Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Becky L Conway-Campbell"'
Autor:
Benjamin P Flynn, Matthew T Birnie, Yvonne M Kershaw, Audrys G Pauza, Sohyoung Kim, Songjoon Baek, Mark F Rogers, Alex R Paterson, Diana A Stavreva, David Murphy, Gordon L Hager, Stafford L Lightman, Becky L Conway-Campbell
Publikováno v:
PLoS Genetics, Vol 17, Iss 8, p e1009737 (2021)
Ultradian glucocorticoid rhythms are highly conserved across mammalian species, however, their functional significance is not yet fully understood. Here we demonstrate that pulsatile corticosterone replacement in adrenalectomised rats induces a dynam
Externí odkaz:
https://doaj.org/article/ebb7253002144d5885d6bce3701f46a0
Autor:
Mitsuhiro Yoshimura, Benjamin P. Flynn, Yvonne M. Kershaw, Zidong Zhao, Yoichi Ueta, Stafford L. Lightman, Becky L. Conway-Campbell
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Here we demonstrate, in rodents, how the timing of feeding behaviour becomes disordered when circulating glucocorticoid rhythms are dissociated from lighting cues; a phenomenon most commonly associated with shift-work and transmeridian trave
Externí odkaz:
https://doaj.org/article/bcadd1670f5c46de9d4df0ba63659c00
Autor:
Matthew T. Birnie, Matthew D. B. Claydon, Oliver Troy, Benjamin P. Flynn, Mitsuhiro Yoshimura, Yvonne M. Kershaw, Zidong Zhao, Rebecca C. R. Demski-Allen, Gareth R. I. Barker, E. Clea Warburton, Zuner A. Bortolotto, Stafford L. Lightman, Becky L. Conway-Campbell
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Disrupted circadian activity is associated with many neuropsychiatric disorders. A major coordinator of circadian biological systems is adrenal glucocorticoid secretion which exhibits a pronounced preawakening peak that regulates metabolic, immune, a
Autor:
Matthew T. Birnie, Alen V. Eapen, Yvonne M. Kershaw, David Lodge, Graham L. Collingridge, Becky L. Conway‐Campbell, Stafford L. Lightman
Publikováno v:
Journal of neuroendocrinologyREFERENCES. 34(10)
Over 50% of depressed patients show hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis. Conventional therapy takes weeks to months to improve symptoms. Ketamine has rapid onset antidepressant effects. Yet its action on HPA axis activity i
Autor:
Matthew T. Birnie, Matthew D.B. Claydon, Benjamin P. Flynn, Mitsuhiro Yoshimura, Yvonne M. Kershaw, Rebecca C.R. Demski-Allen, Gareth R.I. Barker, E. Clea Warburton, Zuner A. Bortolotto, Stafford L. Lightman, Becky L. Conway-Campbell
Neuropsychiatric disorders such as major depression and schizophrenia are highly prevalent and contribute substantially to disease burden worldwide. Despite this, progress understanding the pathophysiology has remained largely elusive, yet these diso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d6aba9fffa08156304733ee8ebb3d98
https://doi.org/10.1101/2022.07.12.499774
https://doi.org/10.1101/2022.07.12.499774
Autor:
Jee-Hyun Yi, Chinedu Udeh-Momoh, Stafford L. Lightman, Eleanor Waite, Becky L. Conway-Campbell, Daniel J. Whitcomb, Thomas M. Piers, Garry Whitehead, Kwangwook Cho
Experience-dependent synaptic plasticity is important for learning and memory and regulated by the functions of N-methyl-D-aspartate (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptors. Glucocorticoids have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78e2acd10599a559494c86d03ac38521
https://doi.org/10.21203/rs.3.rs-923210/v1
https://doi.org/10.21203/rs.3.rs-923210/v1
Autor:
Matthew T. Birnie, Alex Paterson, Diana A. Stavreva, YM Kershaw, Becky L. Conway-Campbell, Audrys G Pauza, Songjoon Baek, David Murphy, Mark F. Rogers, Benjamin P. Flynn, Sohyoung Kim, Gordon L. Hager, Stafford L. Lightman
Publikováno v:
PLoS Genetics, Vol 17, Iss 8, p e1009737 (2021)
Flynn, B P, Birnie, M T, Kershaw, Y M, Pauza, A G, Kim, S, Baek, S, Rogers, M F, Paterson, A R, Stavreva, D A, Murphy, D, Hager, G L, Lightman, S L & Conway-Campbell, B L 2021, ' Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver ', PLoS Genetics, vol. 17, no. 8, e1009737, pp. e1009737 . https://doi.org/10.1371/journal.pgen.1009737
PLoS Genetics
Flynn, B P, Birnie, M T, Kershaw, Y M, Pauza, A G, Kim, S, Baek, S, Rogers, M F, Paterson, A R, Stavreva, D A, Murphy, D, Hager, G L, Lightman, S L & Conway-Campbell, B L 2021, ' Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver ', PLoS Genetics, vol. 17, no. 8, e1009737, pp. e1009737 . https://doi.org/10.1371/journal.pgen.1009737
PLoS Genetics
Ultradian glucocorticoid rhythms are highly conserved across mammalian species, however, their functional significance is not yet fully understood. Here we demonstrate that pulsatile corticosterone replacement in adrenalectomised rats induces a dynam
Publikováno v:
Current Opinion in Endocrine and Metabolic Research. 25:100363
Autor:
Naofumi Ikeda, Tetsu Miyamoto, Kazuaki Nishimura, Takashi Maruyama, Kazuhiko Baba, Yuki Nonaka, Masaharu Kataoka, Stafford L. Lightman, Mitsuhiro Yoshimura, Yoichi Ueta, Haruki Nishimura, Masatomo Mori, Kenya Sanada, Becky L. Conway-Campbell
Publikováno v:
Sanada, K, Yoshimura, M, Ikeda, N, Baba, K, Nishimura, H, Nishimura, K, Nonaka, Y, Maruyama, T, Miyamoto, T, Mori, M, Conway-Campbell, B, Lightman, S, Kataoka, M & Ueta, Y 2021, ' Chemogenetic activation of endogenous arginine vasopressin exerts anorexigenic effects via central nesfatin-1/NucB2 pathway ', The journal of physiological sciences : JPS, vol. 71, no. 1, 18, pp. 18 . https://doi.org/10.1186/s12576-021-00802-4
We examined whether the chemogenetic activation of endogenous arginine vasopressin (AVP) affects central nesfatin-1/NucB2 neurons, using a transgenic rat line that was previously generated. Saline (1 mL/kg) or clozapine-N-oxide (CNO, 1 mg/mL/kg), an
Autor:
John R. Pooley, Mark F. Rogers, Stafford L. Lightman, Becky L. Conway-Campbell, Felicity E. Stubbs, Caroline A Rivers
Publikováno v:
Rivers, C A, Rogers, M F, Stubbs, F E, Conway-Campbell, B L, Lightman, S L & Pooley, J R 2019, ' Glucocorticoid Receptor-Tethered Mineralocorticoid Receptors Increase Glucocorticoid-Induced Transcriptional Responses ', Endocrinology, vol. 160, no. 5, pp. 1044-1056 . https://doi.org/10.1210/en.2018-00819
Endocrinology
Endocrinology
Mineralocorticoid and glucocorticoid receptors (MRs and GRs) constitute a functionally important dual receptor system detecting and transmitting circulating corticosteroid signals. High expression of MRs and GRs occurs in the same cells in the limbic