Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Beatriz C.S. Salles"'
Autor:
Daniel Dias, Ricardo Andrez Machado-de-Ávila, Lílian L. Buenoa, Danielle F. de Magalhães-Soares, Mariana P. Lima, Fernanda F. Ramos, Julia A.G. Silveira, Ricardo T. Fujiwaraa, Ana Thereza Chaves, Beatriz C.S. Salles, Daniela P. Lage, Bethina T. Steiner, Patrícia A.F. Ribeiro, Denise Utsch Gonçalves, Lourena E. Costa, Rachel B. Caligiorne, Thaís T.O. Santos, Miguel A. Chávez-Fumagalli, Eduardo A.F. Coelho
Publikováno v:
Immunobiology. 224:163-171
Serological tests are important tools for the diagnosis of Leishmania infection. However, they are not effective markers to diagnose asymptomatic cases of visceral leishmaniasis (VL) and patients developing tegumentary leishmaniasis (TL), since antil
Autor:
Fernanda F. Ramos, Patrícia A.F. Ribeiro, Miguel A. Chávez-Fumagalli, Amanda S. Machado, Beatriz C.S. Salles, Mírian Ívens Fagundes, Daniel Dias, Denise Utsch Gonçalves, Antônio Lúcio Teixeira, Lourena E. Costa, Gerusa B. Carvalho, Ricardo Andrez Machado-de-Ávila, Daniela P. Lage, Eduardo A.F. Coelho, Mariana P. Lima, Mariana C. Duarte, Michelle L. Franklin, Daniel Menezes-Souza
Publikováno v:
Cellular Immunology. 334:61-69
The present study evaluated the cytokine profile in PBMC supernatants and the humoral response in mucosal leishmaniasis (ML) patients and in healthy subjects living in an endemic area. Four proteins, which had previously proven to be antigenic in the
Autor:
Fernanda F. Ramos, Eduardo A.F. Coelho, Regina Lunardi Rocha, Lourena E. Costa, Vívian T. Martins, Fabiana Rocha Da Silva, Amanda S. Machado, Áquila S.B. Portela, Antônio Lúcio Teixeira, Isabela S. Gama, Rachel B. Caligiorne, Thaís T.O. Santos, Mariana P. Lima, Daniela P. Lage, Beatriz C.S. Salles, Daniela R. Lessa, Guilherme F. Nascimento, Manoel Otávio da Costa Rocha, Miguel A. Chávez-Fumagalli
Publikováno v:
Immunobiology. 223:303-309
Visceral leishmaniasis (VL) is a potentially fatal disease, in which the treatment based on chemotherapy is considered toxic. The cure of disease is associated with the life-long Th1-type immunity against the infection. The Th1-related cytokines prod
Autor:
Miguel A. Chávez-Fumagalli, Antônio Lúcio Teixeira, Vívian T. Martins, Fernanda F. Ramos, Mariana C. Duarte, Thaís T.O. Santos, Beatriz C.S. Salles, Daniel Menezes-Souza, Ana C. S. Dias, Lourena E. Costa, Patrícia A.F. Ribeiro, Eduardo A.F. Coelho, Bruno Mendes Roatt, Daniela P. Lage, Érica Leandro Marciano Vieira, Luiz Ricardo Goulart, Daniel Dias, Marcella Rezende Rodrigues, Patrícia Terra Alves
Publikováno v:
Parasites & Vectors, Vol 10, Iss 1, Pp 1-14 (2017)
Parasites & Vectors
Parasites & Vectors
Background The development of a vaccine for the prevention of visceral leishmaniasis (VL) still represents a significant unmet medical need. A human vaccine can be found if one takes into consideration that many people living in endemic areas of dise
Autor:
Patrícia A.F. Ribeiro, Daniela P. Lage, Eduardo A.F. Coelho, Ana Maria Ravena Severino Carvalho, Mariana C. Duarte, Ricardo Andrez Machado-de-Ávila, Daniel Menezes-Souza, Lourena E. Costa, Bruno Mendes Roatt, Danielle F. de Magalhães-Soares, Thaís T.O. Santos, Miguel A. Chávez-Fumagalli, Vívian T. Martins, Daniel Dias, Beatriz C.S. Salles
Publikováno v:
Acta Tropica. 171:8-16
In the present study, the Leishmania braziliensis enolase protein was evaluated as a vaccine candidate against visceral leishmaniasis (VL). The DNA sequence was cloned and the recombinant protein (rEnolase) was evaluated as a vaccine, associated with
Autor:
Ana Maria Ravena Severino Carvalho, Mariana C. Duarte, Lourena E. Costa, Ricardo Andrez Machado-de-Ávila, Daniela P. Lage, Daniel Menezes-Souza, Miguel A. Chávez-Fumagalli, Bruno Mendes Roatt, Thaís T.O. Santos, Patrícia A.F. Ribeiro, Danielle F. de Magalhães-Soares, Beatriz C.S. Salles, Vívian T. Martins, Eduardo A.F. Coelho, Daniel Dias
Publikováno v:
Veterinary Parasitology. 238:77-81
In the present study, Leishmania braziliensis enolase was cloned and the recombinant protein (rEnolase) was evaluated for the serodiagnosis of canine and human visceral leishmaniosis (VL). For the canine VL diagnosis, this study examined serum sample
Autor:
Regina Lunardi Rocha, Emília Rezende Vaz, Lourena E. Costa, Ana C. S. Dias, Denise Utsch Gonçalves, Beatriz C.S. Salles, Luiz Ricardo Goulart, Miguel A. Chávez-Fumagalli, Eduardo A.F. Coelho, Carlos Alberto Pereira Tavares, Mariana C. Duarte, Bruno Mendes Roatt, Daniel Menezes-Souza, Patrícia Terra Alves, Fernanda F. Ramos
Publikováno v:
Diagnostic Microbiology and Infectious Disease. 87:219-225
Serological methods used to diagnose visceral leishmaniasis (VL) are considered minimally invasive, but they present problems related with their sensitivity and/or specificity. In this study, a subtractive selection using the phage display technology
Autor:
Amanda Christine Da Silva Kursancew, Daniel Menezes-Souza, Denise Utsch Gonçalves, Lourena E. Costa, Mariana P. Lima, Roberta Passamani Ambrosio, Mariana C. Duarte, Bruno Mendes Roatt, Thaís T.O. Santos, Beatriz C.S. Salles, Fernanda F. Ramos, Ricardo Andrez Machado-de-Ávila, Eduardo A.F. Coelho, Miguel A. Chávez-Fumagalli
Publikováno v:
Parasitology Research. 116:1197-1206
The serodiagnosis for tegumentary leishmaniasis (TL) presents problems related to the sensitivity and/or specificity of the tests. In the present study, an enzyme-linked immunosorbent assay (ELISA) technique was used to evaluate the performance from
Autor:
Bruno Mendes Roatt, Antônio Lúcio Teixeira, Gerusa B. Carvalho, Thaís T.O. Santos, Lívia M. Carvalho, Patrícia A.F. Ribeiro, Michelle L. Franklin, Daniela P. Lage, Mariana P. Lima, Daniel Menezes-Souza, Renata Mageste Silva, Mariana C. Duarte, Lourena E. Costa, Fernanda F. Ramos, Ana C. S. Dias, Beatriz C.S. Salles, Eduardo A.F. Coelho, Luiz Ricardo Goulart, Daniel Dias, Patrícia Terra Alves, Miguel A. Chávez-Fumagalli
Publikováno v:
Parasitology. 146(3)
In the current study, phage-exposed mimotopes as targets against tegumentary leishmaniasis (TL) were selected by means of bio-panning cycles employing sera of TL patients and healthy subjects, besides the immune stimulation of peripheral blood mononu
Autor:
Bethina T. Steiner, Daniela P. Lage, Denise Utsch Gonçalves, Julia A.G. Silveira, Lourena E. Costa, Ricardo Toshio Fujiwara, Daniel Dias, Miguel A. Chávez-Fumagalli, Eduardo A.F. Coelho, Beatriz C.S. Salles, Fernanda F. Ramos, Lilian Lacerda Bueno, Danielle F. de Magalhães-Soares, Patrícia A.F. Ribeiro, Ricardo Andrez Machado-de-Ávila, Rachel B. Caligiorne, Mariana P. Lima, Thaís T.O. Santos, Ana Thereza Chaves
Publikováno v:
Diagnostic microbiology and infectious disease. 92(3)
In the present study, a conserved Leishmania hypothetical protein, LiHyE, was evaluated for the serodiagnosis of leishmaniasis. Results showed that it presented high sensitivity, specificity, positive predictive value (PPV), and negative predictive v