Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Beatriz G. Perez-Nievas"'
Autor:
Beatriz G. Perez-Nievas, Louisa Johnson, Paula Beltran-Lobo, Martina M. Hughes, Luciana Gammallieri, Francesca Tarsitano, Monika A. Myszczynska, Irina Vazquez-Villasenor, Maria Jimenez-Sanchez, Claire Troakes, Stephen B. Wharton, Laura Ferraiuolo, Wendy Noble
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-17 (2021)
Abstract Background Pathological interactions between β-amyloid (Aβ) and tau drive synapse loss and cognitive decline in Alzheimer’s disease (AD). Reactive astrocytes, displaying altered functions, are also a prominent feature of AD brain. This l
Externí odkaz:
https://doaj.org/article/d262341bcc2d4dd5ae59b2b8156cdf4d
Autor:
Isabel Barroeta-Espar, Laura D. Weinstock, Beatriz G. Perez-Nievas, Avery C. Meltzer, Michael Siao Tick Chong, Ana C. Amaral, Melissa E. Murray, Krista L. Moulder, John C. Morris, Nigel J. Cairns, Joseph E. Parisi, Val J. Lowe, Ronald C. Petersen, Julia Kofler, Milos D. Ikonomovic, Oscar López, William E. Klunk, Richard P. Mayeux, Matthew P. Frosch, Levi B. Wood, Teresa Gomez-Isla
Publikováno v:
Neurobiology of Disease, Vol 121, Iss , Pp 327-337 (2019)
Our group has previously studied the brains of some unique individuals who are able to tolerate robust amounts of Alzheimer's pathological lesions (amyloid plaques and neurofibrillary tangles) without experiencing dementia while alive. These rare res
Externí odkaz:
https://doaj.org/article/fb448af25f8c45e29b685fb3b437ea3f
Autor:
Ana Claudia Amaral, Beatriz G. Perez-Nievas, Michael Siao Tick Chong, Alicia Gonzalez-Martinez, Herminia Argente-Escrig, Sara Rubio-Guerra, Caitlin Commins, Serra Muftu, Bahareh Eftekharzadeh, Eloise Hudry, Zhanyun Fan, Prianca Ramanan, Shuko Takeda, Matthew P. Frosch, Susanne Wegmann, Teresa Gomez-Isla
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102058- (2021)
Summary: It has been suggested that aberrant activation of glycogen synthase kinase-3-beta (GSK-3β) can trigger abnormal tau hyperphosphorylation and aggregation, which ultimately leads to neuronal/synaptic damage and impaired cognition in Alzheimer
Externí odkaz:
https://doaj.org/article/0834daf1f0d14cb1bd40b2f5ea69e654
Publikováno v:
Frontiers in Aging Neuroscience, Vol 10 (2018)
Reactive astrocytes were identified as a component of senile amyloid plaques in the cortex of Alzheimer’s disease (AD) patients several decades ago. However, their role in AD pathophysiology has remained elusive ever since, in part owing to the ext
Externí odkaz:
https://doaj.org/article/0ed776228c5c4828a6e85c6b58f20788
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd1a0f028e6a06018794c469d2952b40
https://doi.org/10.1002/alz.061325
https://doi.org/10.1002/alz.061325
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbc7ee56ebc1086c5831414cb4a949ef
https://doi.org/10.1002/alz.062245
https://doi.org/10.1002/alz.062245
Autor:
Paula Beltran-Lobo, Matthew J. Reid, Maria Jimenez-Sanchez, Alexei Verkhratsky, Beatriz G. Perez-Nievas, Wendy Noble
Publikováno v:
King's College London
Astrocytes are key homeostatic and defensive cells of the central nervous system (CNS). They undertake numerous functions during development and in adulthood to support and protect the brain through finely regulated communication with other cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c297f366ff79df6f091e0158c29cd164
https://pubmed.ncbi.nlm.nih.gov/36449279
https://pubmed.ncbi.nlm.nih.gov/36449279
Autor:
Markus P. Kummer, Juan C. Leza, Dick Terwel, Beatriz G. Perez Nievas, Michael T. Heneka, Thea Hammerschmidt
Publikováno v:
Journal of Neurochemistry. 116:43-52
Both hypercortisolemia and hippocampal damage are features found in patients diagnosed of Alzheimer's disease (AD) and epidemiological evidence supports a role for stress as a risk factor for AD. It is known that immobilization stress is followed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55cc5d68c43894436bc1ff6d9ea684d6
https://doi.org/10.1111/j.1471-4159.2010.07083.x
https://doi.org/10.1111/j.1471-4159.2010.07083.x
Autor:
Borja García-Bueno, Juan C. Leza, Beatriz G. Perez Nievas, José L. M. Madrigal, Jorge Manzanares, Silvia Zoppi
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
14 p., 9 figures and references.
Exposure to stress elicits excitoxicity and neuroinflammation in the brain, contributing to cell death and damage in stress-related neurological and neuropsychiatric diseases. The endocannabinoid system is presen
Exposure to stress elicits excitoxicity and neuroinflammation in the brain, contributing to cell death and damage in stress-related neurological and neuropsychiatric diseases. The endocannabinoid system is presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::753527e772be9f440ef6f29a25526fc5
http://hdl.handle.net/10261/55078
http://hdl.handle.net/10261/55078
Autor:
Beatriz G, Perez Nievas, Thea, Hammerschmidt, Markus P, Kummer, Dick, Terwel, Juan C, Leza, Michael T, Heneka
Publikováno v:
Journal of neurochemistry. 116(1)
Both hypercortisolemia and hippocampal damage are features found in patients diagnosed of Alzheimer's disease (AD) and epidemiological evidence supports a role for stress as a risk factor for AD. It is known that immobilization stress is followed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c951e2416babdff4b77f8bab3f665dba
https://pubmed.ncbi.nlm.nih.gov/21044080
https://pubmed.ncbi.nlm.nih.gov/21044080