Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Becky Webb"'
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125272 (2015)
BackgroundThere is a significant clinical need for effective treatment of iron deficiency. A number of compounds that can be administered intravenously have been developed. This study examines how the compounds are handled by macrophages and their re
Externí odkaz:
https://doaj.org/article/03a5534c79544462bd123209e837c859
Autor:
A. B. Madhankumar, James R. Connor, Hali Jiang, Cheng Dong, Xiaojun Lian, Joshua Reynolds, Jian Yang, Lauren N. Randolph, Gloria B. Kim, Virginia Aragon-Sanabria, Becky Webb
Publikováno v:
Bioactive Materials, Vol 5, Iss 3, Pp 624-635 (2020)
Bioactive Materials
Bioactive Materials
Glioblastoma (GBM), the deadliest form of brain cancer, presents long-standing problems due to its localization. Chimeric antigen receptor (CAR) T cell immunotherapy has emerged as a powerful strategy to treat cancer. IL-13-receptor-α2 (IL13Rα2), p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39ef9157524176498a4e3d55af7f310b
http://www.sciencedirect.com/science/article/pii/S2452199X20300712
http://www.sciencedirect.com/science/article/pii/S2452199X20300712
Autor:
Justin D. Lathia, Katie M. Troike, James R. Connor, Amanda M. Snyder, Becky Webb, Madison K. Kuhn, Chachrit Khunsriraksakul, Hong Gang Wang, Elizabeth A. Proctor, Ganesh Shenoy
Publikováno v:
Neuro Oncol
Glioblastoma (GBM) remains one of the most difficult to treat malignancies facing modern medicine. The strong migratory and invasive capacity of GBM cells allows for diffuse invasion into neighboring healthy brain which presents a significant hurdle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::695560c7a2213bd5b21d1a2ee33e8a0f
https://europepmc.org/articles/PMC8598759/
https://europepmc.org/articles/PMC8598759/
Autor:
Joshua B. Rubin, Michael E. Berens, Jill S. Barnholtz-Sloan, Brad E. Zacharia, Becky Webb, Bhavyata Pandya, Justin D. Lathia
Publikováno v:
Neuro-Oncology. 23:vi209-vi209
Sexual dimorphism in incidence and the clinical outcomes of Glioblastoma (GBM) has been reported, however, our knowledge of contributing biological mechanisms is limited. Iron acquisition is key to robust tumor growth. Upregulation of Transferrin (TF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::650c53f81e562de404ea8eb7e99929c2
https://doi.org/10.1093/neuonc/noab196.837
https://doi.org/10.1093/neuonc/noab196.837
Autor:
Becky Webb, Oliver D. Mrowczynski, Vagisha Ravi, Xiaoli Liu, A. B. Madhankumar, James R. Connor
Liposomes are lipid bilayer nanovesicles that have inherent ability to deliver therapeutic and imaging agents to the tumor cells due to enhanced permeability and retention effect (EPR effect) and also by active targeting mechanism. The major hurdles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d7ad0af5a2c29db193e1bb5d0b8a05
https://europepmc.org/articles/PMC5693103/
https://europepmc.org/articles/PMC5693103/
Autor:
Becky Webb, Cody Weston, Anne M. Nixon, James D. Connor, Elizabeth B. Neely, Ahmed Alkhateeb, William Hund
Publikováno v:
Journal of Cancer Science & Therapy.
Background: We investigated the effects of the frequently polymorphic high iron gene (HFE), on tumor growth in a novel mouse model. We hypothesized that host mutations in the HFE protein modify tumor progression. Methods: C57BL/6 mice possessing eith
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e524fae8e75eab2c6cfba8f9c6e62b60
https://doi.org/10.4172/1948-5956.1000353
https://doi.org/10.4172/1948-5956.1000353
Autor:
Michael Glantz, Oliver D. Mrowczynski, A. B. Madhankumar, Brad E. Zacharia, Li Chong Xu, James R. Connor, Christopher A. Siedlecki, Akiva Mintz, Becky Webb
Publikováno v:
Cancer Research. 77:745-745
High grade brain tumors like glioblastoma multiforme (GBM) and certain other brain metastatic cancers possess high tumor invasive and infiltrating properties making them harder to detect. Identification of cancer stem cells and exosomes secreted by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8253e9954ea1c597e84eaa0bd9675b04
https://doi.org/10.1158/1538-7445.am2017-745
https://doi.org/10.1158/1538-7445.am2017-745
Autor:
Yan Cheng, Joshua E. Allen, Wafik S. El-Deiry, Becky Webb, Siu Yuan Huang, James R. Connor, Yunsheng Yuan, Weiwei Yang, Li Zhang, Yi Zhang, Chang Gong Liu, Xiuping Liu, Zhimin Lu, Xingcong Ren, Jin Ming Yang, Arthur Berg
Publikováno v:
Cancer biologytherapy. 15(5)
The malignant phenotype of glioblastoma multiforme (GBM) is believed to be largely driven by glioma stem-like cells (GSCs), and targeting GSCs is now considered a promising new approach to treatment of this devastating disease. Here, we show that SN5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730c6a79c939e2abf252d5ee2bccc816
https://pubmed.ncbi.nlm.nih.gov/24557012
https://pubmed.ncbi.nlm.nih.gov/24557012
Autor:
Xiaoli Liu, Qing X. Yang, Becky Webb, James D. Connor, A.B. Madhankumar, Patti A. Miller, Akiva Mintz
Publikováno v:
Neuro-Oncology. 18:vi50-vi50
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aba0b9ae7ac44dea4e9090778f11310
https://doi.org/10.1093/neuonc/now212.205
https://doi.org/10.1093/neuonc/now212.205
Publikováno v:
Cancer Research. 73:4436-4436
Increased iron requirements and heightened iron metabolism is among the key characteristics of highly proliferative cancer cells. As the major iron storage protein, ferritin expression is elevated in cancer cells and we have previously shown that fer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbfa1e3b9f7480145c2b758c8f4b96fa
https://doi.org/10.1158/1538-7445.am2013-4436
https://doi.org/10.1158/1538-7445.am2013-4436