Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Beatriz Fernández-Varas"'
Autor:
Miren Lasaga, Paula Río, Amaia Vilas-Zornoza, Nuria Planell, Susana Navarro, Diego Alignani, Beatriz Fernández-Varas, Daniel Mouzo, Josune Zubicaray, Roser M. Pujol, Eileen Nicoletti, Jonathan D. Schwartz, Julián Sevilla, Marina Ainciburi, Asier Ullate-Agote, Jordi Surrallés, Rosario Perona, Leandro Sastre, Felipe Prosper, David Gomez-Cabrero, Juan A. Bueren
Publikováno v:
Haematologica, Vol 108, Iss 10 (2023)
Clinical trials have shown that lentiviral-mediated gene therapy can ameliorate bone marrow failure (BMF) in nonconditioned Fanconi anemia (FA) patients resulting from the proliferative advantage of corrected FA hematopoietic stem and progenitor cell
Externí odkaz:
https://doaj.org/article/d53a95898f024aef96171022924acc08
Autor:
Alicia Usategui, Cristina Municio, Elena G. Arias-Salgado, María Martín, Beatriz Fernández-Varas, Manuel J. Del Rey, Patricia Carreira, Antonio González, Gabriel Criado, Rosario Perona, José L. Pablos
Publikováno v:
Immunity & Ageing, Vol 19, Iss 1, Pp 1-9 (2022)
Abstract Background To investigate the role of cell senescence in systemic sclerosis (SSc), we analyzed telomere shortening (TS) in SSc patients and the effect of targeting DNA damage in the bleomycin model of skin fibrosis. Results Telomere length (
Externí odkaz:
https://doaj.org/article/c39d1f7ddcdd4e77af7df6790b4c5c07
Autor:
Carlos Carrascoso-Rubio, Hidde A. Zittersteijn, Laura Pintado-Berninches, Beatriz Fernández-Varas, M. Luz Lozano, Cristina Manguan-Garcia, Leandro Sastre, Juan A. Bueren, Rosario Perona, Guillermo Guenechea
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-8 (2021)
Abstract Dyskeratosis congenita (DC) is a rare telomere biology disorder, which results in different clinical manifestations, including severe bone marrow failure. To date, the only curative treatment for the bone marrow failure in DC patients is all
Externí odkaz:
https://doaj.org/article/3e9b4086c5e84d35a41e8439e2fd5480
Autor:
Marta Iglesias, Daniel A. Felix, Óscar Gutiérrez-Gutiérrez, Maria del Mar De Miguel-Bonet, Sounak Sahu, Beatriz Fernández-Varas, Rosario Perona, A. Aziz Aboobaker, Ignacio Flores, Cristina González-Estévez
Publikováno v:
Stem Cell Reports, Vol 13, Iss 2, Pp 405-418 (2019)
Summary: Reduction of caloric intake delays and prevents age-associated diseases and extends the life span in many organisms. It may be that these benefits are due to positive effects of caloric restriction on stem cell function. We use the planarian
Externí odkaz:
https://doaj.org/article/12104bd543f34db3a68faa6d3c7cc333
Autor:
Vanessa Rodríguez-Fanjul, Rosa Guerrero-López, Beatriz Fernández-Varas, Rosario Perona, Ana Sastre-Perona, Leandro Sastre
Publikováno v:
Cells, Vol 11, Iss 3, p 511 (2022)
Colorectal cancer is the second most common cancer in women, the third in men, and an important cause of cancer-related mortality. Recurrence and the development of chemotherapy resistance are major hindrances for patients’ treatment. The presence
Externí odkaz:
https://doaj.org/article/d9bdd852797a4f3db9bb7e8f00ef3370
Autor:
Verónica Moncho-Amor, Laura Pintado-Berninches, Inmaculada Ibañez de Cáceres, Ester Martín-Villar, Miguel Quintanilla, Probir Chakravarty, María Cortes-Sempere, Beatriz Fernández-Varas, Carlos Rodriguez-Antolín, Javier de Castro, Leandro Sastre, Rosario Perona
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 8, p 2036 (2019)
DUSP6/MKP3 is a dual-specific phosphatase that regulates extracellular regulated kinase ERK1/2 and ERK5 activity, with an increasingly recognized role as tumor suppressor. In silico studies from Gene expression Omnibus (GEO) and Cancer Genome atlas (
Externí odkaz:
https://doaj.org/article/fb059b0d7aee46c3a97b652aa3ff1004
Autor:
Miren Lasaga, Paula Río, Amaia Vilas-Zornoza, Nuria Planell, Susana Navarro, Diego Alignani, Beatriz Fernández-Varas, Josune Zubicaray, Roser M. Pujol, Eileen Nicoletti, Jonathan D. Schwartz, Julián Sevilla, Marina Ainciburi, Asier Ullate-Agote, Jordi Surrallés, Rosario Perona, Leandro Sastre, Felipe Prosper, David Gomez-Cabrero, Juan A. Bueren
SUMMARY PARAGRAPH Fanconi anemia (FA) is a monogenic inherited disease associated with mutations in genes that encode for proteins participating in the FA/BRCA DNA repair pathway. Mutations in FA genes result in chromosomal instability and cell death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0db0bf3349847b11087227da6bf0f549
https://doi.org/10.1101/2021.07.20.21260460
https://doi.org/10.1101/2021.07.20.21260460
Autor:
Óscar Gutiérrez-Gutiérrez, A. Aziz Aboobaker, Maria del Mar De Miguel-Bonet, Daniel A. Felix, Ignacio Flores, Cristina González-Estévez, Beatriz Fernández-Varas, Sounak Sahu, Rosario Perona, Marta Iglesias
Publikováno v:
Repisalud
Instituto de Salud Carlos III (ISCIII)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Stem Cell Reports, Vol 13, Iss 2, Pp 405-418 (2019)
Stem Cell Reports
Instituto de Salud Carlos III (ISCIII)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Stem Cell Reports, Vol 13, Iss 2, Pp 405-418 (2019)
Stem Cell Reports
Summary Reduction of caloric intake delays and prevents age-associated diseases and extends the life span in many organisms. It may be that these benefits are due to positive effects of caloric restriction on stem cell function. We use the planarian
Autor:
M. Luz Lozano, Juan A. Bueren, Hidde A. Zittersteijn, Guillermo Guenechea, Cristina Manguan-García, Carlos Carrascoso-Rubio, Leandro Sastre, Beatriz Fernández-Varas, Rosario Perona, Laura Pintado-Berninches
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-8 (2021)
instname
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-8 (2021)
© The Author(s).
Dyskeratosis congenita (DC) is a rare telomere biology disorder, which results in different clinical manifestations, including severe bone marrow failure. To date, the only curative treatment for the bone marrow failure in DC p
Dyskeratosis congenita (DC) is a rare telomere biology disorder, which results in different clinical manifestations, including severe bone marrow failure. To date, the only curative treatment for the bone marrow failure in DC p
Autor:
Lurdes Planas, Beatriz Fernández-Varas, Rosa Guerrero-López, Guillermo Guenechea, Rosario Perona, Elena G Arias-Salgado, Julio Cortijo, Leandro Sastre, Manoli Igartua, Susana P. Egusquiaguirre, Rosa Maria Hernandez, Laura Pintado-Berninches, Cristina Manguan-García, Ana Montes-Worboys, Laura Iarriccio, Maria Molina-Molina, José Luis Pedraz, Adela Serrano
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Addi. Archivo Digital para la Docencia y la Investigación
Dipòsit Digital de la UB
Universidad de Barcelona
instname
Addi: Archivo Digital para la Docencia y la Investigación
Universidad del País Vasco
Addi. Archivo Digital para la Docencia y la Investigación
Dipòsit Digital de la UB
Universidad de Barcelona
© 2021 The Authors.
Idiopathic pulmonary fibrosis is a lethal lung fibrotic disease, associated with aging with a mean survival of 2-5 years and no curative treatment. The GSE4 peptide is able to rescue cells from senescence, DNA and oxidative
Idiopathic pulmonary fibrosis is a lethal lung fibrotic disease, associated with aging with a mean survival of 2-5 years and no curative treatment. The GSE4 peptide is able to rescue cells from senescence, DNA and oxidative