Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Becky Slagle"'
Autor:
Ganesh Shenoy, Becky Slagle-Webb, Chachrit Khunsriraksakul, Bhavyata Pandya Shesh, Jingqin Luo, Vladimir Khristov, Nataliya Smith, Alireza Mansouri, Brad E. Zacharia, Sheldon Holder, Justin D. Lathia, Jill S. Barnholtz-Sloan, James R. Connor
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The association between anemia and outcomes in glioblastoma patients is unclear. We analyzed data from 1346 histologically confirmed adult glioblastoma patients in the TriNetX Research Network. Median hemoglobin and hematocrit levels were qu
Externí odkaz:
https://doaj.org/article/a9d3c20eb2d84732ac22809af3797fa9
Autor:
Vagisha Ravi, Achuthamangalam B Madhankumar, Thomas Abraham, Becky Slagle-Webb, James R Connor
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221952 (2019)
Elevated expression of the iron regulatory protein, ferritin heavy chain 1 (FTH1), is increasingly being associated with high tumor grade and poor survival outcomes in glioblastoma. Glioma initiating cells (GICs), a small population of stem-like cell
Externí odkaz:
https://doaj.org/article/8ed939399d5e488e889c35212c2d1f6e
Autor:
A B Madhankumar, Oliver D Mrowczynski, Becky Slagle-Webb, Vagisha Ravi, Alexandre J Bourcier, Russell Payne, Kimberly S Harbaugh, Elias Rizk, James R Connor
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0181529 (2018)
Peripheral nerve sheath tumors are benign tumors that have the potential to transform into malignant peripheral nerve sheath tumors (MPNSTs). Interleukin-13 receptor alpha 2 (IL13Rα2) is a cancer associated receptor expressed in glioblastoma and oth
Externí odkaz:
https://doaj.org/article/3d581631ae1648e8b5e675d0ea7384cd
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 4, Iss 5, Pp 388-399 (2002)
We have found that binding sites for interleukin-13. ( IL13) are overexpressed in a vast majority of high-grade astrocytomas. (HGAs). These binding sites for IL-13 are distinct from the physiological receptor in that it does not bind IL-4. We also de
Externí odkaz:
https://doaj.org/article/94a443570ceb4fc78c8a059b46df8a2d
Autor:
Sang Y Lee, Becky Slagle-Webb, Elias Rizk, Akshal Patel, Patti A Miller, Shen-Shu Sung, James R Connor
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108166 (2014)
The standard chemotherapy for brain tumors is temozolomide (TMZ), however, as many as 50% of brain tumors are reportedly TMZ resistant leaving patients without a chemotherapeutic option. We performed serial screening of TMZ resistant astrocytoma cell
Externí odkaz:
https://doaj.org/article/12064bc9895e41299dd79001321b6785
Autor:
Bhavyata Shesh, Becky Slagle-Webb, Ganesh Shenoy, Vladimir Khristov, Brad E. Zacharia, James R. Connor
Publikováno v:
Journal of Cancer Research and Clinical Oncology.
Autor:
Ganesh Shenoy, Sina Kheirabadi, Zaman Ataie, Kondaiah Palsa, Quinn Wade, Chachrit Khunsriraksakul, Vladimir Khristov, Becky Slagle-Webb, Justin D. Lathia, Hong-Gang Wang, Amir Sheikhi, James R. Connor
Glioblastoma is one of the deadliest malignancies facing modern oncology today. The ability of glioblastoma cells to diffusely spread into neighboring healthy brain makes complete surgical resection nearly impossible and contributes to the recurrent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7deb3484a286d9a6da3a0aba3cfd4182
https://doi.org/10.1101/2022.10.13.512175
https://doi.org/10.1101/2022.10.13.512175
Publikováno v:
Anticancer Research. 41:2795-2804
Background/aim Neuroblastoma is the most common childhood extracranial solid malignancy. Although cancer cells need iron and lipids for active cell division, possible links between iron and lipid metabolism in neuroblastomas have not been studied. Ma
Publikováno v:
Anticancer Research. 41:1171-1181
Background/aim We have previously reported the identification of the cytotoxic chemotype compound-I (CC-I) from a chemical library screening against glioblastoma. Materials and methods The biological activity of CC-I on drug-resistant neuroblastomas
Autor:
Ganesh Shenoy, Kondaiah Palsa, Quinn Wade, Chachrit Khunsriraksakul, Vladimir Khristov, Becky Slagle-Webb, Justin Lathia, Hong-Gang Wang, James Connor
Publikováno v:
Neuro-Oncology. 24:vii278-vii279
Glioblastoma represents one of the most difficult-to-treat malignancies as evidenced by the poor prognosis associated with a diagnosis. The ability of glioblastoma cells to diffusely infiltrate into healthy brain tissue renders complete surgical rese