Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Bedia Assy"'
Publikováno v:
The American Journal of Pathology. 168:170-175
Fas/FasL signaling is best known for induction of apoptosis. However, there is an alternate pathway of Fas signaling that induces inflammatory cytokines, particularly tumor necrosis factor (TNF)-alpha and interleukin (IL)-8. This pathway is prominent
Autor:
Raya Shalaginov, Amos Gilhar, Bedia Assy, Sima Serafimovich, Richard S. Kalish, Rachel Karry, Yehuda Ullmann
Publikováno v:
The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 59:B411-B415
The goal of this study was to determine the role of Fas-mediated apoptosis in human epidermal aging. Epidermal Fas expression and apoptosis are increased in aged human skin. Aging changes of human epidermis, including decreased epidermal thickness an
Autor:
Yehuda Ullmann, Bedia Assy, Richard S. Kalish, Amos Gilhar, Raya Shalaginov, R. Karry, Sima Serafimovich
Publikováno v:
British Journal of Dermatology. 150:56-63
Summary Background Aged human epidermis is characterized by morphological changes including flattening of the dermal–epidermal junction and a decrease in thickness. Objectives To determine the roles of proliferation, apoptosis, Fas (CD95), Fas liga
Autor:
Amos Gilhar, Richard S. Kalish, Yehuda Ullmann, Sima Serafimovich, Bedia Assy, Marina Landau, Raya Shalaginov
Publikováno v:
Clinical Immunology. 106:181-187
Alopecia areata is an autoimmune condition directed at hair follicles, which results in loss of hair. We have previously demonstrated that it is possible to transfer hair loss, along with the immunohistologic findings of alopecia areata, to human sca
Autor:
Raya Shalaginov, Amos Gilhar, Bedia Assy, Richard S. Kalish, Yehuda Ullmann, Hedviga Kerner, Sima Serafimovich
Publikováno v:
Journal of Investigative Dermatology. 119:384-391
This study was performed to ask whether psoriasis is a unique pathologic response of epidermis of psoriatic patients, or cells with natural killer receptors can induce psoriatic changes in skin from nonpsoriatic donors. Human nonlesional skin from fi
Autor:
Amos Gilhar, Bedia Assy, Marina Landau, Raya Shalaginov, Richard S. Kalish, Sima Serafimovich
Publikováno v:
Journal of Investigative Dermatology. 117:1357-1362
Alopecia areata is a tissue restricted autoimmune condition affecting the hair follicle, resulting in hair loss. The goal of this study was to test the hypothesis that the autoantigen of alopecia areata is melanocyte associated. Potential autoantigen
Autor:
Yehuda Ullmann, Bedia Assy, Amos Gilhar, Roberto d'Ovidio, Amos Etzioni, Anis Kaldawy, Ralf Paus, Gil Kaufman
Publikováno v:
Experimental Dermatology. 19:e347-e349
Please cite this paper as: An unexpected twist in alopecia areata pathogenesis: are NK cells protective and CD49b+ T cells pathogenic? Experimental Dermatology 2010; 19: e347–e349. Abstract: Natural killer (NK) cells have become a recent focus of i
Publikováno v:
Journal of Investigative Dermatology Symposium Proceedings. 4(3):207-210
Much evidence suggests that alopecia areata is a tissue restricted autoimmune disease. Alopecia areata responds to immunosuppressive agents, and is associated with other tissue restricted autoimmune diseases, including autoimmune thyroiditis and viti
Publikováno v:
Journal of Clinical Investigation. 101:62-67
Alopecia areata is a tissue-restricted autoimmune disease of the hair follicle, which results in hair loss and baldness. It is often psychologically devastating. The role of T lymphocytes in this disorder was investigated with cell transfer experimen
Autor:
Gil, Kaufman, Roberto, d'Ovidio, Anis, Kaldawy, Bedia, Assy, Yehuda, Ullmann, Amos, Etzioni, Ralf, Paus, Amos, Gilhar
Publikováno v:
Experimental dermatology. 19(8)
Natural killer (NK) cells have become a recent focus of interest in alopecia areata (AA) research. To further investigate their role in an established mouse model of AA, lesional skin from older C3H/HeJ mice with AA was grafted to young C3H/HeJ femal