Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Beatriz Ballester"'
Autor:
Maria Camila Melo-Narváez, Nora Bramey, Fenja See, Katharina Heinzelmann, Beatriz Ballester, Carina Steinchen, Eshita Jain, Kathrin Federl, Qianjiang Hu, Deepesh Dhakad, Jürgen Behr, Oliver Eickelberg, Ali Önder Yildirim, Melanie Königshoff, Mareike Lehmann
Publikováno v:
Cells, Vol 13, Iss 13, p 1129 (2024)
Aging is the main risk factor for chronic lung diseases (CLDs) including idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD). Accordingly, hallmarks of aging like cellular senescence are increased in these patients in
Externí odkaz:
https://doaj.org/article/5fc1e826541d44e8ba31f8cc9cd515a9
Autor:
Beatriz Musoles-Cuenca, Jordi Aguiló-Gisbert, Teresa Lorenzo-Bermejo, Rocío Canales, Beatriz Ballester, Umberto Romani-Cremaschi, Rosa Martínez-Valverde, Elisa Maiques, Diana Marteles, Pablo Rueda, Vicente Rubio, Sergio Villanueva-Saz, Consuelo Rubio-Guerri
Publikováno v:
Animals, Vol 14, Iss 1, p 140 (2023)
In the setting of the recent COVID-19 pandemic, transmission of SARS-CoV-2 to animals has been reported in both domestic and wild animals and is a matter of concern. Given the genetic and functional similarities to humans, non-human primates merit pa
Externí odkaz:
https://doaj.org/article/4600852725a742b2b09b58987f3baca4
Autor:
Javier Milara, Beatriz Ballester, Alfredo de Diego, Marta Calbet, Isabel Ramis, Montserrat Miralpeix, Julio Cortijo
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Non-T2 severe asthma and chronic obstructive pulmonary disease (COPD) are airway chronic inflammatory disorders with a poor response to corticosteroids. LAS194046, a novel pan-Janus kinase (JAK) inhibitor, shows inhibitory effects on T2 alle
Externí odkaz:
https://doaj.org/article/b88406e1f3b144f5ba19e15646f52920
Autor:
Miguel Padilla-Blanco, Francesca Gucciardi, Vicente Rubio, Antonio Lastra, Teresa Lorenzo, Beatriz Ballester, Andrea González-Pastor, Veronica Veses, Giusi Macaluso, Chirag C. Sheth, Marina Pascual-Ortiz, Elisa Maiques, Consuelo Rubio-Guerri, Giuseppa Purpari, Annalisa Guercio
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
To investigate the influence of geographic constrains to mobility on SARS-CoV-2 circulation before the advent of vaccination, we recently characterized the occurrence in Sicily of viral lineages in the second pandemic wave (September to December 2020
Externí odkaz:
https://doaj.org/article/f8ae3abf4fe64cc4b75483d2571542c8
Publikováno v:
European Respiratory Review, Vol 30, Iss 159 (2021)
Recent evidence has demonstrated that mucin 1 (MUC1) is involved in many pathological processes that occur in the lung. MUC1 is a transmembrane protein mainly expressed by epithelial and hematopoietic cells. It has a receptor-like structure, which ca
Externí odkaz:
https://doaj.org/article/fe25eefced674a0a84b0266062380f23
Autor:
Javier Milara, Lucía Díaz-Platas, Sonia Contreras, Pilar Ribera, Inés Roger, Beatriz Ballester, Paula Montero, Ángel Cogolludo, Esteban Morcillo, Julio Cortijo
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-18 (2018)
Abstract Background Lung inflammation in COPD is poorly controlled by inhaled corticosteroids (ICS). Strategies to improve ICS efficacy or the search of biomarkers who may select those patients candidates to receive ICS in COPD are needed. Recent dat
Externí odkaz:
https://doaj.org/article/4409b67e4f164f47b35d3c2f11bb9719
Autor:
Javier Milara, Gracia Hernandez, Beatriz Ballester, Anselm Morell, Inés Roger, P. Montero, Juan Escrivá, José M. Lloris, Maria Molina-Molina, Esteban Morcillo, Julio Cortijo
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is the most rapidly progressive and fatal fibrotic disorder, with no curative therapies. The signal transducer and activator of transcription 3 (STAT3) protein is activated in lung fibroblasts a
Externí odkaz:
https://doaj.org/article/a15d80acb2924a00a0345f0598c07b1b
Autor:
Olivier Burgy, Christoph H. Mayr, Beatriz Ballester Llobell, Arunima Sengupta, Déborah Schenesse, Christina Coughlan, Tanyalak Parimon, Peter Chen, Michael Lindner, Anne Hilgendorff, Matthias Mann, Ali Önder Yildirim, Oliver Eickelberg, Herbert B. Schiller, Mareike Lehmann, Gerald Burgstaller, Melanie Königshoff
Idiopathic pulmonary fibrosis (IPF) is a lethal and chronic lung disease characterized by aberrant intercellular communication, increased extracellular matrix (ECM) deposition, and destruction of functional lung tissue. Extracellular vesicles (EVs) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68a31cfb1b5f105c5100b9610805d9cb
https://doi.org/10.1101/2022.12.22.521499
https://doi.org/10.1101/2022.12.22.521499
Publikováno v:
Oncotarget
Pirfenidone is a pleiotropic molecule approved to treat idiopathic pulmonary fibrosis (IPF). Pirfenidone has demonstrated to downregulate transforming growth factor-β1 (TGF-β1) cellular effects. However, its anti-fibrotic mechanism remains unclear.
Autor:
Esteban J. Morcillo, Alfonso Pastor-Clerigues, Paula Montero, Julio Cortijo, Manuel Alós, Juan Escrivá, Enrique Artigues, Beatriz Ballester, Javier Milara
Publikováno v:
Thorax. 75:132-142
BackgroundSerum KL6/mucin 1 (MUC1) has been identified as a potential biomarker in idiopathic pulmonary fibrosis (IPF), but the role of MUC1 intracellular bioactivation in IPF is unknown.ObjectiveTo characterise MUC1 intracellular bioactivation in IP