Redox RegulationviaGlutaredoxin-1 and ProteinS-Glutathionylation

Autor: Reiko Matsui, Beatriz Ferrán, Albin Oh, Di Shao, Dominique Croteau, Markus Bachschmid, Jingyan Han, David R. Pimentel

Publikováno v: Antioxidants & Redox Signaling. 32:677-700

Significance: Over the past several years, oxidative post-translational modifications of protein cysteines have been recognized for their critical roles in physiology and pathophysiology. Cells have harnessed thiol modifications involving both oxidat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::862cfc2c221dbcf7802f7a90e3f3335a
https://doi.org/10.1089/ars.2019.7963

Production of adeno-associated virus vectors for in vitro and in vivo applications

Autor: Toyokazu Kimura, Reiko Matsui, Takeshi Adachi, Yasuo Ido, Yuko Tsukahara, Markus Bachschmid, David R. Pimentel, Beatriz Ferrán, Ivan Luptak, Qifan Shang, Suveer Desai, Alessandra Fedoce

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports

Delivering and expressing a gene of interest in cells or living animals has become a pivotal technique in biomedical research and gene therapy. Among viral delivery systems, adeno-associated viruses (AAVs) are relatively safe and demonstrate high gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497dbd16e504a28c679fac487f931e71
http://link.springer.com/article/10.1038/s41598-019-49624-w

Soluble pathogenic tau enters brain vascular endothelial cells and drives cellular senescence and brain microvascular dysfunction in a mouse model of tauopathy

Autor: Stacy A. Hussong, Andy Q. Banh, Candice E. Van Skike, Angela O. Dorigatti, Stephen F. Hernandez, Matthew J. Hart, Beatriz Ferran, Haneen Makhlouf, Maria Gaczynska, Pawel A. Osmulski, Salome A. McAllen, Kelly T. Dineley, Zoltan Ungvari, Viviana I. Perez, Rakez Kayed, Veronica Galvan

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)

Abstract Vascular mechanisms of Alzheimer’s disease (AD) may constitute a therapeutically addressable biological pathway underlying dementia. We previously demonstrated that soluble pathogenic forms of tau (tau oligomers) accumulate in brain microv

Externí odkaz: https://doaj.org/article/a5155c1e3b244cd383da055394ad656e

Over-expression of Neuron-derived Orphan Receptor-1 (NOR-1) exacerbates neointimal hyperplasia after vascular injury

Autor: J. A. Alonso, Anna Guadall, José Martínez-González, María A. Navarro, Cristina Rodríguez, Jesús Osada, Alicia de Diego, Ricardo Rodríguez-Calvo, Pedro Muniesa, Olivier Calvayrac, Beatriz Ferrán

Publikováno v: Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2013, 22 (10), pp.1949-1959. ⟨10.1093/hmg/ddt042⟩
HUMAN MOLECULAR GENETICS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname

International audience; We have previously shown that NOR-1 (NR4A3) modulates the proliferation and survival of vascular cells in culture. However, in genetically modified animal models, somewhat conflicting results have been reported concerning the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4099afe4d2b82f378fe5abc0e41ea3c8
https://doi.org/10.1093/hmg/ddt042

Expresión de las fimbrias Fim2 y Fim3 desde el plasmidio pMMB67 en cepas de Bordetella pertussis

Autor: Lourdes Proenza, Javier Campos, Beatriz Ferrán, Ernesto Marcos, Celso Pérez

Publikováno v: Revista CENIC. Ciencias Biológicas, Vol 41, Iss 1, Pp 61-66 (2010)

Bordetella pertussis, el agente etiológico de la tos ferina, produce dos tipos de fimbrias serológicamente diferentes, denominadas Fim2 y Fim3. Las fimbrias 2 y 3 están compuestas por una subunidad proteica mayoritaria Fim2, de 22,5 kDa y Fim3, de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doajarticles::3857bb1e3ff33552009aa76b73b2e6f4
http://www.redalyc.org/articulo.oa?id=181221644008