Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Beatriz Lorente-Canovas"'
Autor:
Andrew P. Cope, David Scott, Fowzia Ibrahim, Caroline J Doré, James Galloway, Margaret H. Y. Ma, David Walker, Ira Pande, Beatriz Lorente-Canovas, Ailsa Bosworth
Publikováno v:
Ibrahim, F, Lorente-Cánovas, B, Doré, C J, Bosworth, A, Ma, M H, Galloway, J B, Cope, A P, Pande, I, Walker, D & Scott, D L 2017, ' Optimizing treatment with tumour necrosis factor inhibitors in rheumatoid arthritis-a proof of principle and exploratory trial : is dose tapering practical in good responders? ', Rheumatology (Oxford, England), vol. 56, no. 11, pp. 2004-2014 . https://doi.org/10.1093/rheumatology/kex315
Rheumatology (Oxford, England)
Rheumatology (Oxford, England)
Objectives: RA patients receiving TNF inhibitors (TNFi) usually maintain their initial doses. The aim of the Optimizing Treatment with Tumour Necrosis Factor Inhibitors in Rheumatoid Arthritis trial was to evaluate whether tapering TNFi doses causes
Autor:
Beatriz Lorente-Canovas, Rubén Corral-San-Miguel, Matías Hidalgo-Sánchez, José Luis Ferran, Faustino Marín, Pilar Aroca, Luis Puelles
Publikováno v:
Developmental Biology. 361:12-26
The interpeduncular nucleus (IP) is a key limbic structure, highly conserved evolutionarily among vertebrates. The IP receives indirect input from limbic areas of the telencephalon, relayed by the habenula via the fasciculus retroflexus. The function
Autor:
Caroline J. Doré, Fowzia Ibrahim, Gabrielle H. Kingsley, David Walker, David Scott, Ira Pande, James B Galloway, David G. I. Scott, Andrew Cope, M. H. Ma, Beatriz Lorente-Canovas
Publikováno v:
Rheumatology.
Publikováno v:
The Journal of Comparative Neurology. 496:802-818
We investigated in the mouse and chick the neuroepithelial origin and development of the locus coeruleus (LoC), the most important noradrenergic neuronal population in the brain. We first studied the topography of the developing LoC in the hindbrain,
Autor:
Margaret H. Y. Ma, Andrew P. Cope, Gabrielle Kingsley, Fowzia Ibrahim, Beatriz Lorente-Canovas, David Scott, James Galloway
Publikováno v:
Annals of the Rheumatic Diseases. 74:706.1-706
Background Treating rheumatoid arthritis (RA) with tumour necrosis factor inhibitors (TNFi) involves inducing then maintaining responses. Currently both use identical TNFi dosing regimens. Objectives OPTTIRA, a pragmatic, multicentre, 12-month random
Autor:
Beatriz Lorente-Cánovas, Stephanie Eckrich, Morag A Lewis, Stuart L Johnson, Walter Marcotti, Karen P Steel
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0261530 (2022)
Tasmanian devil (tde) mice are deaf and exhibit circling behaviour. Sensory hair cells of mutants show disorganised hair bundles with abnormally thin stereocilia. The origin of this mutation is the insertion of a transgene which disrupts expression o
Externí odkaz:
https://doaj.org/article/cee86f7ee77649caa32fec15c001cbb2
Autor:
Rubén Corral-San Miguel, Beatriz Lorente-Canovas, Faustino Marín, Luis Puelles, José Luis Ferran, Pilar Aroca
Publikováno v:
Mechanisms of Development. 126:S306
Autor:
Beatriz Lorente-Cánovas, Neil Ingham, Elizabeth E. Norgett, Zoe J. Golder, Fiona E. Karet Frankl, Karen P. Steel
Publikováno v:
Disease Models & Mechanisms, Vol 6, Iss 2, Pp 434-442 (2013)
SUMMARY Mutations in the ATP6V0A4 gene lead to autosomal recessive distal renal tubular acidosis in patients, who often show sensorineural hearing impairment. A first Atp6v0a4 knockout mouse model that recapitulates the loss of H+-ATPase function see
Externí odkaz:
https://doaj.org/article/bcf66fb288e749b4b8814bf0f935000e
Autor:
Giorgia Girotto, Dragana Vuckovic, Annalisa Buniello, Beatriz Lorente-Cánovas, Morag Lewis, Paolo Gasparini, Karen P Steel
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85352 (2014)
Considerable progress has been made in identifying deafness genes, but still little is known about the genetic basis of normal variation in hearing function. We recently carried out a Genome Wide Association Study (GWAS) of quantitative hearing trait
Externí odkaz:
https://doaj.org/article/b7b877d8f59f463eb3a77d6d10a2dff6
Autor:
Georg Steffes, Beatriz Lorente-Cánovas, Selina Pearson, Rachael H Brooker, Sarah Spiden, Amy E Kiernan, Jean-Louis Guénet, Karen P Steel
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e51065 (2012)
Mutanlallemand (mtl) and Belly Spot and Deafness (bsd) are two new spontaneous alleles of the Lmx1a gene in mice. Homozygous mutants show head tossing and circling behaviour, indicative of vestibular defects, and they have short tails and white belly
Externí odkaz:
https://doaj.org/article/463643acdb0c45af869718d1e1c8efc9