Výsledky vyhledávání - "Beazley-Long N"

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Diabetes‐induced microvascular complications at the level of the spinal cord: a contributing factor in diabetic neuropathic pain

Autor: Ved, N., Da Vitoria Lobo, M. E., Bestall, S. M., L. Vidueira, C., Beazley‐Long, N., Ballmer‐Hofer, K., Hirashima, M., Bates, D. O., Donaldson, L. F., Hulse, R. P.

Publikováno v: The Journal of Physiology

Key points Diabetes is thought to induce neuropathic pain through activation of dorsal horn sensory neurons in the spinal cord.Here we explore the impact of hyperglycaemia on the blood supply supporting the spinal cord and chronic pain development.In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::160f29084d6ff98706c8516a42638ede
http://europepmc.org/articles/PMC6092307

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Vybrat výsledek číslo 3 3

Sensory neuronal sensitisation occurs through HMGB-1/RAGE and TRPV1 in high glucose conditions

Autor: Bestall, SM, Hulse, RP, Blackley, Z, Swift, M, Ved, N, Paton, K, Beazley-Long, N, Bates, DO, Donaldson, LF

Many potential causes for painful diabetic neuropathy have been proposed including actions of cytokines and growth factors. High mobility group protein B1 (HMGB1) is a RAGE agonist, increased in diabetes, that contributes to pain by modulating periph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::a06e7f6c830ecac6fb6def21dd056e6c
https://irep.ntu.ac.uk/id/eprint/33909/7/11424_a995_Hulse.pdf

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Vybrat výsledek číslo 4 4

Akademický článek

Quantification of Angiogenesis in Laser Choroidal Neovascularization.

Autor: Green KR; Endothelial Quiescence Group, Centre for Cancer Sciences, Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, UK., Beazley-Long N; Endothelial Quiescence Group, Centre for Cancer Sciences, Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, UK., Lynch AP; Endothelial Quiescence Group, Centre for Cancer Sciences, Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, UK., Allen CL; Exonate Ltd, Nottingham, UK., Bates DO; Tumour and Vascular Biology Laboratories, Centre for Cancer Sciences, School of Medicine, Biodiscovery Institute, University of Nottingham, Nottingham, UK., Benest AV; Endothelial Quiescence Group, Centre for Cancer Sciences, Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, UK. Andrew.Benest@nottingham.ac.uk.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2441, pp. 223-231.

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Vybrat výsledek číslo 5 5

Akademický článek

Simple Gene Knockdown in Endothelial Cells Using Short Interfering RNA Oligonucleotides.

Autor: Tabrizi ZB; Endothelial Quiescence Group, Centre for Cancer Sciences, Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, UK., Green KR; Endothelial Quiescence Group, Centre for Cancer Sciences, Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, UK., Lynch AP; Endothelial Quiescence Group, Centre for Cancer Sciences, Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, UK., Ahmed NS; Endothelial Quiescence Group, Centre for Cancer Sciences, Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, UK., Beazley-Long N; Endothelial Quiescence Group, Centre for Cancer Sciences, Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, UK., Benest AV; Endothelial Quiescence Group, Centre for Cancer Sciences, Biodiscovery Institute, School of Medicine, University of Nottingham, Nottingham, UK. Andrew.Benest@nottingham.ac.uk.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2022; Vol. 2441, pp. 251-255.

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Vybrat výsledek číslo 6 6

Akademický článek

Bioinspired artificial exosomes based on lipid nanoparticles carrying let-7b-5p promote angiogenesis in vitro and in vivo.

Autor: Aday S; Bristol Heart Institute, University of Bristol, Bristol BS2 8ED, UK; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA., Hazan-Halevy I; Laboratory of Precision NanoMedicine, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel., Chamorro-Jorganes A; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK., Anwar M; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK., Goldsmith M; Laboratory of Precision NanoMedicine, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel., Beazley-Long N; Biodiscovery Institute, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG7 2RD, UK., Sahoo S; Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Dogra N; Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Sweaad W; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK., Catapano F; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK., Ozaki-Tan S; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK., Angelini GD; Bristol Heart Institute, University of Bristol, Bristol BS2 8ED, UK., Madeddu P; Bristol Heart Institute, University of Bristol, Bristol BS2 8ED, UK., Benest AV; Biodiscovery Institute, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG7 2RD, UK., Peer D; Laboratory of Precision NanoMedicine, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel. Electronic address: peer@tauex.tau.ac.il., Emanueli C; Bristol Heart Institute, University of Bristol, Bristol BS2 8ED, UK; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK. Electronic address: c.emanueli@imperial.ac.uk.

Publikováno v: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2021 Jul 07; Vol. 29 (7), pp. 2239-2252. Date of Electronic Publication: 2021 Mar 18.

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Vybrat výsledek číslo 7 7

Akademický článek

Paclitaxel alters the microvascular network in the central and peripheral nervous system of rats with chemotherapy-induced painful peripheral neuropathy.

Autor: Zippo AG; Institute of Neuroscience, Consiglio Nazionale delle Ricerche, Monza, Italy., Rodriguez-Menendez V; Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; NeuroMI (Milan Center for Neuroscience), Milan, Italy., Pozzi E; Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; NeuroMI (Milan Center for Neuroscience), Milan, Italy., Canta A; Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; NeuroMI (Milan Center for Neuroscience), Milan, Italy., Chiorazzi A; Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; NeuroMI (Milan Center for Neuroscience), Milan, Italy., Ballarini E; Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; NeuroMI (Milan Center for Neuroscience), Milan, Italy., Monza L; Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; NeuroMI (Milan Center for Neuroscience), Milan, Italy., Alberti P; Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; NeuroMI (Milan Center for Neuroscience), Milan, Italy.; Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Meregalli C; Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; NeuroMI (Milan Center for Neuroscience), Milan, Italy., Bravin A; Physics Department, University of Milano-Bicocca, Milan, Italy., Coan P; Faculty of Physics, Ludwig-Maximillian University, Munich, Germany., Longo E; Elettra-Sincrotrone Trieste S.C.p.A, Trieste, Italy., Saccomano G; Elettra-Sincrotrone Trieste S.C.p.A, Trieste, Italy.; Department of Architecture and Engineering, University of Trieste, Trieste, Italy., Paiva K; Laboratory of Applied Physics to Biomedical Science, Physics Institute, Rio de Janeiro State University, Rio de Janeiro, Brazil., Tromba G; Elettra-Sincrotrone Trieste S.C.p.A, Trieste, Italy., Cavaletti G; Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; NeuroMI (Milan Center for Neuroscience), Milan, Italy.; Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy., Carozzi VA; Experimental Neurology Unit, School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; NeuroMI (Milan Center for Neuroscience), Milan, Italy.

Publikováno v: Journal of the peripheral nervous system : JPNS [J Peripher Nerv Syst] 2024 Oct 22. Date of Electronic Publication: 2024 Oct 22.

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Vybrat výsledek číslo 8 8

Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia

Autor: Hulse, RP, Beazley-Long, N, Hua, J, Kennedy, H, Prager, J, Bevan, H, Qiu, Y, Fernandes, ES, Gammons, MV, Ballmer-Hofer, K, Gittenberger de Groot, AC, Churchill, AJ, Harper, SJ, Brain, SD, Bates, DO, Donaldson, LF

Publikováno v: Neurobiology of Disease
Neurobiology of disease
Neurobiology of Disease, Vol 71, Iss, Pp 245-259 (2014)

Vascular endothelial growth factor-A (VEGF-A) is best known as a key regulator of the formation of new blood vessels. Neutralization of VEGF-A with anti-VEGF therapy e.g. bevacizumab, can be painful, and this is hypothesized to result from a loss of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7fa2bec7cc98cb18599b1a718cb8f5cf
https://pubmed.ncbi.nlm.nih.gov/25151644

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Vybrat výsledek číslo 9 9

Akademický článek

Extracellular vesicles carry transcriptional 'dark matter' revealing tissue‐specific information.