Devices for Prevention of Atrial Tachyarrhythmias

Autor: Ignacio Fernández Lozano, Jorge Toquero, José Antonio Fernández Díaz, Bogdan Ionescu, Vanesa Moñivas, Pilar Ortiz, Beatriz Fuertes, Luis Alonso Pulpón

Publikováno v: Indian Pacing and Electrophysiology Journal, Vol 4, Iss 2, Pp 50-62 (2004)

Atrial fibrillation (AF) is the most frequent sustained cardiac arrhythmia in clinical practice and, although its importance has been underestimated even in recent years, we are now becoming aware of its clinical transcendence1,2,3. The classical tre

Externí odkaz: https://doaj.org/article/bf2726f6b9a54defac70903d6fa1988c

Editorial: Tumor microenvironment immunophenotypes and disease progression

Autor: Ana Carolina Monteiro, Ana Paula Lepique, Martin Bonamino, Mercedes Beatriz Fuertes

Publikováno v: Frontiers in Immunology, Vol 14 (2023)

Externí odkaz: https://doaj.org/article/34a106eed0c04ae1b97ddbab1601d25a

Leveraging NKG2D Ligands in Immuno-Oncology

Autor: Mercedes Beatriz Fuertes, Carolina Inés Domaica, Norberto Walter Zwirner

Publikováno v: Frontiers in Immunology, Vol 12 (2021)

Immune checkpoint inhibitors (ICI) revolutionized the field of immuno-oncology and opened new avenues towards the development of novel assets to achieve durable immune control of cancer. Yet, the presence of tumor immune evasion mechanisms represents

Externí odkaz: https://doaj.org/article/c7860ee9993b46979039907b880c1422

Restoration of antitumor immunity through anti-MICA antibodies elicited with a chimeric protein

Autor: Kenneth W Hance, Nicolas Torres, María Victoria Regge, Florencia Secchiari, Adrián David Friedrich, Raúl Germán Spallanzani, Ximena Lucía Raffo Iraolagoitia, Sol Yanel Núñez, Jessica Mariel Sierra, Andrea Ziblat, María Cecilia Santilli, Nicolás Gilio, Evangelina Almada, Constanza Lauche, Romina Pardo, Carolina Inés Domaica, Mercedes Beatriz Fuertes, Kevin Patrick Madauss, Israel S Gloger, Vanesa Zylberman, Fernando Alberto Goldbaum, Norberto Walter Zwirner

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)

Background Natural killer and cytotoxic CD8+ T cells are major players during antitumor immunity. They express NKG2D, an activating receptor that promotes tumor elimination through recognition of the MHC class I chain-related proteins A and B (MICA a

Externí odkaz: https://doaj.org/article/60794d6d6f5348769085d3ffeeb174f9

Tumor-Experienced Human NK Cells Express High Levels of PD-L1 and Inhibit CD8+ T Cell Proliferation

Autor: Aldana Trotta, Andrea Ziblat, Gonzalo Vitagliano, Mercedes Beatriz Fuertes, M. Cecilia Santilli, Adrián Friedrich, Carolina Ines Domaica, Carlos Ameri, Mariana Gantov, Hernando Rios Pita, Luis Rico, Sol Yanel Nuñez, Nicolás Richards, Agustin Rovegno, Jessica Mariel Sierra, María Victoria Regge, Florencia Secchiari, Ximena Lucía Raffo Iraolagoitia, Norberto Walter Zwirner, Nicolás Torres

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Frontiers in Immunology, Vol 12 (2021)

Natural Killer (NK) cells play a key role in cancer immunosurveillance. However, NK cells from cancer patients display an altered phenotype and impaired effector functions. In addition, evidence of a regulatory role for NK cells is emerging in divers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8860c35d8ade243f41c695f97f09659
https://doi.org/10.3389/fimmu.2021.745939