Tumor‐Cell‐Specific Targeting of Ibrutinib: Introducing Electrostatic Antibody‐Inhibitor Conjugates (AiCs).

Autor: Faust, Andreas, Bäumer, Nicole, Schlütermann, Alina, Becht, Manuel, Greune, Lilo, Geyer, Christiane, Rüter, Christian, Margeta, Renato, Wittmann, Lisa, Dersch, Petra, Lenz, Georg, Berdel, Wolfgang E., Bäumer, Sebastian

Publikováno v: Angewandte Chemie International Edition; 1/3/2022, Vol. 61 Issue 1, p1-11, 11p

Tumor-Cell-Specific Targeting of Ibrutinib: Introducing Electrostatic Antibody-Inhibitor Conjugates (AiCs).

Autor: Faust A; European Institute for Molecular Imaging, University of Münster, Waldeyerstr. 15, 48159, Münster, Germany.; Interdisciplinary Center of Clinical Research (IZKF), University of Münster, Albert-Schweitzer Campus 1, 48149, Münster, Germany., Bäumer N; Department of Medicine A, Hematology/Oncology, University Hospital Münster, Albert-Schweitzer Campus 1, 48149, Muenster, Germany.; Interdisciplinary Center of Clinical Research (IZKF), University of Münster, Albert-Schweitzer Campus 1, 48149, Münster, Germany., Schlütermann A; Department of Medicine A, Hematology/Oncology, University Hospital Münster, Albert-Schweitzer Campus 1, 48149, Muenster, Germany., Becht M; Department of Medicine A, Hematology/Oncology, University Hospital Münster, Albert-Schweitzer Campus 1, 48149, Muenster, Germany., Greune L; Institute for Infectiology, Center for Molecular Biology of Inflammation (ZMBE), University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany., Geyer C; Institute for Clinical Radiology, University Hospital Münster, Albert-Schweitzer Campus 1, 48149, Münster, Germany., Rüter C; Institute for Infectiology, Center for Molecular Biology of Inflammation (ZMBE), University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany., Margeta R; European Institute for Molecular Imaging, University of Münster, Waldeyerstr. 15, 48159, Münster, Germany., Wittmann L; Department of Medicine A, Hematology/Oncology, University Hospital Münster, Albert-Schweitzer Campus 1, 48149, Muenster, Germany., Dersch P; Institute for Infectiology, Center for Molecular Biology of Inflammation (ZMBE), University of Münster, Von-Esmarch-Str. 56, 48149, Münster, Germany., Lenz G; Department of Medicine A, Hematology/Oncology, University Hospital Münster, Albert-Schweitzer Campus 1, 48149, Muenster, Germany., Berdel WE; Department of Medicine A, Hematology/Oncology, University Hospital Münster, Albert-Schweitzer Campus 1, 48149, Muenster, Germany., Bäumer S; Department of Medicine A, Hematology/Oncology, University Hospital Münster, Albert-Schweitzer Campus 1, 48149, Muenster, Germany.; Interdisciplinary Center of Clinical Research (IZKF), University of Münster, Albert-Schweitzer Campus 1, 48149, Münster, Germany.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2022 Jan 03; Vol. 61 (1), pp. e202109769. Date of Electronic Publication: 2021 Nov 25.