Zobrazeno 1 - 10
of 177
pro vyhledávání: '"Beatriz Tuchweber"'
Phosphatidylcholine-enriched diet prevents gallstone formation in mice susceptible to cholelithiasis
Autor:
Joelle Kasbo, Beatriz Tuchweber, Shahid Perwaiz, Guylaine Bouchard, Huguette Lafont, Nicole Domingo, Francoise Chanussot, Ibrahim M. Yousef
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 12, Pp 2297-2303 (2003)
Cholesterol gallstones affect approximately 10–15% of the adult population in North America. Phosphatidylcholine (PC) is considered to be the main cholesterol solubilizer in bile. This study examined the effect of a PC-enriched diet on gallstone in
Externí odkaz:
https://doaj.org/article/04a9ae9311fe479dbb9de1083e341b33
Autor:
Shahid Perwaiz, Dana Forrest, Diane Mignault, Beatriz Tuchweber, M.James Phillip, Renxue Wang, Victor Ling, Ibrahim M. Yousef
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 3, Pp 494-502 (2003)
Bile formation and its canalicular secretion are essential functions of the mammalian liver. The sister-of-p-glycoprotein (spgp) gene was shown to encode the canalicular bile salt export protein, and mutations in spgp gene were identified as the caus
Externí odkaz:
https://doaj.org/article/26f28618442b4c10a09ca20358f9df3e
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 1, Pp 114-119 (2001)
A simple, sensitive, and specific liquid chromatography-electrospray tandem mass spectrometry (LC-MS/MS) method for the determination of bile acids in human bile has been developed. The bile acids were extracted with a C18 (octadecyl) reversed-phase
Externí odkaz:
https://doaj.org/article/af3ed416bf874802b54e2211215282ae
Autor:
Ibrahim M. Yousef, Dominique C. Belli, Lyse-Andrée Fournier, Claude C. Roy, Robert Giguère, Beatriz Tuchweber
Publikováno v:
Liver. 11:162-169
The present study was aimed at determining whether the protection by taurine of lithocholate-sulfate-induced cholestasis is mediated by conjugation or by direct effect of the amino acid on bile formation. Injection of free and conjugated (glycine and
Publikováno v:
Liver. 7:130-137
— In some cholestatic syndromes, lithocholic acid (LCA) has been identified in serum and bile and might play a role in the pathogenesis of cholestasis. Thus, we examined the effect of chronic LCA administration on hepatobiliary function in rats. Th
Phosphatidylcholine-enriched diet prevents gallstone formation in mice susceptible to cholelithiasis
Autor:
Beatriz Tuchweber, Guylaine Bouchard, Nicole Domingo, Huguette Lafont, Shahid Perwaiz, Ibrahim M. Yousef, Françoise Chanussot, Joelle Kasbo
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 12, Pp 2297-2303 (2003)
Cholesterol gallstones affect approximately 10-15% of the adult population in North America. Phosphatidylcholine (PC) is considered to be the main cholesterol solubilizer in bile. This study examined the effect of a PC-enriched diet on gallstone inci
Publikováno v:
Pharmacological Research. 48:467-472
The inhibition of canalicular glycoprotein transporters has been suggested as the cause of familial intrahepatic cholestasis. Mutations in multidrug resistance 3-glycoprotein (MDR3) gene induce progressive familial intrahepatic cholestasis type 3 (PF
Autor:
Ibrahim M. Yousef, Dana Forrest, M.James Phillip, Beatriz Tuchweber, Ren-Xue Wang, Victor Ling, Diane Mignault, Shahid Perwaiz
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 3, Pp 494-502 (2003)
Bile formation and its canalicular secretion are essential functions of the mammalian liver. The sister-of-p-glycoprotein (spgp) gene was shown to encode the canalicular bile salt export protein, and mutations in spgp gene were identified as the caus
Autor:
Ibrahim M. Yousef, Beatriz Tuchweber, Jean Rosenbaum, Alexis Desmoulière, Thierry Lamireau, Emile Levy, Monica Zoltowska
Publikováno v:
Life Sciences. 72:1401-1411
Hydrophobic bile acids, which are known to be cytotoxic for hepatocytes, are retained in high amount in the liver during cholestasis. Thus, we have investigated the effects of bile acids with various hydrophobicities on biliary epithelial cells. Bili
Publikováno v:
Lipids. 37:1093-1100
A simple method for the determination of bile acids in adult human fecal samples using GC-MS is described. Bile acids are directly extracted from feces by ethanol (95%) containing 0.1 N NaOH. Extracts are purified by passage through a reversed-phase