Zobrazeno 1 - 10
of 1 396
pro vyhledávání: '"Beck‐Sickinger, Annette"'
Autor:
Tindall, Catherine A., Möhlis, Kevin, Rapöhn, Inka, Dommel, Sebastian, Riedl, Veronika, Schneekönig, Michael, Höfling, Corinna, Roßner, Steffen, Stichel, Jan, Beck-Sickinger, Annette G., Weiner, Juliane, Heiker, John T.
Vaspin is a serine protease inhibitor that protects against adipose tissueinflammation and insulin resistance, two key drivers of adipocyte dysfunc-tion and metabolic disorders in obesity. Inhibition of target proteases suchas KLK7 has been shown to
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A94162
https://ul.qucosa.de/api/qucosa%3A94162/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A94162/attachment/ATT-0/
Autor:
Vu, Oanh, Bender, Brian Joseph, Pankewitz, Lisa, Huster, Daniel, Beck-Sickinger, Annette G., Meiler, Jens
G protein-coupled receptors (GPCRs) represent the largest membrane protein family and a significant target class for therapeutics. Receptors from GPCRs’ largest class, class A, influence virtually every aspect of human physiology. About 45% of the
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A85301
https://ul.qucosa.de/api/qucosa%3A85301/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A85301/attachment/ATT-0/
Autor:
Spiller, Sabrina, Wippold, Tom, Bellmann-Sickert, Kathrin, Franz, Sandra, Saalbach, Anja, Anderegg, Ulf, Beck-Sickinger, Annette G.
Biomaterials are designed to improve impaired healing of injured tissue. To accomplish better cell integration, we suggest to coat biomaterial surfaces with bio-functional proteins. Here, a mussel-derived surface-binding peptide is used and coupled t
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A85360
https://ul.qucosa.de/api/qucosa%3A85360/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A85360/attachment/ATT-0/
Specifically addressing cell surface molecules on cancer cells facilitates targeted cancer therapies that offer the potential to selectively destroy malignant cells, while sparing healthy tissue. Thus, undesired side-effects in tumor patients are hig
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A85760
https://ul.qucosa.de/api/qucosa%3A85760/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A85760/attachment/ATT-0/
Autor:
Laugwitz, Jeannette M., Haeri, Haleh H., Kaiser, Anette, Krug, Ulrike, Hinderberger, Dariush, Beck-Sickinger, Annette G., Schmidt, Peter
The function of G protein-coupled receptors is intrinsically linked to their conformational dynamics. In conjugation with site-directed spin labeling, electron paramagnetic resonance (EPR) spectroscopy provides powerful tools to study the highly dyna
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A84842
https://ul.qucosa.de/api/qucosa%3A84842/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A84842/attachment/ATT-0/
Cancer became recently the leading cause of death in industrialized countries. Even though standard treatments achieve significant effects in growth inhibition and tumor elimination, they cause severe side effects as most of the applied drugs exhibit
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A84526
https://ul.qucosa.de/api/qucosa%3A84526/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A84526/attachment/ATT-0/
Autor:
Moldovan, Rares-Petru, Els-Heindl, Sylvia, Worm, Dennis J., Kniess, Torsten, Kluge, Michael, Beck-Sickinger, Annette G., Deuther-Conrad, Winnie, Krügel, Ute, Brust, Peter
The ghrelin receptor (GhrR) is a widely investigated target in several diseases. However, the current knowledge of its role and distribution in the brain is limited. Recently, the small and non-peptidic compound (S)-6-(4-bromo-2-fluorophenoxy)-3-((1-
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A88806
https://ul.qucosa.de/api/qucosa%3A88806/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A88806/attachment/ATT-0/
Autor:
Ansorge, Michael, Rastig, Nadine, Steinborn, Ralph, König, Tina, Baumann, Lars, Möller, Stephanie, Schnabelrauch, Matthias, Cross, Michael, Werner, Carsten, Beck-Sickinger, Annette, Pompe, Tilo
Cell fate decisions in many physiological processes, including embryogenesis, stem cell niche homeostasis and wound healing, are regulated by secretion of small signaling proteins, called cytokines, from source cells to their neighbors or into the en
Autor:
Ruggirello, Chiara, Mörl, Karin, Grüttner, Cordula, Teller, Henrik, Beck-Sickinger, Annette G.
Publikováno v:
In Journal of Organometallic Chemistry 1 August 2024 1016
Publikováno v:
In Neuropeptides June 2024 105