Effect of sphingosine and phytosphingosine ceramide ratio on lipid arrangement and barrier function in skin lipid models.

Autor: Nădăban A; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Rousel J; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands; Centre for Human Drug Research, Leiden, The Netherlands., El Yachioui D; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Gooris GS; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Beddoes CM; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands., Dalgliesh RM; ISIS Neutron and Muon Source, Science and Technology Facilities Council, Rutherford Appleton Laboratory, Didcot, United Kingdom., Malfois M; ALBA Synchrotron, Barcelona, Spain., Rissmann R; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands; Centre for Human Drug Research, Leiden, The Netherlands; Leiden University Medical Center, Leiden, The Netherlands., Bouwstra JA; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Leiden, The Netherlands. Electronic address: bouwstra@lacdr.leidenuniv.nl.

Publikováno v: Journal of lipid research [J Lipid Res] 2023 Aug; Vol. 64 (8), pp. 100400. Date of Electronic Publication: 2023 Jun 08.

The importance of ceramide headgroup for lipid localisation in skin lipid models.

Autor: Beddoes CM; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, University of Leiden, Leiden, the Netherlands., Gooris GS; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, University of Leiden, Leiden, the Netherlands., Barlow DJ; Division of Pharmacy and Optometry, Manchester University, Manchester, United Kingdom., Lawrence MJ; Division of Pharmacy and Optometry, Manchester University, Manchester, United Kingdom., Dalgliesh RM; ISIS Neutron and Muon Source, Science and Technology Facilities Council, Rutherford Appleton Laboratory, Harwell Oxford, Didcot OX11 0QX, United Kingdom., Malfois M; ALBA Synchrotron, Carrer de la Llum 2-6, 08290 Cerdanyola del Valles, Barcelona, Spain., Demé B; Institut Laue-Langevin, Grenoble, France., Bouwstra JA; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, University of Leiden, Leiden, the Netherlands. Electronic address: bouwstra@chem.leidenuniv.nl.

Publikováno v: Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2022 Jun 01; Vol. 1864 (6), pp. 183886. Date of Electronic Publication: 2022 Feb 07.

The Importance of Free Fatty Chain Length on the Lipid Organization in the Long Periodicity Phase.

Autor: Beddoes CM; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, University of Leiden, 2311 EZ Leiden, The Netherlands., Rensen DE; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, University of Leiden, 2311 EZ Leiden, The Netherlands., Gooris GS; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, University of Leiden, 2311 EZ Leiden, The Netherlands., Malfois M; ALBA Synchrotron, Carrer de la Llum 2-26, 08290 Cerdanyola del Vallès, Barcelona, Spain., Bouwstra JA; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, University of Leiden, 2311 EZ Leiden, The Netherlands.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Apr 01; Vol. 22 (7). Date of Electronic Publication: 2021 Apr 01.

Arrangement of Ceramides in the Skin: Sphingosine Chains Localize at a Single Position in Stratum Corneum Lipid Matrix Models.

Autor: Beddoes CM; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, University of Leiden, Einsteinweg 55, Leiden 2333 CC, The Netherlands., Gooris GS; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, University of Leiden, Einsteinweg 55, Leiden 2333 CC, The Netherlands., Foglia F; Chemistry Department, Christopher Ingold Laboratories, University College London, London WC1H 0AJ, United Kingdom., Ahmadi D; Pharmaceutical Science Division, King's College London, London WC2R 2LS, United Kingdom., Barlow DJ; Pharmaceutical Science Division, King's College London, London WC2R 2LS, United Kingdom., Lawrence MJ; Division of Pharmacy and Optometry, Manchester University, Manchester M13 9PL, United Kingdom., Demé B; Institute Laue-Langevin, Grenoble 38000, France., Bouwstra JA; Division of BioTherapeutics, Leiden Academic Centre for Drug Research, University of Leiden, Einsteinweg 55, Leiden 2333 CC, The Netherlands.

Publikováno v: Langmuir : the ACS journal of surfaces and colloids [Langmuir] 2020 Sep 01; Vol. 36 (34), pp. 10270-10278. Date of Electronic Publication: 2020 Aug 20.

New insight into phase behavior and permeability of skin lipid models based on sphingosine and phytosphingosine ceramides.

Autor: Uche LE; Division BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Netherlands., Gooris GS; Division BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Netherlands., Beddoes CM; Division BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Netherlands., Bouwstra JA; Division BioTherapeutics, Leiden Academic Centre for Drug Research, Leiden University, Netherlands. Electronic address: bouwstra@chem.leidenuniv.nl.

Publikováno v: Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2019 Jul 01; Vol. 1861 (7), pp. 1317-1328. Date of Electronic Publication: 2019 Apr 13.