Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Beatriz Garcia-Pelaez"'
Autor:
Jaume Roca-Arias, Jordi Bertran-Alamillo, Ruth Román, Cristina Aguado, Laura López, Leticia Ferro-Leal, Beatriz Garcia-Pelaez, Rodrigo de Oliveira Cavagna, Silvia Teixeira, Rafael Rosell, Rui Manuel Reis, Miguel A. Molina-Vila, Ivana Sullivan
Publikováno v:
Cancer Research. 83:4039-4039
Background: RET (rearranged during transfection) is a proto-oncogene encoding for a tyrosine kinase membrane receptor that promotes protein synthesis and cell proliferation. A small percentage of human tumors harbor RET fusions or mutations as oncoge
Autor:
Silvia García-Roman, Mónica Garzón-Ibáñez, Jordi Bertrán-Alamillo, Núria Jordana-Ariza, Ana Giménez-Capitán, Beatriz García-Peláez, Marta Vives-Usano, Jordi Codony-Servat, Erik d'Hondt, Rafael Rosell, Miguel Ángel Molina-Vila
Publikováno v:
Translational Oncology, Vol 40, Iss , Pp 101878- (2024)
Background: The EGFR pathway is involved in intrinsic and acquired resistance to a wide variety of targeted therapies in cancer. Vaccination represents an alternative to the administration of anti-EGFR monoclonal antibodies, such as cetuximab or pani
Externí odkaz:
https://doaj.org/article/fc3b1c5adf764070ae7e5f5cd5f1ee1a
Autor:
Montse Verdú, Natalia Rodon, Miquel Calvo, Xavier Puig, Beatriz Garcia-Pelaez, Isabel Trias, Olga Díaz, Carme Pubill, Ruth Román
Publikováno v:
Revista Española de Patología. 49:226-233
The study of epidermal growth factor receptor mutations has become essential for the treatment of lung cancer. The aim of this study was to find a correlation between morphological changes and EGFR mutational status using both immunohistochemistry an
Autor:
Miguel Angel Molina Vila, Andrés Aguilar, Alejandro Martínez Bueno, Rafael Rosell Costa, Jordi Bertran Alamillo, Maria Gonzalez Cao, Mónica Garzón, Nuria Jordana Ariza, Erika Aldeguer, Clara Mayo de las Casas, Beatriz Garcia-Pelaez, Ruth Román, Silvia Garcia-Roman, Santiago Viteri, Sonia Rodríguez
Publikováno v:
Cancer Research. 80:3175-3175
Background: Somatic copy number gains (CNGs; i.e. amplifications) have been related to tumorogenesis and some of them are designated targets for therapies, such as HER2 amplification in breast cancer. In the case of NSCLC, MET alterations are receivi
Autor:
Ruth Román-Lladó, Cristina Aguado, Núria Jordana-Ariza, Jaume Roca-Arias, Sonia Rodríguez, Erika Aldeguer, Mónica Garzón-Ibañez, Beatriz García-Peláez, Marta Vives-Usano, Ana Giménez-Capitán, Andrés Aguilar, Alejandro Martinez-Bueno, María Gonzalez Cao, Florencia García-Casabal, Santiago Viteri, Clara Mayo de las Casas, Rafael Rosell, Miguel Angel Molina-Vila
Publikováno v:
Journal of Molecular Pathology, Vol 4, Iss 1, Pp 57-68 (2023)
Genetic and drug sensitivity assays on primary cultures are not only of basic but also of translational interest and could eventually aid oncologists in the selection of treatments. However, cancer cells need to be identified and differentiated from
Externí odkaz:
https://doaj.org/article/4aa6f599da1a468abb18119b19ad755f
Autor:
Beatriz Garcia-Pelaez, Xavier Puig, Olga Díaz, Montse Verdú, Ruth Román, Carme Pubill, Natalia Rodon
Publikováno v:
Revista Española de Patología. 48:67-74
Resumen El estudio del ganglio centinela es una parte esencial de la estadificacion en cancer de mama. El One-Step Nucleic Acid Amplification (OSNA) es un ensayo molecular intraoperatorio que mide la cantidad de ARNm de citoqueratina 19 (CK19) presen
Autor:
Gloria Biern, Miquel Calvo, Natalia Rodon, Xavier Puig, Beatriz Garcia-Pelaez, Teresa González Serrano, Ruth Román, Montse Verdú, Olga Díaz
Publikováno v:
Revista Española de Patología. 48:2-8
Determining microsatellite instability status (MSI) is now highly recommended for all diagnosed colorectal carcinomas, both as a first approach to identify putative Lynch syndrome patients, and as a valuable prognostic indicator as it is associated w
Autor:
Ruth Román, Begonya Martinez, Natalia Rodon, Beatriz Garcia-Pelaez, Isabel Trias, Teresa González Serrano, Carme Pubill, Nuria Arraiza, Xavier Puig, Montse Verdú
Publikováno v:
Applied immunohistochemistrymolecular morphology : AIMM. 23(8)
The coexpression of HER2 and EGFR L858R in a solitary nodule removed from the lung, whose mutation was not confirmed by molecular techniques, made us think about the possible existence of a cross-reaction between HER2 and the EGFR L858R-specific anti
Autor:
Montse Verdú, Miquel Calvo, Natalia Rodon, Xavier Puig, Ruth Román, Beatriz Garcia-Pelaez, Josep M. Banus, Arturo Domínguez, Isabel Trias
Publikováno v:
Virchows Archiv : an international journal of pathology. 462(6)
ERG gene rearrangement has been identified as a highly specific alteration that is present in 40-50 % of prostate carcinomas. The standardization of an immunohis- tochemical assay with a novel anti-ERG antibody recently described would have significa
Autor:
Atocha Romero, Eloisa Jantus‐Lewintre, Beatriz García‐Peláez, Ana Royuela, Amelia Insa, Patricia Cruz, Ana Collazo, Javier Pérez Altozano, Oscar Juan Vidal, Pilar Diz, Manuel Cobo, Berta Hernández, Sergio Vázquez Estevez, Gretel Benítez, Maria Guirado, Margarita Majem, Reyes Bernabé, Ana Laura Ortega, Ana Blasco, Joaquim Bosch‐Barrera, Jose M. Jurado, Jorge García González, Santiago Viteri, Carlos Garcia Giron, Bartomeu Massutí, Ana Lopez Martín, Alejandro Rodriguez‐Festa, Silvia Calabuig‐Fariñas, Miguel Ángel Molina‐Vila, Mariano Provencio
Publikováno v:
Molecular Oncology, Vol 15, Iss 1, Pp 43-56 (2021)
Several platforms for noninvasive EGFR testing are currently used in the clinical setting with sensitivities ranging from 30% to 100%. Prospective studies evaluating agreement and sources for discordant results remain lacking. Herein, seven methodolo
Externí odkaz:
https://doaj.org/article/fee84be40c92476693b579001138154a