Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Beatriz Martinez Delgado"'
Autor:
Evrim Ercetin, Sarah Richtmann, Beatriz Martinez Delgado, Gema Gomez-Mariano, Sabine Wrenger, Elena Korenbaum, Bin Liu, David DeLuca, Mark P. Kühnel, Danny Jonigk, Kadriya Yuskaeva, Arne Warth, Thomas Muley, Hauke Winter, Michael Meister, Tobias Welte, Sabina Janciauskiene, Marc A. Schneider
Publikováno v:
Cancers, Vol 11, Iss 9, p 1306 (2019)
Abstract: High expression of SERPINA1 gene encoding acute phase protein, alpha1-antitrypsin (AAT), is associated with various tumors. We sought to examine the significance of SERPINA1 and AAT protein in non-small-cell lung cancer (NSCLC) patients and
Externí odkaz:
https://doaj.org/article/5aa68ba869d64397955f1f9d6c45e007
Autor:
Nupur Aggarwal, Beatriz Martinez Delgado, Sandeep Salipalli, Nerea Matamala, Jessica Rademacher, Nicolaus Schwerk, Tobias Welte, Sabina Janciauskiene, Felix C. Ringshausen
Publikováno v:
ERJ Open Research, Vol 2, Iss 2 (2016)
Externí odkaz:
https://doaj.org/article/41274e33544847848d5b190b140d5e51
Autor:
Anna Ricarda Gründing, Marc A. Schneider, Sarah Richtmann, Mark Kriegsmann, Hauke Winter, Beatriz Martinez-Delgado, Sarai Varona, Bin Liu, David S. DeLuca, Julia Held, Sabine Wrenger, Thomas Muley, Michael Meister, Tobias Welte, Sabina Janciauskiene
Publikováno v:
Cancers, Vol 14, Iss 18, p 4454 (2022)
To explore the relationship between cancer cell SREBF1 expression, lipid droplets (LDs) formation, and the sensitivity to chemotherapies, we cultured lung adenocarcinoma cells H1299 (with LD) and H1563 (without LD) in a serum-free basal medium (BM) o
Externí odkaz:
https://doaj.org/article/f852546b8ad847888c1b59c978aceee7
Autor:
Sri Harsha Meghadri, Beatriz Martinez-Delgado, Lena Ostermann, Gema Gomez-Mariano, Sara Perez-Luz, Srinu Tumpara, Sabine Wrenger, David S. DeLuca, Ulrich A. Maus, Tobias Welte, Sabina Janciauskiene
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10425 (2022)
The SERPINA1 gene encodes alpha1-antitrypsin (AAT), an acute phase glycoprotein and serine protease inhibitor that is mainly (80–90%) produced in the liver. Point mutations in the SERPINA1 gene can lead to the misfolding, intracellular accumulation
Externí odkaz:
https://doaj.org/article/48d305f6a2924b23942ec8d212f89cd8
Autor:
Kokilavani Sivaraman, Sabine Wrenger, Bin Liu, Dirk Schaudien, Christina Hesse, Gema Gomez-Mariano, Sara Perez-Luz, Katherina Sewald, David DeLuca, Maria J Wurm, Paco Pino, Tobias Welte, Beatriz Martinez-Delgado, Sabina Janciauskiene
Publikováno v:
Journal of Leukocyte Biology. 113:58-70
Rodent models of lipopolysaccharide (LPS)–induced pulmonary inflammation are used for anti-inflammatory drug testing. We aimed to characterize mice responses to aerosolized LPS alone or with intraperitoneal (i.p.) delivery of alpha1-antitrypsin (AA
Autor:
Srinu Tumpara, Elena Korenbaum, Mark Kühnel, Danny Jonigk, Beata Olejnicka, Michael Davids, Tobias Welte, Beatriz Martinez-Delgado, Sabina Janciauskiene
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 4, p 2141 (2021)
The C-terminal-fragments of alpha1-antitrypsin (AAT) have been identified and their diverse biological roles have been reported in vitro and in vivo. These findings prompted us to develop a monoclonal antibody that specifically recognizes C-36 peptid
Externí odkaz:
https://doaj.org/article/5d20ba96e6f9436aaaf918acd73178de
Autor:
Miljana Tanić, Kira Yanowski, Eduardo Andrés, Gonzalo Gómez-López, María Rodríguez-Pinilla Socorro, David G. Pisano, Beatriz Martinez-Delgado, Javier Benítez
Publikováno v:
Genomics Data, Vol 3, Iss C, Pp 75-79 (2015)
Hereditary breast cancer constitutes only 5–10% of all breast cancer cases and is characterized by strong family history of breast and/or other associated cancer types. Only ~25% of hereditary breast cancer cases carry a mutation in BRCA1 or BRCA2
Externí odkaz:
https://doaj.org/article/1d03e567d9e24ed4906c2e45465e67ed
Autor:
Sri Harsha, Meghadri, Beatriz, Martinez-Delgado, Lena, Ostermann, Gema, Gomez-Mariano, Sara, Perez-Luz, Srinu, Tumpara, Sabine, Wrenger, David S, DeLuca, Ulrich A, Maus, Tobias, Welte, Sabina, Janciauskiene
Publikováno v:
International journal of molecular sciences. 23(18)
The
Autor:
Nerea Matamala, Nupur Aggarwal, Paolo Iadarola, Marco Fumagalli, Gema Gomez-Mariano, Beatriz Lara, Maria Teresa Martinez, Isabel Cuesta, Jan Stolk, Sabina Janciauskiene, Beatriz Martinez-Delgado
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0170533 (2017)
Human SERPINA1 gene is located on chromosome 14q31-32.3 and is organized into three (IA, IB, and IC) non-coding and four (II, III, IV, V) coding exons. This gene produces α1-antitrypsin (A1AT), a prototypical member of the serpin superfamily of prot
Externí odkaz:
https://doaj.org/article/112785c93e014fe7b90637f2c6e34734
Publikováno v:
Epigenomes. 6(3)
Rare diseases affect more than 300 million people worldwide. Diagnosing rare diseases is a major challenge as they have different causes and etiologies. Careful assessment of clinical symptoms often leads to the testing of the most common genetic alt