Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Becky Rivoire"'
Autor:
Patrick J. Brennan, Varalakshmi D. Vissa, Hansuk Kim, Sang Nae Cho, Nathan A. Groathouse, Becky Rivoire, Hyeyoung Lee
Publikováno v:
Journal of Clinical Microbiology. 42:1666-1672
The need for molecular tools for the differentiation of isolates of Mycobacterium leprae , the organism that causes leprosy, is urgent in view of the continuing high levels of new case detection, despite years of aggressive chemotherapy and the conse
Autor:
Chaman Ranjit, Bishwa Raj Sapkota, Chhatra B. Kunwar, Patrick J. Brennan, Becky Rivoire, Eric Zhou, Robin Mason, Mark Wolff, Nathan A. Groathouse, RA Hawksworth, Christine Sizemore, Stephen TerLouw, Melinda Tibbals, Saraswoti Khadge, Mamodikoe Makhene, Min B Thapa, Dewei She, Murdo Macdonald, Tina Dube, Carol Smith, Kapil D. Neupane, Deanna A. Hagge
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 5, p e2811 (2014)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background New tools are required for the diagnosis of pre-symptomatic leprosy towards further reduction of disease burden and its associated reactions. To address this need, two new skin test antigens were developed to assess safety and efficacy in
Autor:
Stewart T. Cole, Patrick J. Brennan, J. Mccormick, Becky Rivoire, Maria Cristina Vidal Pessolani, S. A. Hefta, D. R. Smith
Publikováno v:
The Journal of Experimental Medicine
The study of tissue-derived Mycobacterium leprae provides insights to the immunopathology of leprosy and helps identify broad molecular features necessary for mycobacterial parasitism. A major membrane protein (MMP-II) of in vivo-derived M. leprae pr
Autor:
Becky Rivoire, Vijay Mehra, S W Hunter, Patrick J. Brennan, C M Bozic, Maria Cristina Vidal Pessolani, S. A. Hefta
Publikováno v:
Infection and Immunity. 62:2417-2425
The decline in prevalence of leprosy is not necessarily matched by a fall in incidence, emphasizing the need for new antigens to measure disease transmission and reservoirs of infection. Mycobacterium leprae obtained from armadillo tissues was disrup
Autor:
Howard R. Morris, Becky Rivoire, Michael R. McNeil, Kay-Hooi Khoo, Anne Dell, Gurdyal S. Besra, Patrick J. Brennan
Publikováno v:
Biochemistry. 32:347-355
The highly antigenic surface glycolipids of serovars of the Mycobacterium avium complex are glycopeptidolipids of the general structure [formula: see text] However, it has recently been shown [Riviere, M., & Puzo, G. (1991) J. Biol. Chem. 266, 9057-9
Autor:
David W. Gammon, Patrick J. Brennan, Becky Rivoire, Gerald O. Aspinall, Delphi Chatterjee, Ramesh K. Sood
Publikováno v:
Carbohydrate Research. 237:57-77
The pentasaccharide hapten released from the glycopeptidolipid (GPL) antigen of M. avium serovar 26 has been characterized as O-(2,4-di-O-methyl-alpha-L-fucopyranosyl)-(1-->4)- O-beta-D-glucopyranosyluronic acid-(1-->4)-O-(2-O-methyl-alpha-L-fucopyra
Publikováno v:
Journal of Biological Chemistry. 267:6234-6239
Previously we had demonstrated that the termini of the arabinan component of mycobacterial cell wall arabinogalactan, the site of mycolic acid location, consists mostly of clusters of a pentaarabinofuranoside, [beta-D-Araf-(1----2)-alpha-D-Araf-(1---
Autor:
Nathan A. Groathouse, Patrick J. Brennan, Becky Rivoire, Miyako Kimura, Sang Nae Cho, David Gingrich, Rama Murthy Sakamuri, Varalakshmi Vissa, Susan Krueger-Koplin
Publikováno v:
Journal of clinical microbiology. 47(6)
Mycobacterium leprae is the noncultivable pathogen of leprosy. Since the genome sequence of an isolate of M. leprae has become available, multiple-locus variable-number tandem-repeat (VNTR) analysis (MLVA) has been explored as a tool for strain typin
Publikováno v:
Journal of Biological Chemistry. 265:14065-14068
This study addresses a major obstacle to vaccine development for leprosy, the isolation and characterization of the native protein antigens of the leprosy bacillus. Mycobacterium leprae harvested from armadillos was subjected to a simple fractionatio
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 8, Iss 5, p e2791 (2014)
PLoS Neglected Tropical Diseases, Vol 8, Iss 5, p e2791 (2014)
True incidence of leprosy and its impact on transmission will not be understood until a tool is available to measure pre-symptomatic infection. Diagnosis of leprosy disease is currently based on clinical symptoms, which on average take 3–10 years t