Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Beatriz Malvar-Fernandez"'
Autor:
Carlos Rafael-Vidal, Sara Martínez-Ramos, Beatriz Malvar-Fernández, Irene Altabás-González, Coral Mouriño, Pablo Pazos-López, Arturo Fraga-Bau, José María Pego Reigosa, Samuel García
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-9 (2024)
Abstract Introduction Endothelial progenitor cells (EPCs) are essential for maintenance of vascular homeostasis and stability, key processes in the pathogenesis of systemic lupus erythematosus (SLE). However, the role and phenotypic characterization
Externí odkaz:
https://doaj.org/article/3a1229f0566d4f56b1bed14b936866f7
Autor:
Beatriz Malvar Fernandez, Weiyang Tao, Sandra C Silva-Cardoso, Marianne Boes, Timothy R D J Radstake, Aridaman Pandit
Publikováno v:
European Journal of Immunology
RNA sequencing and DNA methylomic profiling were performed after differentiating monocytes for 6 days into moDCs with/without CXCL4 presence. We show that CXCL4 downregulates genes associated with tolerogenicity in DCs including C1Q. Expression profi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f2541e22c3c5efcbfbef64d80394db
https://doi.org/10.1002/eji.201948341
https://doi.org/10.1002/eji.201948341
Autor:
Kris A. Reedquist, Andrea Ottria, Wioleta Marut, Beatriz Malvar Fernandez, Timothy R D J Radstake, Samuel Garcia, Barbara Giovannone, Tiago Carvalheiro
Publikováno v:
Rheumatology (Oxford, England)
Objectives SSc is an autoimmune disease characterized by inflammation, vascular injury and excessive fibrosis in multiple organs. Secreted protein acidic and rich in cysteine (SPARC) is a matricellular glycoprotein that regulates processes involved i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65fac3a8ef9c0316706ebe5116e70a4
https://doi.org/10.1093/rheumatology/kez583
https://doi.org/10.1093/rheumatology/kez583
Autor:
Wioleta Marut, Tiago Carvalheiro, Femke Bonte-Mineur, Jose M Pego-Reigosa, Beatriz Malvar-Fernandez, Carlos Rafael-Vidal, Timothy R D J Radstake, Maili Zimmermann, Maarten van der Kroef, Lorenzo Beretta, Samuel Garcia, Anneline C Hinrichs, Marc R. Kok, Ana P Lopes, Nila H. Servaas
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9544, p 9544 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 24
International Journal of Molecular Sciences
Volume 21
Issue 24
Angiopoietin-2 (Ang-2), a ligand of the tyrosine kinase receptor Tie2, is essential for vascular development and blood vessel stability and is also involved in monocyte activation. Here, we examined the role of Ang-2 on monocyte activation in patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::923bd789c7b899285ec89dd16c72a52b
https://www.mdpi.com/1422-0067/21/24/9544
https://www.mdpi.com/1422-0067/21/24/9544
Autor:
Beatriz Malvar-Fernandez, Carlos Rafael-Vidal, Timothy R D J Radstake, Tiago Carvalheiro, Samuel Garcia, Jose M Pego-Reigosa, Ana P Lopes
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 6965, p 6965 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 18
International Journal of Molecular Sciences
Volume 21
Issue 18
Semaphorin (Sema)4A is a transmembrane glycoprotein that is elevated in several autoimmune diseases such as systemic sclerosis, rheumatoid arthritis and multiple sclerosis. Sema4A has a key role in the regulation of Thelper Th1 and Th2 differentiatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01064f1e1b8138633760ed1d281aff1e
https://www.mdpi.com/1422-0067/21/18/6965
https://www.mdpi.com/1422-0067/21/18/6965
Autor:
Samuel Garcia, Pablo Pazos-López, Jose Maria Pego Reigosa, Irene Altabás-González, Carlos Rafael-Vidal, Sara Martínez-Ramos, Beatriz Malvar-Fernández, Coral Mouriño, Arturo Fraga-Bau
Publikováno v:
Lupus Science and Medicine, Vol 11, Iss Suppl 1 (2024)
Externí odkaz:
https://doaj.org/article/061fea19a4f845d0a16c1f2c299473c4
Autor:
Sara Martínez-Ramos, Carlos Rafael-Vidal, Beatriz Malvar-Fernández, Nair Pérez, Coral Mouriño, Sara García Pérez, Francisco J. Maceiras Pan, Carmen Conde, Jose María Pego-Reigosa, Samuel García
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
Previous works from our group show that Semaphorin3B (Sema3B) is reduced in RA and plays a protective role in a mouse arthritis model. In turn, MerTK plays a protective function in murine arthritis models, is expressed by synovial tissue macrophages
Externí odkaz:
https://doaj.org/article/b9e591aa48c64c3a9bf22b54fbffe83d
Autor:
Carlos Rafael-Vidal, Sara Martínez-Ramos, Beatriz Malvar-Fernández, Irene Altabás-González, Coral Mouriño, Douglas J. Veale, Achilleas Floudas, Ursula Fearon, José María Pego Reigosa, Samuel García
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Endothelial cell (EC) dysfunction is a hallmark of Systemic Lupus Erythematosus (SLE) and Tie2 is a receptor essential for vascular stability. Inflammatory processes promote inhibition of Tie2 homeostatic activation, driving vascular dysfunction. In
Externí odkaz:
https://doaj.org/article/8581c997c1614d2199f85464775b57a8
Autor:
Ellen van Lochem, Femke van Wijk, Kris A. Reedquist, Bas Oldenburg, Elly van Koolwijk, Eelco C. Brand, Lisanne Lutter, Beatriz Malvar Fernandez, Britt Roosenboom, Carmen S Horjus Talabur Horje
Publikováno v:
Gastroenterology. 158:S-1031
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3e2ac6993560fbecfb02db3d47bd262
https://doi.org/10.1016/s0016-5085(20)33256-x
https://doi.org/10.1016/s0016-5085(20)33256-x