.1158/0008-5472.22367295.v1
https://doi.org/10.1158/0008-5472.22367295.v1
Autor:
Ben Ho Park, Kurtis E. Bachman, Eike Gallmeier, Yuko Konishi, Joseph P. Garay, John P. Gustin, Josh Lauring, Abde M. Abukhdeir, Bedri Karakas, Hiroyuki Konishi
The oncogenic function of mutant ras in mammalian cells has been extensively investigated using multiple human and animal models. These systems include overexpression of exogenous mutant ras transgenes, conditionally expressed knock-in mouse models,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3a0660684f5aab2324d406106c5e665
https://doi.org/10.1158/0008-5472.c.6495501.v1
https://doi.org/10.1158/0008-5472.c.6495501.v1