Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Beatriz Garat"'
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Trypanosoma cruzi is a digenetic unicellular parasite that alternates between a blood-sucking insect and a mammalian, host causing Chagas disease or American trypanosomiasis. In the insect gut, the parasite differentiates from the non-replicative try
Externí odkaz:
https://doaj.org/article/2fba4634957c4806a24d9737c7a9ded3
Autor:
Juan Manuel Trinidad-Barnech, Rafael Sebastián Fort, Guillermo Trinidad Barnech, Beatriz Garat, María Ana Duhagon
Publikováno v:
Non-Coding RNA, Vol 9, Iss 1, p 15 (2023)
MicroRNAs are small RNAs that regulate gene expression through complementary base pairing with their target mRNAs. A substantial understanding of microRNA target recognition and repression mechanisms has been reached using diverse empirical and bioin
Externí odkaz:
https://doaj.org/article/01094e5270874c5ba9cd3d93b341a6ae
Autor:
Santiago Chávez, Michael D. Urbaniak, Corinna Benz, Pablo Smircich, Beatriz Garat, José R. Sotelo-Silveira, María Ana Duhagon
Publikováno v:
mSphere, Vol 6, Iss 5 (2021)
Trypanosoma cruzi
Externí odkaz:
https://doaj.org/article/74a3a3ff7d864eb198d92c6fefb8aec8
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
It is generally accepted that the presence of ORFs in the 5′ untranslated region of eukaryotic transcripts modulates the production of proteins by controlling the translation initiation rate of the main CDS. In trypanosomatid parasites, which almos
Externí odkaz:
https://doaj.org/article/9678490620eb41d0a34dd720b6d77f61
Autor:
M. Florencia Mosquillo, Pablo Smircich, Analía Lima, Sergio A. Gehrke, Gonzalo Scalese, Ignacio Machado, Dinorah Gambino, Beatriz Garat, Leticia Pérez-Díaz
Publikováno v:
Bioinorganic Chemistry and Applications, Vol 2020 (2020)
Treatment for Chagas disease, a parasitosis caused by Trypanosoma cruzi, has always been based on two drugs, nifurtimox and benznidazole, despite the toxic side effects described after prolonged prescription. In this work, we study a new prospective
Externí odkaz:
https://doaj.org/article/3b3f6848583b4f748ee4976a8fbf20e2
Autor:
Carolina Oliveira-Rizzo, María Carolina Ottati, Rafael Sebastián Fort, Santiago Chavez, Juan Manuel Trinidad, Andrés DiPaolo, Beatriz Garat, José Roberto Sotelo-Silveira, María Ana Duhagon
Publikováno v:
Non-Coding RNA, Vol 8, Iss 1, p 11 (2022)
Prostate cancer is a major health problem worldwide. MiR-183 is an oncomiR and a candidate biomarker in prostate cancer, affecting various pathways responsible for disease initiation and progression. We sought to discover the most relevant processes
Externí odkaz:
https://doaj.org/article/e2af15bcb6e4493ab61ba8b74f9dd0c1
Autor:
Rafael Sebastián Fort, Cecilia Mathó, Carolina Oliveira-Rizzo, Beatriz Garat, José Roberto Sotelo-Silveira, María Ana Duhagon
Publikováno v:
Experimental Hematology & Oncology, Vol 7, Iss 1, Pp 1-14 (2018)
Abstract Prostate cancer is a major health problem worldwide due to its high incidence morbidity and mortality. There is currently a need of improved biomarkers, capable to distinguish mild versus aggressive forms of the disease, and thus guide thera
Externí odkaz:
https://doaj.org/article/3d0a80e885f3416e8f89f37b88e02985
Autor:
Rafael Sebastián Fort, Cecilia Mathó, Murilo Vieira Geraldo, María Carolina Ottati, Alex Shimura Yamashita, Kelly Cristina Saito, Katia Ramos Moreira Leite, Manuel Méndez, Noemí Maedo, Laura Méndez, Beatriz Garat, Edna Teruko Kimura, José Roberto Sotelo-Silveira, María Ana Duhagon
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-13 (2018)
Abstract Background Nc886 is a 102 bp non-coding RNA transcript initially classified as a microRNA precursor (Pre-miR-886), later as a divergent homologue of the vault RNAs (vtRNA 2–1) and more recently as a novel type of RNA (nc886). Although nc88
Externí odkaz:
https://doaj.org/article/bee1129aa057406aab9a20d1c9b24fab
Publikováno v:
BMC Research Notes, Vol 10, Iss 1, Pp 1-7 (2017)
Abstract Background Trypanosoma cruzi and Trypanosoma brucei are protozoan parasites causing Chagas disease and African sleeping sickness, displaying unique features of cellular and molecular biology. Remarkably, no canonical signals for RNA polymera
Externí odkaz:
https://doaj.org/article/ab48f46f56d74543bcaa9b8eb3c6d0e1
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215160 (2019)
Trypanosoma cruzi, the protozoan parasite that causes Chagas' disease, exhibits peculiar biological features. Among them, the presence of a unique mitochondrion is remarkable. Even though the mitochondrial DNA constitutes up to 25% of total cellular
Externí odkaz:
https://doaj.org/article/f9aaf02f74a946c4b99b6277fca1cbdb