Antifungal Activity Directed Toward the Cell Wall by 2-Cyclohexylidenhydrazo- 4-Phenyl-Thiazole Against Candida albicans

Autor: Cleudiomar Inácio Lino, Susana Johann, Ana Paula Possa, Carlos A. Rosa, Beth Burgwyn Fuchs, Nayara Cristina Fonseca, Renata Barbosa de Oliveira, Jaqueline Maria Siqueira Ferreira, Nívea Pereira de Sá, Pilar Pérez, Eleftherios Mylonakis, Lana Ivone Barreto Cruz, Beatriz M. Borelli

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

[Background] The increasing incidence of invasive forms of candidiasis and resistance to antifungal therapy leads us to seek new and more effective antifungal compounds. Objectives: To investigate the antifungal activity and toxicity as well as to ev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6a17a98b43e1ddfaf735c779119a89
https://doi.org/10.2174/1871526518666180531101605

Spathaspora boniae sp. nov., a D-xylose-fermenting species in the Candida albicans/Lodderomyces clade

Autor: Glória Regina Franco, Thiago M. Batista, Jacek Kominek, Camila G. Morais, Luiz H. Rosa, Carlos A. Rosa, Carolina Furtado, Marc-André Lachance, Chris Todd Hittinger, Beatriz M. Borelli, Rennan G. Moreira, César Fonseca

Publikováno v: Morais, C G, Batista, T M, Kominek, J, Borelli, B M, Furtado, C, Moreira, R G, Franco, G R, Rosa, L H, Fonseca, C, Hittinger, C T, Lachance, M A & Rosa, C A 2017, ' Spathaspora boniae sp. nov., a D-xylose-fermenting species in the Candida albicans/lodderomyces clade ', International Journal of Systematic and Evolutionary Microbiology, vol. 67, no. 10, 002186, pp. 3798-3805 . https://doi.org/10.1099/ijsem.0.002186

Two yeast isolates producing asci-containing elongate ascospores with curved ends typical of the genus Spathaspora were isolated from rotting wood samples collected in an Atlantic rainforest ecosystem in Brazil. Phylogenetic analysis of the LSU rRNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66c072c2e9ad676952c02c9f004ca3a
https://doi.org/10.1099/ijsem.0.002186

Occurrence, antifungal susceptibility, and virulence factors of opportunistic yeasts isolated from Brazilian beaches

Autor: Sona Kucharikova, Patrick Van Dijck, Carlos A. Rosa, Natália O. P. Maciel, Daniel Assis Santos, Camila G. Morais, Beatriz M. Borelli, Luciana R. Brandão, Gustavo Jc Freitas, Franciane Pellizzari, Alexandre Penido de Oliveira, Susana Johann

Publikováno v: Memórias do Instituto Oswaldo Cruz, Volume: 114, Article number: e180566, Published: 14 MAR 2019
Memórias do Instituto Oswaldo Cruz
Memórias do Instituto Oswaldo Cruz., Vol 114, Iss 0 (2019)

BACKGROUND Opportunistic pathogenic yeast species are frequently associated with water habitats that have pollution sources of human or animal origin. Candida albicans has already been suggested as a faecal indicator microorganism for aquatic environ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3c76efd459f34b3e0fd5e796e077ad
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762019000100315&lng=en&tlng=en

Synthesis, molecular modeling studies and evaluation of antifungal activity of a novel series of thiazole derivatives

Autor: Vinícius Gonçalves Maltarollo, Susana Johann, Elaine Maria de Souza Fagundes, Beatriz M. Borelli, Thelma Tirone Silvério Matos, Renata Barbosa de Oliveira, Iasmin Natália Santos Teixeira, Jonas Pereira Ramos, Cleudiomar Inácio Lino, Philipe de Oliveira Fernandes, Igor Gonçalves de Souza

Publikováno v: European journal of medicinal chemistry. 151

In the search for new antifungal agents, a novel series of fifteen hydrazine-thiazole derivatives was synthesized and assayed in vitro against six clinically important Candida and Cryptococcus species and Paracoccidioides brasiliensis. Eight compound

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e6d857212ba0ee220c989ffafe2061
https://pubmed.ncbi.nlm.nih.gov/29626797

Effects of two 6-quinolinyl chalcones on the integrity of plasma membrane of Paracoccidioides brasiliensis

Autor: Patrícia Silva Cisalpino, Beatriz M. Borelli, Luciana de Carvalho Tavares, Gabriele de Matos Cardoso Perdigão, Carlos A. Rosa, Susana Johann, Nívea Pereira de Sá, Moacir Geraldo Pizzolatti, Elaine M. Souza-Fagundes, Paulo Js Barbeira, Leandro Espíndola

Publikováno v: The Journal of antibiotics. 70(3)

Paracoccidioidomycosis is the most prevalent systemic mycosis in Latin America, yet few therapeutic options exist. Our aim was to search for new compounds with high efficacy, low toxicity, shorter treatment time and affordable cost. We studied two sy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861ead546818ce2653436e2a0d5db826
https://pubmed.ncbi.nlm.nih.gov/28074055