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Essential Omega-3 Fatty Acids Tune Microglial Phagocytosis of Synaptic Elements in the Mouse Developing Brain

Autor: Madore, C., Leyrolle, Q., Morel, L., Rossitto, M., Greenhalgh, A., Delpech, J., Martinat, M., Bosch-Bouju, C., Bourel, J., Rani, B., Lacabanne, C., Thomazeau, A., Hopperton, K., Beccari, S., Sere, A., Aubert, A., De Smedt-Peyrusse, V., Lecours, C., Bisht, K., Fourgeaud, L., Grégoire, Stéphane, Brétillon, Lionel, Acar, Niyazi, Grant, N., Badaut, J., Gressens, P., Sierra, A., Butovsky, O., Tremblay, M., Bazinet, R., Joffre, Corinne, Nadjar, Agnès, Layé, Sophie

Publikováno v: Addi. Archivo Digital para la Docencia y la Investigación
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Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-19861-z⟩
Madore, C, Leyrolle, Q, Morel, L, Rossitto, M, Greenhalgh, A D, Delpech, J C, Martinat, M, Bosch-bouju, C, Bourel, J, Rani, B, Lacabanne, C, Thomazeau, A, Hopperton, K E, Beccari, S, Sere, A, Aubert, A, De Smedt-peyrusse, V, Lecours, C, Bisht, K, Fourgeaud, L, Gregoire, S, Bretillon, L, Acar, N, Grant, N J, Badaut, J, Gressens, P, Sierra, A, Butovsky, O, Tremblay, M E, Bazinet, R P, Joffre, C, Nadjar, A & Layé, S 2020, ' Essential omega-3 fatty acids tune microglial phagocytosis of synaptic elements in the mouse developing brain ', Nature Communications, vol. 11, no. 1, 6133 . https://doi.org/10.1038/s41467-020-19861-z
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.6133. ⟨10.1038/s41467-020-19861-z⟩

Omega-3 fatty acids (n-3 PUFAs) are essential for the functional maturation of the brain. Westernization of dietary habits in both developed and developing countries is accompanied by a progressive reduction in dietary intake of n-3 PUFAs. Low matern

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8aa9df3a679021c0444c654f792af58f
http://hdl.handle.net/10810/50869

Coupled proliferation and apoptosis maintain the rapid turnover of microglia in the adult brain

Autor: Askew, K, Li, K, Olmos-Alonso, A, Garcia-Moreno, F, Liang, Y, Richardson, P, Tipton, T, Chapman, MA, Riecken, K, Beccari, S, Sierra, A, Molnár, Z, Cragg, MS, Garaschuk, O, Perry, VH, Gomez-Nicola, D

Publikováno v: Cell Reports, Vol 18, Iss 2, Pp 391-405 (2017)
Cell Reports

Summary Microglia play key roles in brain development, homeostasis, and function, and it is widely assumed that the adult population is long lived and maintained by self-renewal. However, the precise temporal and spatial dynamics of the microglial po

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::38f624411895610945aaab118c33898e
https://eprints.soton.ac.uk/403985/

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