Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Becky Bola"'
Autor:
Nadine S. Jahchan, Jing Shan Lim, Becky Bola, Karen Morris, Garrett Seitz, Kim Q. Tran, Lei Xu, Francesca Trapani, Christopher J. Morrow, Sandra Cristea, Garry L. Coles, Dian Yang, Dedeepya Vaka, Michael S. Kareta, Julie George, Pawel K. Mazur, Thuyen Nguyen, Wade C. Anderson, Scott J. Dylla, Fiona Blackhall, Martin Peifer, Caroline Dive, Julien Sage
Publikováno v:
Cell Reports, Vol 16, Iss 3, Pp 644-656 (2016)
Small cell lung cancer (SCLC) is a neuroendocrine lung cancer characterized by fast growth, early dissemination, and rapid resistance to chemotherapy. We identified a population of long-term tumor-propagating cells (TPCs) in a mouse model of SCLC. Th
Externí odkaz:
https://doaj.org/article/42469f1e4e5a450c8d76fbf3b09b570b
Autor:
Laura Feeney, Samuel Rack, Hitesh Mistry, Becky Bola, Andrew McPartlin, Andrew Sykes, Robert Metcalf
Publikováno v:
Journal of Clinical Oncology. 40:e18016-e18016
e18016 Background: Immune checkpoint blockade of the programmed death-1 receptor (PD1) with nivolumab improves survival for patients with platinum resistant recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC). However, response rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9048c6417b62f7534b286eed37a4711
https://doi.org/10.1200/jco.2022.40.16_suppl.e18016
https://doi.org/10.1200/jco.2022.40.16_suppl.e18016
Autor:
Khaireah Mubarak, Robert Metcalf, Guy N J Betts, Samuel Rack, David H. J. Morgan, Becky Bola, Kevin J. Harrington, Andrew J Wallace, Tracy Hussell
Publikováno v:
Journal of Clinical Oncology. 38:6585-6585
6585 Background: TP53 mutations are reported in 5% of patients with adenoid cystic carcinoma (ACC). Whilst TP53 mutations are associated with adverse clinical outcomes across multiple tumour types, their prognostic significance in ACC is unknown. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37197a65701e619151e273781ed10462
https://doi.org/10.1200/jco.2020.38.15_suppl.6585
https://doi.org/10.1200/jco.2020.38.15_suppl.6585
Autor:
Julie George, Dian Yang, Wade C. Anderson, Becky Bola, Michael S. Kareta, Garry L. Coles, Thuyen Nguyen, Fiona H Blackhall, Julien Sage, Francesca Trapani, Garrett Seitz, Pawel K. Mazur, Jing Shan Lim, Martin Peifer, Lei Xu, Christopher J. Morrow, Sandra Cristea, Dedeepya Vaka, Caroline Dive, Nadine Jahchan, Kim Q.t. Tran, Karen Morris, Scott J. Dylla
Publikováno v:
Jahchan, N S, Lim, J S, Bola, B, Morris, K, Seitz, G, Tran, K Q, Xu, L, Trapani, F, Morrow, C, Cristea, S, Coles, G L, Yang, D, Vaka, D, Kareta, M S, George, J, Mazur, P K, Nguyen, T, Anderson, W C, Dylla, S J, Blackhall, F, Peifer, M, Dive, C & Sage, J 2016, ' Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer ', Cell Reports, vol. 16, no. 3, pp. 644-56 . https://doi.org/10.1016/j.celrep.2016.06.021
Cell Reports, Vol 16, Iss 3, Pp 644-656 (2016)
Cell Reports, Vol 16, Iss 3, Pp 644-656 (2016)
SummarySmall cell lung cancer (SCLC) is a neuroendocrine lung cancer characterized by fast growth, early dissemination, and rapid resistance to chemotherapy. We identified a population of long-term tumor-propagating cells (TPCs) in a mouse model of S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11eaca2bbe8ca8036d32b79fab14fefc
https://doi.org/10.1016/j.celrep.2016.06.021
https://doi.org/10.1016/j.celrep.2016.06.021
Autor:
Peter T. Ruane, Laura F. Gumy, Becky Bola, Beverley Anderson, Marcin J. Wozniak, Casper C. Hoogenraad, Victoria J. Allan
Publikováno v:
Ruane, P, Gumy, L F, Bola, B, Anderson, B, Wozniak, M, Hoogenraad, C C & Allan, V 2016, ' Tumour Suppressor Adenomatous Polyposis Coli (APC) localisation is regulated by both Kinesin-1 and Kinesin-2 ', Scientific Reports, vol. 6, 27456 . https://doi.org/10.1038/srep27456
Scientific Reports
Scientific Reports
Microtubules and their associated proteins (MAPs) underpin the polarity of specialised cells. Adenomatous polyposis coli (APC) is one such MAP with a multifunctional agenda that requires precise intracellular localisations. Although APC has been foun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::79992db5fca4d766ce0febe3a664b2fb
https://dspace.library.uu.nl/handle/1874/343656
https://dspace.library.uu.nl/handle/1874/343656
Autor:
Becky Bola, Viki Allan
Publikováno v:
Biochemical Society Transactions. 37:961-965
The ER (endoplasmic reticulum) is a fascinating organelle that is highly dynamic, undergoing constant movement and reorganization. It has many key roles, including protein synthesis, folding and trafficking, calcium homoeostasis and lipid synthesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f59542a5277c7b5e11a4a38778685c
https://doi.org/10.1042/bst0370961
https://doi.org/10.1042/bst0370961
Autor:
Becky Bola, Kim Brownhill, Yen Ching Yang, Marcin J. Woźniak, Vesselina Levakova, Victoria J. Allan
Publikováno v:
Journal of Cell Science. 122:1979-1989
Generating the extended endoplasmic reticulum (ER) network depends on microtubules, which act as tracks for motor-driven ER tubule movement, generate the force to extend ER tubules by means of attachment to growing microtubule plus-ends and provide s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddbffbed2c2402d4f70785317c6d49e3
https://doi.org/10.1242/jcs.041962
https://doi.org/10.1242/jcs.041962
Autor:
Brian A. Telfer, Kaye J. Williams, Kathryn G. Blount, Susan E. Critchlow, Ian J. Stratford, Amy L. Chadwick, Paul D. Smith, Becky Bola, Filippos Michopoulos
Publikováno v:
Molecular cancer therapeutics. 13(12)
Inhibition of the monocarboxylate transporter MCT1 by AZD3965 results in an increase in glycolysis in human tumor cell lines and xenografts. This is indicated by changes in the levels of specific glycolytic metabolites and in changes in glycolytic en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62e2c32b4432fcd95f7ec66d40e41078
https://pubmed.ncbi.nlm.nih.gov/25281618
https://pubmed.ncbi.nlm.nih.gov/25281618
Autor:
Stuart D Pepper, Cassandra L Hodgkinson, Deborah J. Burt, Daisuke Nonaka, Fiona H Blackhall, Paul P. Kelly, Francesca Trapani, Mahmood Ayub, Crispin J. Miller, Lynsey Priest, Robert Metcalf, Radoslaw Polanski, Alastair Greystoke, Matthew G Krebs, Karen Morris, Caroline Dive, Jenny Antonello, Suzanne Faulkner, Christopher J. Morrow, Becky Bola, Ged Brady, Yaoyong Li, Louise Carter, Dominic G. Rothwell, Catriona Tate, Kathryn Simpson
Publikováno v:
Nature medicine. 20(8)
Small-cell lung cancer (SCLC), an aggressive neuroendocrine tumor with early dissemination and dismal prognosis, accounts for 15-20% of lung cancer cases and ∼200,000 deaths each year. Most cases are inoperable, and biopsies to investigate SCLC bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da3b65a1eaed9424e8dbf7fc0a48bfa
https://pubmed.ncbi.nlm.nih.gov/24880617
https://pubmed.ncbi.nlm.nih.gov/24880617
Autor:
Stuart D Pepper, Matthew G Krebs, Deborah J. Burt, Y. Li, Suzanne Faulkner, J. Tugwood, Cassandra L Hodgkinson, Christopher J. Morrow, F. Blackhall, Daisuke Nonaka, Francesca Trapani, Crispin J. Miller, Dominic G. Rothwell, Alastair Greystoke, Becky Bola, Lynsey Priest, Louise Carter, Robert Metcalf, Catriona Tate, Gerard Brady, Kathryn Simpson, Radoslaw Polanski, Paul P. Kelly, Caroline Dive, Mahmood Ayub, Karen Morris, Jenny Antonello
Publikováno v:
Lung Cancer. 87:S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88446bb50eae0c18f6a8108afa4732e2
https://doi.org/10.1016/s0169-5002(15)50001-9
https://doi.org/10.1016/s0169-5002(15)50001-9