Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Beatriz Castejón‐Vega"'
Autor:
Alvaro González‐Dominguez, Raúl Montañez, Beatriz Castejón‐Vega, Jéssica Nuñez‐Vasco, Débora Lendines‐Cordero, Chun Wang, Gabriel Mbalaviele, José M Navarro‐Pando, Elísabet Alcocer‐Gómez, Mario D Cordero
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 10, Pp 1-7 (2021)
Abstract Inflammation is a hallmark of aging and accelerated aging syndromes such as Hutchinson–Gilford progeria syndrome (HGPS). In this study, we present evidence of increased expression of the components of the NLRP3 inflammasome pathway in HGPS
Externí odkaz:
https://doaj.org/article/741ada3b7d4b430aadbd36423e7df82b
Autor:
María A. Rodríguez-Hernández, P de la Cruz-Ojeda, Mª José López-Grueso, Elena Navarro-Villarán, Raquel Requejo-Aguilar, Beatriz Castejón-Vega, María Negrete, Paloma Gallego, Álvaro Vega-Ochoa, Victor M. Victor, Mario D. Cordero, José A. Del Campo, J. Antonio Bárcena, C. Alicia Padilla, Jordi Muntané
Publikováno v:
Redox Biology, Vol 36, Iss , Pp 101510- (2020)
Cancer cells have unlimited replicative potential, insensitivity to growth-inhibitory signals, evasion of apoptosis, cellular stress, and sustained angiogenesis, invasiveness and metastatic potential. Cancer cells adequately adapt cell metabolism and
Externí odkaz:
https://doaj.org/article/ca51d695b9414e16af105c086821f161
Autor:
Beatriz Castejón-Vega, Alejandro Rubio, Antonio J. Pérez-Pulido, José L. Quiles, Jon D. Lane, Beatriz Fernández-Domínguez, María Begoña Cachón-González, Carmen Martín-Ruiz, Alberto Sanz, Timothy M. Cox, Elísabet Alcocer-Gómez, Mario D. Cordero
Publikováno v:
Cells, Vol 10, Iss 11, p 3122 (2021)
Aims: Tay–Sachs and Sandhoff diseases (GM2 gangliosidosis) are autosomal recessive disorders of lysosomal function that cause progressive neurodegeneration in infants and young children. Impaired hydrolysis catalysed by β-hexosaminidase A (HexA) l
Externí odkaz:
https://doaj.org/article/f52039e69fcc4dfe90d6e42e02924715
Autor:
Beatriz Castejón-Vega, Maurizio Battino, José L. Quiles, Beatriz Bullon, Mario D. Cordero, Pedro Bullón
Publikováno v:
Antioxidants, Vol 10, Iss 1, p 95 (2021)
The Papillon–Lefèvre syndrome (PLS) is a rare autosomal recessive disorder caused by mutations in the Cathepsin C (CTSC) gene, characterized by periodontitis and palmoplantar hyperkeratosis. The main inflammatory deficiencies include oxidative str
Externí odkaz:
https://doaj.org/article/4d1173b3f22f4393a3dc00fc22e75f39
Publikováno v:
Cells, Vol 9, Iss 10, p 2148 (2020)
Aging is associated with metabolic changes and low-grade inflammation in several organs, which may be due to NLRP3 inflammasome activation. Methods: Here, we asked whether age-related liver changes such as lipid metabolism and fibrosis are reduced in
Externí odkaz:
https://doaj.org/article/0631f5eb02d74139aa415c2f23a99a77
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 4829 (2020)
The macromolecular complex known as “inflammasome” is defined as an intracellular multi-protein complex composed of a sensor receptor (PRR), an adaptor protein and an effector enzyme (caspase-1), which oligomerize when they sense danger, such as
Externí odkaz:
https://doaj.org/article/a14f0e5faf2f4310b7780e45ced33a03
Autor:
Beatriz Castejón-Vega, Diego Cañadas-Lozano, Mario D. Cordero, Jesús Ruiz-Cabello, José M. Navarro-Pando, Pedro Bullón, Bernhard Ryffel, Elísabet Alcocer-Gómez, Fabiola Marín-Aguilar
Publikováno v:
GeroScience
Aging is the major risk factor for many metabolic chronic diseases. Several metabolic pathways suffer a progressive impairment during aging including body composition and insulin resistance which are associated to autophagy dysfunction and increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfbca76764574cee4319b47027bc64b5
https://doi.org/10.1007/s11357-019-00151-6
https://doi.org/10.1007/s11357-019-00151-6
Autor:
Mario D. Cordero, José L. Quiles, Maria Begoña Cachón-González, Alberto Sanz, Alejandro Rubio, Pedro Bullón, Carmen Martin-Ruiz, Jon D. Lane, Beatriz Castejón-Vega, Antonio J. Pérez-Pulido, Beatriz Fernández Domínguez, Timothy M. Cox, Débora Lendines-Cordero, Elísabet Alcocer-Gómez
Tay-Sachs and Sandhoff diseases (GM2 gangliosidosis) are autosomal recessive disorders of lysosomal function that cause fatal and progressive neurodegeneration in infants and young children. Impaired hydrolysis catalysed by β-hexosaminidase A (HexA)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::687aabc13355f77b5beabb03f30417b0
https://doi.org/10.1101/2021.05.28.446132
https://doi.org/10.1101/2021.05.28.446132
Autor:
José M. Navarro-Pando, Débora Lendines-Cordero, Mario D. Cordero, Raúl Montañez, Gabriel Mbalaviele, Alvaro González-Dominguez, Jéssica Nuñez-Vasco, Elísabet Alcocer-Gómez, Beatriz Castejón-Vega, Chun Wang
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 10, Pp n/a-n/a (2021)
EMBO Molecular Medicine
EMBO Molecular Medicine
Inflammation is a hallmark of aging and accelerated aging syndromes such as Hutchinson–Gilford progeria syndrome (HGPS). In this study, we present evidence of increased expression of the components of the NLRP3 inflammasome pathway in HGPS skin fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66b979333b420f912cb3d0a1d04d41ad
Autor:
Alejandro Rubio, José L. Quiles, Antonio J. Pérez-Pulido, Beatriz Fernández-Domínguez, Beatriz Castejón-Vega, Elísabet Alcocer-Gómez, Jon D. Lane, Carmen Martin-Ruiz, Maria Begoña Cachón-González, Alberto Sanz, Mario D. Cordero, Timothy M. Cox
Publikováno v:
Cells
Volume 10
Issue 11
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digibug. Repositorio Institucional de la Universidad de Granada
Castejon Vega, B, Rubio, A, Perez-Pulido, A, Quiles, J, Lane, J D, Fernandez-Dominguez, B, Cachon-Gonzales, M, Martin-Ruiz, C, Sanz, A, Cox, T, Alcocer-Gomez, E & Cordero, M 2021, ' L-Arginine Ameliorates Defective Autophagy in GM2 Gangliosidoses by mTOR Modulation ', Cells, vol. 10, no. 11, 3122 . https://doi.org/10.3390/cells10113122
Cells, Vol 10, Iss 3122, p 3122 (2021)
Volume 10
Issue 11
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digibug. Repositorio Institucional de la Universidad de Granada
Castejon Vega, B, Rubio, A, Perez-Pulido, A, Quiles, J, Lane, J D, Fernandez-Dominguez, B, Cachon-Gonzales, M, Martin-Ruiz, C, Sanz, A, Cox, T, Alcocer-Gomez, E & Cordero, M 2021, ' L-Arginine Ameliorates Defective Autophagy in GM2 Gangliosidoses by mTOR Modulation ', Cells, vol. 10, no. 11, 3122 . https://doi.org/10.3390/cells10113122
Cells, Vol 10, Iss 3122, p 3122 (2021)
Aims: Tay–Sachs and Sandhoff diseases (GM2 gangliosidosis) are autosomal recessive disorders of lysosomal function that cause progressive neurodegeneration in infants and young children. Impaired hydrolysis catalysed by β-hexosaminidase A (HexA) l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23aa2a1f3f1a3fa6642540dc57aa082c
http://hdl.handle.net/10481/71460
http://hdl.handle.net/10481/71460