Zobrazeno 1 - 10
of 1 603
pro vyhledávání: '"Beck, Roy A."'
Intrinsically disordered proteins (IDPs) are a subset of proteins that lack stable secondary structure. Given their polymeric nature, previous mean-field approximations have been used to describe the statistical structure of IDPs. However, the amino-
Externí odkaz:
http://arxiv.org/abs/2311.18337
Autor:
Sethi, Vaishali, Cohen-Gerassi, Dana, Meir, Sagi, Ney, Max, Shmidov, Yulia, Koren, Gil, Adler-Abramovich, Lihi, Chilkoti, Ashutosh, Beck, Roy
The cornerstone of structural biology is the unique relationship between protein sequence and the 3D structure at equilibrium. Although intrinsically disordered proteins (IDPs) do not fold into a specific 3D structure, breaking this paradigm, some ID
Externí odkaz:
http://arxiv.org/abs/2309.00582
Autor:
Koren, Gil, Meir, Sagi, Holschuh, Lennard, Mertens, Haydyn D. T., Ehm, Tamara, Yahalom, Nadav, Golombek, Adina, Schwartz, Tal, Svergun, Dmitri I., Saleh, Omar A., Dzubiella, Joachim, Beck, Roy
Short-range interactions and long-range contacts drive the 3D folding of structured proteins. The proteins' structure has a direct impact on their biological function. However, nearly 40% of the eukaryotes proteome is composed of intrinsically disord
Externí odkaz:
http://arxiv.org/abs/2212.01894
Autor:
Freedman, Sharon F., Wallace, David K., Enyedi, Laura B., Prakalapakorn, Sasapin, Jones, Sarah K., Hug, Denise, Stahl, Erin D., Dent, Rebecca J., Kong, Lingkun, Wang, Serena, Gallerson, Bryan K., Hutchinson, Amy K., Lenhart, Phoebe, Brower, Judy, Morrison, David G., Ruark, Scott T., Mets-Halgrimson, Rebecca, Yoon, Hawke, Ralay-Ranaivo, Hantamalala, Hamidullah, Aaliyah, Areaux, Raymond, Anderson, Jill S., Holleschau, Ann M., Superstein, Rosanne, Belanger, Caroline, Fallaha, Nicole, Hamel, Patrick, Thibeault, Maryse, Tamkins, Susanna M., Chang, Ta, Park, Hee-Jung S., Trumler, Anya A., Liu, Xiaonong, Astle, William F., Sanders, Emi N., Traboulsi, Elias, Ghasia, Fatema, McOwen, Diana C., Gray, Michael E., Yang, Michael B., Bowman, Corey S., Galvin, Jennifer, Therriault, Margaret, Smith, Heather, Whitaker, Michele E., Orge, Faruk, Grigorian, Adriana P., Baird, Alicia M., Strominger, Mitchell B., Chen, Vicki, Klein, Shelley, Kemmer, Jacquelyn D., Neiman, Alexandra E., Mendoza, Myra N., Frohwein, Jill J., Bremer, Don, Cassady, Cybil, Golden, Richard, Jordan, Catherine, Rogers, David, Oravec, Sara A., Yanovitch, Tammy L., Lunsford, Keven, Nye, Christina, Shea, Caroline, Stillman, SueAnn M., LaRoche, G. Robert, Van Iderstine, Stephen C., Robertson, Elisa, Cruz, Oscar A., Ghadban, Rafif, Govreau, Dawn, Larson, Scott A., Longmuir, Susannah, Shan, Xiaoyan, Clarke, Michael P., Taylor, Kate, Powell, Christine, Hammond, Benjamin P., Gearinger, Matthew D., Czubinski, Andrea, Hendricks, Dorothy H., Jin, Jing, Salvin, Jonathan H., Fisher, Alicia, Lee, Katherine A., Brooks, Daniel, Schweinler, Bonita R., Sala, Nicholas A., Sala, Allyson M., Summers, Allison I., Karr, Daniel J., Wilson, Lorri B., Rauch, Paula K., O'Hara, Mary, Gandhi, Nandini, Hashmi, Tania, Colburn, Jeffrey, Dittman, Eileen, Whitfill, Charles R., Wheeler, Amy M., McCourt, Emily A., Singh, Jasleen, Welnick, Nanastasia, Azar, Nathalie F., Baker, Joseph, Droste, Patrick J., Peters, Robert J., Hilbrands, Jan, Pineles, Stacy L., Bernardo, Marianne J., Peterson, Edward, Peterson, Charla H., Kumar, Kartik, Melese, Ephrem, Lingua, Robert, Grijalva, Jeff, Crouch, Earl R., jr., Crouch, Earl R., III, Ventura, Gaylord, Anninger, William, Benson, Shawn L., Karp, Karen A., Smith, Jordana M., Brickman-Kelleher, Jill, Ticho, Benjamin H., Khammar, Alexander J., Clausius, Deborah A., Guo, Suquin, Suh, Donny, Chamberlain, Carolyn, Schloff, Susan, Madigan, William P., Burkman, Donna, Christiansen, Stephen P., Ramsey, Jean E., McConnell, Kate H., Friedman, Ilana, Rosado, Jose, Sauberan, Donald P., Hemberger, Jody C., Davis, Patricia L., Rudaitis, Indre, Lowery, Robert S., Cupit, Shawn, Bothun, Erick D., Mohney, Brian G., Wernimont, Suzanne M., Neilsen, Rebecca A., Herlihy, Erin P., Baran, Francine, Gladstone, Amy, Smith, Justin, Mellott, Mei, Kieser, Troy, Erzurum, S. Ayse, Colon, Beth, Shah, Birva, Quebbemann, Micaela, Beck, Roy W., Austin, Darrell S., Boyle, Nicole M., Conner, Courtney L., Chandler, Danielle L., Donahue, Quayleen, Fimbel, Brooke P., Robinson, Julianne L., Hercinovic, Amra, Hoepner, James E., Kaplon, Joseph D., Henderson, Robert J., Melia, B. Michele, Ortiz, Gillaine, Woodard, Victoria C., Stutz, Kathleen M., Sutherland, Desirae R., Wu, Rui, Everett, Donald F., Diener-West, Marie, Baker, John D., Davis, Barry, Phelps, Dale L., Poff, Stephen W., Saunders, Richard A., Tychsen, Lawrence, Bradfield, Yasmin S., Foster, Nicole C., Plager, David A., Salchow, Daniel J., Birch, Eileen E., Manny, Ruth E., Silver, Jayne L., Weise, Katherine K., Verderber, Lisa C., Repka, Michael X., Dean, Trevano W., Kraker, Raymond T., Li, Zhuokai, Yen, Kimberly G., de Alba Campomanes, Alejandra G., Young, Marielle P., Rahmani, Bahram, Haider, Kathryn M., Whitehead, George F., Lambert, Scott R., Kurup, Sudhi P., Kraus, Courtney L., Cotter, Susan A., Holmes, Jonathan M., Hatt, Sarah R., Traboulsi, Elias I.
Publikováno v:
In Ophthalmology October 2024 131(10):1196-1206
Autor:
Ekhlaspour, Laya, Buckingham, Bruce, Bauza, Colleen, Clements, Mark, Forlenza, Gregory P., Neyman, Anna, Norlander, Lisa, Schamberger, Marcus, Sherr, Jennifer L., Bailey, Ryan, Beck, Roy W., Kollman, Craig, Beasley, Shannon, Cobry, Erin, DiMeglio, Linda A., Paprocki, Emily, Van Name, Michelle, Moran, Antoinette
Publikováno v:
In Journal of Clinical & Translational Endocrinology June 2024 36
Autor:
Jacoby, Guy, Asher, Merav Segal, Ehm, Tamara, Ionita, Inbal Abutbul, Shinar, Hila, Azoulay-Ginsburg, Salome, Danino, Dganit, Kozlov, Michael M., Amir, Roey J., Beck, Roy
Publikováno v:
Journal of the American Chemical Society 143, 11879-11888 (2021)
Amphiphilic molecules and their self-assembled structures have long been the target of extensive research due to their potential applications in fields ranging from materials design to biomedical and cosmetic applications. Increasing demands for func
Externí odkaz:
http://arxiv.org/abs/2103.10131
Autor:
Hood, Korey K., Schneider-Utaka, Aika K., Reed, Zachariah W., Buckingham, Bruce A., Cobry, Erin, DeBoer, Mark D., Ekhlaspour, Laya, Schoelwer, Melissa, Paul Wadwa, R., Lum, John, Kollman, Craig, Beck, Roy W., Breton, Marc D.
Publikováno v:
In Diabetes Research and Clinical Practice February 2024 208
Autor:
Ehm, Tamara, Shinar, Hila, Meir, Sagi, Sekhon, Amandeep, Sethi, Vaishali, Morgan, Ian L., Rahamim, Gil, Saleh, Omar A., Beck, Roy
Publikováno v:
Nano Futures 5(2), 022501 (2021)
The human proteome is enriched in proteins that do not fold into a stable 3D structure. These intrinsically disordered proteins (IDPs) spontaneously fluctuate between a large number of configurations in their native form. Remarkably, the disorder doe
Externí odkaz:
http://arxiv.org/abs/2101.06902
Publikováno v:
PNAS, 2020
Characterizing the entropy of a system is a crucial, and often computationally costly, step in understanding its thermodynamics. It plays a key role in the study of phase transitions, pattern formation, protein folding and more. Current methods for e
Externí odkaz:
http://arxiv.org/abs/2008.05921
Glassy, nonexponential relaxations in globular proteins are typically attributed to conformational behaviors that are missing from intrinsically disordered proteins. Yet, we show that single molecules of a disordered-protein construct display two sig
Externí odkaz:
http://arxiv.org/abs/2007.10404