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Akademický článek

Altering the Binding Properties of PRDM9 Partially Restores Fertility across the Species Boundary.

Autor: Davies B; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Gupta Hinch A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Cebrian-Serrano A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Alghadban S; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Becker PW; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Biggs D; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Hernandez-Pliego P; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Preece C; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Moralli D; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Zhang G; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Myers S; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Department of Statistics, University of Oxford, Oxford, United Kingdom., Donnelly P; Wellcome Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.; Department of Statistics, University of Oxford, Oxford, United Kingdom.

Publikováno v: Molecular biology and evolution [Mol Biol Evol] 2021 Dec 09; Vol. 38 (12), pp. 5555-5562.

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Akademický článek

Adaptor Template Oligo-Mediated Sequencing (ATOM-Seq) is a new ultra-sensitive UMI-based NGS library preparation technology for use with cfDNA and cfRNA.

Autor: Dunwell TL; GeneFirst Ltd, Building E5, Culham Science Centre, Abingdon, OX14 3DB, UK., Dailey SC; GeneFirst Ltd, Building E5, Culham Science Centre, Abingdon, OX14 3DB, UK., Ottestad AL; Department of Oncology, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway.; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway., Yu J; GeneFirst Ltd, Building E5, Culham Science Centre, Abingdon, OX14 3DB, UK., Becker PW; GeneFirst Ltd, Building E5, Culham Science Centre, Abingdon, OX14 3DB, UK., Scaife S; GeneFirst Ltd, Building E5, Culham Science Centre, Abingdon, OX14 3DB, UK., Richman SD; Pathology and Data Analytics, Leeds Institute of Medical Research, University of Leeds, St James University Hospital, Leeds, LS9 7TF, UK., Wood HM; Pathology and Data Analytics, Leeds Institute of Medical Research, University of Leeds, St James University Hospital, Leeds, LS9 7TF, UK., Slaney H; Pathology and Data Analytics, Leeds Institute of Medical Research, University of Leeds, St James University Hospital, Leeds, LS9 7TF, UK., Bottomley D; Pathology and Data Analytics, Leeds Institute of Medical Research, University of Leeds, St James University Hospital, Leeds, LS9 7TF, UK., Yang X; Guangzhou Biotron Technology Co., Ltd, Room 204, Zone C, Science and Technology Innovation Base, No. 80, Lanyue Road, Science City, Guangzhou, China., Xiao H; Guangzhou Biotron Technology Co., Ltd, Room 204, Zone C, Science and Technology Innovation Base, No. 80, Lanyue Road, Science City, Guangzhou, China., Wahl SGF; Department of Oncology, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway.; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway., Grønberg BH; Department of Oncology, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway.; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway., Dai H; Department of Oncology, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway.; Department of Pathology, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway., Fu G; GeneFirst Ltd, Building E5, Culham Science Centre, Abingdon, OX14 3DB, UK. Guoliang.Fu@genefirst.com.

Publikováno v: Scientific reports [Sci Rep] 2021 Feb 04; Vol. 11 (1), pp. 3138. Date of Electronic Publication: 2021 Feb 04.

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Akademický článek

The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates.

Autor: Hinch AG; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK. Electronic address: anjali@well.ox.ac.uk., Becker PW; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Li T; Howard Hughes Medical Institute, Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA; Hefei National Laboratory for Physical Sciences at the Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Diseases, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, China., Moralli D; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Zhang G; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Bycroft C; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Green C; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Keeney S; Howard Hughes Medical Institute, Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA., Shi Q; Hefei National Laboratory for Physical Sciences at the Microscale, The CAS Key Laboratory of Innate Immunity and Chronic Diseases, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui, China., Davies B; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Donnelly P; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK; Department of Statistics, University of Oxford, Oxford, UK. Electronic address: donnelly@well.ox.ac.uk.

Publikováno v: Molecular cell [Mol Cell] 2020 Aug 20; Vol. 79 (4), pp. 689-701.e10. Date of Electronic Publication: 2020 Jun 30.

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Akademický článek

Factors influencing meiotic recombination revealed by whole-genome sequencing of single sperm.

Autor: Hinch AG; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Zhang G; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Becker PW; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Moralli D; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Hinch R; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.; Big Data Institute, University of Oxford, Oxford, UK., Davies B; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Bowden R; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Donnelly P; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK. donnelly@well.ox.ac.uk.; Department of Statistics, University of Oxford, Oxford, UK.

Publikováno v: Science (New York, N.Y.) [Science] 2019 Mar 22; Vol. 363 (6433).

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Akademický článek

Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development.

Autor: Sacilotto N; Ludwig Institute for Cancer Research Ltd, Nuffield Department of Clinical Medicine, University of Oxford, Oxford OX3 7DQ, United Kingdom., Monteiro R, Fritzsche M, Becker PW, Sanchez-Del-Campo L, Liu K, Pinheiro P, Ratnayaka I, Davies B, Goding CR, Patient R, Bou-Gharios G, De Val S

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2013 Jul 16; Vol. 110 (29), pp. 11893-8. Date of Electronic Publication: 2013 Jul 01.

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