Výsledky vyhledávání - "Beatriz Hernández-Novoa"

Akademický článek

Potential healthcare resource use and associated costs of every 2 month injectable cabotegravir plus rilpivirine long-acting regimen implementation in the Spanish National Healthcare System compared to daily oral HIV treatments

Autor: Laura-Amanda Vallejo Aparicio, Victoria Neches García, Beatriz Hernández-Novoa, Gregorio Casado, Ferrán Jodar, Marco Pinel, Daniel Callejo Velasco

Publikováno v: BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-9 (2024)

Abstract Introduction HIV treatment currently consists of daily oral antiretroviral therapy (ART). Cabotegravir + rilpivirine long-acting (CAB + RPV LA) is the first ART available in Spain administered every 2 months through intramuscular injection b

Externí odkaz: https://doaj.org/article/bbed26e2cce74f478f2a9a4614a0aee3

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Akademický článek

Prolonged administration of maraviroc reactivates latent HIV in vivo but it does not prevent antiretroviral-free viral rebound

Autor: María Rosa López-Huertas, Carolina Gutiérrez, Nadia Madrid-Elena, Beatriz Hernández-Novoa, Julián Olalla-Sierra, Montserrat Plana, Rafael Delgado, Rafael Rubio, María Ángeles Muñoz-Fernández, Santiago Moreno

Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)

Abstract Human immunodeficiency virus (HIV) remains incurable due to latent viral reservoirs established in non-activated CD4 T cells that cannot be eliminated via antiretroviral therapy. Current efforts to cure HIV are focused on identifying drugs t

Externí odkaz: https://doaj.org/article/d1d63f1fdd2b4f53a1ec286acb22c2ef

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Contribution of cabotegravir + rilpivirine long-acting for the treatment of HIV-1 infection

Autor: Miguel Ángel, Calleja-Hernández, José Manuel, Martinez-Sesmero, Laura Amanda, Vallejo-Aparicio, Beatriz, Hernández-Novoa, Xavier, Badia

Publikováno v: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria. 46(4)

To determine the value contribution of cabotegravir + rilpivirine, the first injectable every two months long-acting antiretroviral regimen, using multi-criteria decision analysis.The study was developed in two phases. After a small pilot, a field or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0def1f77bd928c797f1392296bc64d5e
https://pubmed.ncbi.nlm.nih.gov/36183218

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Akademický článek

Screening for precancerous anal lesions with P16/Ki67 immunostaining in HIV-infected MSM.

Autor: Sergio Serrano-Villar, Beatriz Hernández-Novoa, Amparo de Benito, Jorge Del Romero, Antonio Ocampo, José Ramón Blanco, Mar Masiá, Elena Sendagorta, Gonzalo Sanz, Santiago Moreno, José A Pérez-Molina

Publikováno v: PLoS ONE, Vol 12, Iss 11, p e0188851 (2017)

Screening of anal cancer in HIV-infected MSM with anal cytology results in high rates of false positive results and elevated burden of high-resolution anoscopies. High-risk HPV up-regulates p16 and Ki67 expression in epithelial cells. We assessed the

Externí odkaz: https://doaj.org/article/8c8d1416e73c4e90b2d62d89fce577d6

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Prolonged administration of maraviroc reactivates latent HIV in vivo but it does not prevent antiretroviral-free viral rebound

Autor: Rafael Coll Delgado, Santiago Moreno, Carolina Gutierrez, Julián Olalla-Sierra, María Rosa López-Huertas, Rafael M. Rubio, Nadia Madrid-Elena, María Ángeles Muñoz-Fernández, Beatriz Hernández-Novoa, Montserrat Plana

Publikováno v: Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)

Human immunodeficiency virus (HIV) remains incurable due to latent viral reservoirs established in non-activated CD4 T cells that cannot be eliminated via antiretroviral therapy. Current efforts to cure HIV are focused on identifying drugs that will

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::460047c40e92b2cab7eb7194b9a199a2
http://europepmc.org/articles/PMC7749169

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Akademický článek

Intensification of antiretroviral therapy with a CCR5 antagonist in patients with chronic HIV-1 infection: effect on T cells latently infected.

Autor: Carolina Gutiérrez, Laura Díaz, Alejandro Vallejo, Beatriz Hernández-Novoa, María Abad, Nadia Madrid, Viktor Dahl, Rafael Rubio, Ana M Moreno, Fernando Dronda, José Luis Casado, Enrique Navas, María Jesús Pérez-Elías, Javier Zamora, Sarah Palmer, Eduardo Muñoz, María Ángeles Muñoz-Fernández, Santiago Moreno

Publikováno v: PLoS ONE, Vol 6, Iss 12, p e27864 (2011)

The primary objective was to assess the effect of MVC intensification on latently infected CD4(+) T cells in chronically HIV-1-infected patients receiving antiretroviral therapy.We performed an open-label pilot phase II clinical trial involving chron

Externí odkaz: https://doaj.org/article/7e06c4df50d74c84b731c758328cd223

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Deep-Sequencing Analysis of the Dynamics of HIV-1 Quasiespecies in Naive Patients during a Short Exposure to Maraviroc

Autor: Alberto Rastrojo, José Alcamí, Mayte Pérez-Olmeda, Francisco Díez-Fuertes, Almudena Cascajero, Beatriz Hernández-Novoa, Begoña Aguado, Santiago Moreno

Publikováno v: Repisalud
Instituto de Salud Carlos III (ISCIII)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

In this study, we have characterized quasispecies dynamics and the evolution of viral tropism in naive HIV-1-infected patients treated with a short course of maraviroc monotherapy (ClinicalTrials.gov registration no. NCT01060618) independently of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ea93be80b64fa1436a4b94a7e593ba5
https://europepmc.org/articles/PMC5952159/

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Maraviroc Is Associated with Latent HIV-1 Reactivation through NF-κB Activation in Resting CD4+ T Cells from HIV-Infected Individuals on Suppressive Antiretroviral Therapy

Autor: María Laura García-Bermejo, María Coronel Díaz, Beatriz Hernández-Novoa, Alberto Diaz de Santiago, María Rosa López-Huertas, Carolina Gutiérrez, Nadia Madrid-Elena, Fernando Dronda, Ester Dominguez, Sergio Serrano-Villar, Santiago Moreno, Beatriz Sastre

Publikováno v: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

Maraviroc is a CCR5 antagonist used in the treatment of HIV-1 infection. We and others have suggested that maraviroc could reactivate latent HIV-1. To test the latency-reversing potential of maraviroc and the mechanisms involved, we performed a phase

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca17180d19dc54cb0c1c33a63019e1c
https://europepmc.org/articles/PMC5899181/

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Expression of gut-homing β7 receptor on T cells: surrogate marker for microbial translocation in suppressed HIV-1-infected patients?

Autor: María Ángeles Muñoz-Fernández, María Abad-Fernández, Sacramento Moreno, L. E. Díaz, Antonio Vallejo, C Gutiérrez, Nadia Madrid, Beatriz Hernández-Novoa

Publikováno v: HIV Medicine. 16:15-23

Objectives In view of the fact that mucosal damage associated with HIV-1 infection leads to microbial translocation despite successful antiretroviral treatment, we analysed microbial translocation and expression of the gut-homing β7 receptor on peri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a18dda4d85e771ee61726da85f5c3d6f
https://doi.org/10.1111/hiv.12167

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