The invariant chain CD74 protein is a cell surface binding partner of TIMP-1 in breast cancer cells.

Autor: Høeberg M; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.; Transport Biology section, Department of Plant and Environmental Sciences, University of Copenhagen, Denmark.; Sino-Danish Center for Education and Research (SDC), Aarhus University, Denmark., Noer JB; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Vistesen MV; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Bartels A; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Bech EM; Transport Biology section, Department of Plant and Environmental Sciences, University of Copenhagen, Denmark., Nygård SB; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Lademann U; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Stenvang J; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Liu S; Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China., Fuglsang AT; Transport Biology section, Department of Plant and Environmental Sciences, University of Copenhagen, Denmark., Brünner N; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Moreira JMA; Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

Publikováno v: Molecular oncology [Mol Oncol] 2023 Aug; Vol. 17 (8), pp. 1595-1612. Date of Electronic Publication: 2023 Apr 28.

Half-Life Extending Modifications of Peptide YY 3-36 Direct Receptor-Mediated Internalization.

Autor: Bech EM; Gubra Aps , Hørsholm , Denmark.; Department of Chemistry , University of Copenhagen , Frederiksberg , Denmark., Kaiser A; Institute of Biochemistry, Faculty of Life Sciences , Leipzig University , Leipzig , Germany., Bellmann-Sickert K; Institute of Biochemistry, Faculty of Life Sciences , Leipzig University , Leipzig , Germany., Nielsen SS; Department of Chemistry , University of Copenhagen , Frederiksberg , Denmark., Sørensen KK; Department of Chemistry , University of Copenhagen , Frederiksberg , Denmark., Elster L; Gubra Aps , Hørsholm , Denmark., Hatzakis N; Department of Chemistry , University of Copenhagen , Frederiksberg , Denmark.; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences , University of Copenhagen , Frederiksberg , Denmark., Pedersen SL; Gubra Aps , Hørsholm , Denmark., Beck-Sickinger AG; Institute of Biochemistry, Faculty of Life Sciences , Leipzig University , Leipzig , Germany., Jensen KJ; Department of Chemistry , University of Copenhagen , Frederiksberg , Denmark.

Publikováno v: Molecular pharmaceutics [Mol Pharm] 2019 Aug 05; Vol. 16 (8), pp. 3665-3677. Date of Electronic Publication: 2019 Jul 25.

Chemical Strategies for Half-Life Extension of Biopharmaceuticals: Lipidation and Its Alternatives.

Autor: Bech EM; Department of Chemistry, University of Copenhagen, Frederiksberg DK-1871, Denmark.; Gubra Aps, Hørsholm DK-2970, Denmark., Pedersen SL; Gubra Aps, Hørsholm DK-2970, Denmark., Jensen KJ; Department of Chemistry, University of Copenhagen, Frederiksberg DK-1871, Denmark.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2018 Jun 15; Vol. 9 (7), pp. 577-580. Date of Electronic Publication: 2018 Jun 15 (Print Publication: 2018).

Neoglycolipids for Prolonging the Effects of Peptides: Self-Assembling Glucagon-like Peptide 1 Analogues with Albumin Binding Properties and Potent in Vivo Efficacy.

Autor: van Witteloostuijn SB; Gubra ApS , Hørsholm Kongevej 11B, 2970 Hørsholm, Denmark.; Department of Chemistry, Faculty of Science, University of Copenhagen , Thorvaldsensvej 40, 1871 Frederiksberg C, Denmark., Mannerstedt K; Gubra ApS , Hørsholm Kongevej 11B, 2970 Hørsholm, Denmark., Wismann P; Gubra ApS , Hørsholm Kongevej 11B, 2970 Hørsholm, Denmark.; Department of Clinical Medicine, Faculty of Health Science, University of Copenhagen , Blegdamsvej 9, 2100 København Ø, Denmark., Bech EM; Gubra ApS , Hørsholm Kongevej 11B, 2970 Hørsholm, Denmark.; Department of Chemistry, Faculty of Science, University of Copenhagen , Thorvaldsensvej 40, 1871 Frederiksberg C, Denmark., Thygesen MB; Department of Chemistry, Faculty of Science, University of Copenhagen , Thorvaldsensvej 40, 1871 Frederiksberg C, Denmark., Vrang N; Gubra ApS , Hørsholm Kongevej 11B, 2970 Hørsholm, Denmark., Jelsing J; Gubra ApS , Hørsholm Kongevej 11B, 2970 Hørsholm, Denmark., Jensen KJ; Department of Chemistry, Faculty of Science, University of Copenhagen , Thorvaldsensvej 40, 1871 Frederiksberg C, Denmark., Pedersen SL; Gubra ApS , Hørsholm Kongevej 11B, 2970 Hørsholm, Denmark.

Publikováno v: Molecular pharmaceutics [Mol Pharm] 2017 Jan 03; Vol. 14 (1), pp. 193-205. Date of Electronic Publication: 2016 Dec 22.